| Company Name: |
Shanghai Yifei Biotechnology Co. , Ltd.
|
| Tel: |
021-65675885 18964387627 |
| Email: |
customer_service@efebio.com |
| Products Intro: |
Product Name:UNC10112785
CAS:748142-06-5
Purity:98% Package:5mg;10mg;25mg
|
| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:UNC10112785
CAS:748142-06-5
Package:25mg/RMB 10600;50mg/RMB 13800;100mg/RMB 17500
|
2-Pyrimidinamine, N-[4-(1-methylethyl)phenyl]-4-pyrazolo[1,5-b]pyridazin-3-yl- manufacturers
- UNC10112785
-
- $1520.00 / 25mg
-
2024-10-28
- CAS:748142-06-5
- Min. Order:
- Purity:
- Supply Ability: 10g
|
| | 2-Pyrimidinamine, N-[4-(1-methylethyl)phenyl]-4-pyrazolo[1,5-b]pyridazin-3-yl- Basic information |
| | 2-Pyrimidinamine, N-[4-(1-methylethyl)phenyl]-4-pyrazolo[1,5-b]pyridazin-3-yl- Chemical Properties |
| density | 1.28±0.1 g/cm3(Predicted) | | pka | 2.13±0.10(Predicted) |
| | 2-Pyrimidinamine, N-[4-(1-methylethyl)phenyl]-4-pyrazolo[1,5-b]pyridazin-3-yl- Usage And Synthesis |
| Description | UNC10112785 is a novel potent inhibitor of CDK8, CDK19, and CDK9 with IC50 at 1.05, 2.67, and 19.9 nM, respectively, causing MYC loss through both transcriptional and posttranslational mechanisms, and suppressing PDAC anchorage-dependent and anchorage-independent growth, inducing the substantial loss of MYC protein in both two-dimensional (2D) and 3D cell cultures. |
| | 2-Pyrimidinamine, N-[4-(1-methylethyl)phenyl]-4-pyrazolo[1,5-b]pyridazin-3-yl- Preparation Products And Raw materials |
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