Boc-Val-Ala-PAB manufacturers
- Boc-Val-Ala-PAB
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- $0.00 / 1g
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2024-03-29
- CAS:1884577-99-4
- Min. Order: 1g
- Purity: >95.00%
- Supply Ability: 1g
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| | Boc-Val-Ala-PAB Basic information |
| Product Name: | Boc-Val-Ala-PAB | | Synonyms: | Boc-Val-Ala-PAB;(S)-2-(Boc-amino)-N-[(S)-1-[[4-(hydroxymethyl)phenyl]amino]-1-oxo-2-propyl]-3-methylbutanamide;tert-Butyl ((S)-1-(((S)-1-((4-(hydroxymethyl)phenyl)amino)-1-oxopropan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)carbamate;L-Alaninamide, N-[(1,1-dimethylethoxy)carbonyl]-L-valyl-N-[4-(hydroxymethyl)phenyl]-;tert-butyl N-[(1S)-1-{[(1S)-1-[(4-(hydroxymethyl)phenyl)carbamoyl]ethyl]carbamoyl}-2-methylpropyl]carbamate;tert-butyl N-[(2S)-1-[[(2S)-1-[4-(hydroxymethyl)anilino]-1-oxopropan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]carbamate | | CAS: | 1884577-99-4 | | MF: | C20H31N3O5 | | MW: | 393.48 | | EINECS: | | | Product Categories: | Linker | | Mol File: | 1884577-99-4.mol |  |
| | Boc-Val-Ala-PAB Chemical Properties |
| Boiling point | 653.7±55.0 °C(Predicted) | | density | 1.166±0.06 g/cm3(Predicted) | | form | Solid | | pka | 11.26±0.46(Predicted) | | color | White to off-white |
| | Boc-Val-Ala-PAB Usage And Synthesis |
| Description | Boc-Val-Ala-PAB is a cleavable ADC linker. The Val-Ala is effectively cleaved by lysosomal proteolytic enzymes while being highly stable in human plasma, making this a potentent stragy in ADC linker design. The t-butyl protected carboxyl group can be deprotected under acidic conditions. |
| | Boc-Val-Ala-PAB Preparation Products And Raw materials |
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