| Company Name: |
WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.
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| Tel: |
17702719238 17702719238 |
| Email: |
sales@sun-shinechem.com |
| Products Intro: |
Product Name:ProTAME
CAS:1362911-19-0
Purity:96% HPLC Package:50.0mg;100.0mg; 200.0mg;500mg;1g;5g; 10g
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| Company Name: |
BOC Sciences
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| Tel: |
1-631-485-4226; 16314854226 |
| Email: |
info@bocsci.com |
| Products Intro: |
Product Name:proTAME
CAS:1362911-19-0
Purity:90% Remarks:proTAME is a cell-permeable prodrug of N-4-tosyl-L-arginine methyl ester (TAME), which is an inhibitor of the anaphase-promoting complex/cyclosome (APC/C) suppressing its activation by Cdc20 and Cdh1.
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proTAME manufacturers
- ProTAME
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- $570.00 / 1mg
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2024-10-24
- CAS:1362911-19-0
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | proTAME Basic information |
| Product Name: | proTAME | | Synonyms: | proTAME;pro-Tosyl-L-Arginine Methyl Ester;10,12-Dioxa-6,8-diazatetradec-6-enoic acid, 2-[[(4-methylphenyl)sulfonyl]amino]-9,13-dioxo-14-phenyl-7-[[[[(2-phenylacetyl)oxy]methoxy]carbonyl]amino]-, methyl ester, (2S)-;(2S)-2-[[(4-methylphenyl)sulfonyl]amino]-9,13-dioxo-14-phenyl-7-[[[[(2-phenylacetyl)oxy]methoxy]carbonyl]amino]-10,12-dioxa-6,8-diazatetradec-6-enoicacid,methylester | | CAS: | 1362911-19-0 | | MF: | C34H38N4O12S | | MW: | 726.75 | | EINECS: | | | Product Categories: | | | Mol File: | 1362911-19-0.mol |  |
| | proTAME Chemical Properties |
| density | 1.32±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO: Soluble | | pka | 7.05±0.46(Predicted) | | form | Solid | | color | White to off-white |
| | proTAME Usage And Synthesis |
| Description | ProTAME is an inhibitor of both APC/CFzr and APC/CCdc20. Combinations of proTAME with topoisomerase inhibitors, etoposide and doxorubicin, significantly increase cell death in Multiple Myeloma (MM) cell lines and primary cells, particularly if TOPIIα levels are first increased through pre-treatment with ProTAME. |
| | proTAME Preparation Products And Raw materials |
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