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HUMAN CNTF

HUMAN CNTF Struktur
133423-39-9
CAS-Nr.
133423-39-9
Englisch Name:
HUMAN CNTF
Synonyma:
CNF;CNTF;Anti-HCNTF;HUMAN CNTF;CNTF, HUMAN;RECOMBINANT HUMAN CNTF;CILIARY NEUROTROPHIC FACTOR;HUMAN CILIARY NEUROTROPHIC FACTOR;CILIARY NEUROTROPHIC FACTOR, HUMAN;Anti-CNTF antibody produced in goat
CBNumber:
CB8755968
Summenformel:
Molgewicht:
0
MOL-Datei:
Mol file

HUMAN CNTF Eigenschaften

storage temp. 
−20°C
Aggregatzustand
lyophilized powder

Sicherheit

Kennzeichnung gef?hrlicher Xn
R-S?tze: 22
WGK Germany  3

HUMAN CNTF Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Ciliary Neurotrophic Factor human has been used to study its effect on photoreceptor neuroprotection and Muller glial cell proliferation in zebrafish retina. It has also been used to study the effects of intravitreal injection of ciliary neurotrophic factor (CNTF) on photoreceptor injury and BRB (blood-retinal barrier) breakdown in transgenic model.

Allgemeine Beschreibung

The CNTF (ciliary neurotrophic factor) gene encodes a cytokine, and is mapped to human chromosome 11q12.1.

Biochem/physiol Actions

Ciliary neurotrophic factor (CNTF) was first identified as a survival factor for neurons from the ciliary ganglion of chicken embryos. Most of its known actions are restricted to cells of the nervous system, including motor neurons, sympathetic ganglion neurons, sensory neurons, hippocampal neurons, and medial septal neurons. CNTF also prevents degeneration of motor axons after axotomy and promotes astrocyte differentiation and oligodendrocyte survival and maturation. Outside the nervous system, CNTF maintains embryonic stem cells in an undifferentiated, pluripotent state. CNTF is structurally related to leukemia inhibitory factor (LIF), interleukin-6 (IL-6), interleukin-11 (IL-11) and oncostatin M (OSM). CNTF exerts its actions through the activation of the high-affinity CTNF receptor complex, which contains the ligand-binding α-subunit (CNTF Rα) and two signal transducing β-subunits (LIF Rβ and gp130). The LIF Rβ subunit is also shared by receptors for LIF and OSM. The gp130 subunit is also shared by receptors for LIF, OSM, IL-6, and IL-11. CNTF is localized in the cell nucleus subsequent to receptor binding. Human and rat CNTF share ~83% sequence homology and show cross-reactivity in bioactivity.

HUMAN CNTF Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


HUMAN CNTF Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 65)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51456 80
Shanghai Kanglang Biotechnology Co., Ltd. 021-61998208 18217752821
sales@klbio.cn China 9618 58
Absin Bioscience Inc. 021-38015121 15000105423
wulan@absin.cn China 24731 58
Wuhan Chemstan Biotechnology Co., Ltd. 027-65317797 15926423062
422450190@qq.com China 10424 58
Shanghai Yaji Biological Technology Co., Ltd. 021-34661275 15301693058
yajikit@163.com China 9670 58
Shanghai Yingxin Laboratory Equipment Co., Ltd. 021-021-59178156 17002132182
3146474380@qq.com China 11603 58
Shanghai Huzhen Industrial Co., LTD 021-60345367 13916550749
sales@shzbio.com China 9966 58
Biolab Reagents 027-65279366 18108604862
products@biolabreagent.com China 9818 58
ACROBiosystems 18514007688
jiaxin.zhao@acrobiosystems.com China 1183 58
4008-099-669
23419001name@qq.com CHINA 73043 58

  • RECOMBINANT HUMAN CNTF
  • HUMAN CILIARY NEUROTROPHIC FACTOR
  • HUMAN CNTF
  • CILIARY NEUROTROPHIC FACTOR
  • CILIARY NEUROTROPHIC FACTOR, HUMAN
  • CNF
  • CNTF
  • CNTF, HUMAN
  • Ciliary Neurotrophic Factor from rat
  • Anti-CNTF antibody produced in goat
  • Anti-HCNTF
  • Recombinant Human CNTF Protein, No Tag
  • 133423-39-9
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