Company Name: |
Shanghai YuanYe Biotechnology Co., Ltd.
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Tel: |
021-61312847; 18021002903 |
Email: |
3008007409@qq.com |
Products Intro: |
Product Name:WAY-358024 CAS:70169-39-0 Purity:98% Package:5mg Remarks:S34099
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| Benzoic acid, 2-hydroxy-, 2-(1,2-dihydro-2-oxo-3H-indol-3-ylidene)hydrazide Basic information |
| Benzoic acid, 2-hydroxy-, 2-(1,2-dihydro-2-oxo-3H-indol-3-ylidene)hydrazide Chemical Properties |
Melting point | >250 °C | density | 1.44±0.1 g/cm3(Predicted) | pka | 8.26±0.30(Predicted) |
| Benzoic acid, 2-hydroxy-, 2-(1,2-dihydro-2-oxo-3H-indol-3-ylidene)hydrazide Usage And Synthesis |
Uses | GSK-3β inhibitor 26 (Compound D14) is a GSK-3β inhibitor with an IC50 of 18.23 μM. GSK-3β inhibitor 26 can be used in the research of cancer, inflammation and neurodegenerative diseases[1]. | IC 50 | GSK-3β: 18.23 μM (IC50) | References | [1] Dou X, et al. Discovery of new GSK-3β inhibitors through structure-based virtual screening. Bioorg Med Chem Lett. 2018 Jan 15;28(2):160-166. DOI:10.1016/j.bmcl.2017.11.036 |
| Benzoic acid, 2-hydroxy-, 2-(1,2-dihydro-2-oxo-3H-indol-3-ylidene)hydrazide Preparation Products And Raw materials |
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