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| | Tylocrebrine Basic information |
| Product Name: | Tylocrebrine | | Synonyms: | Tylocrebrine;[13aR,(+)]-9,11,12,13,13a,14-Hexahydro-2,3,5,6-tetramethoxydibenzo[f,h]pyrrolo[1,2-b]isoquinoline;Brn 1555044;Dibenzo(F,H)pyrrolo(1,2-B)isoquinoline, 9,11,12,13,13A,14-hexahydro-2,3,5,6-tetramethoxy-;Dibenzo(F,H)pyrrolo(1,2-B)isoquinoline, 9,11,12,13,13A,14-hexahydro-2,3,5,6-tetramethoxy-, (R)- (9ci);Lylocrebrine;Nsc-60387;Tylocerebrine | | CAS: | 6879-02-3 | | MF: | C24H27NO4 | | MW: | 393.48 | | EINECS: | | | Product Categories: | | | Mol File: | 6879-02-3.mol |  |
| | Tylocrebrine Chemical Properties |
| Melting point | 220 °C | | Boiling point | 559.9±45.0 °C(Predicted) | | density | 1.26±0.1 g/cm3(Predicted) | | pka | 7.62±0.20(Predicted) |
| | Tylocrebrine Usage And Synthesis |
| Uses | Tylocrebrine is a compound with anticancer activity. Its clinical research was interrupted due to toxicity issues. By making it into targeted nanoparticles, its inhibitory index can be improved, the killing effect on tumor cells can be enhanced and brain penetration can be reduced. | | References | [1] Reformulating Tylocrebrine in Epidermal Growth Factor Receptor Targeted Polymeric Nanoparticles Improves Its Therapeutic Index DOI:10.1021/acs.molpharmaceut.5b00173 |
| | Tylocrebrine Preparation Products And Raw materials |
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