- Arundic Acid
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- $37.00 / 5mg
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2024-11-16
- CAS:185517-21-9
- Min. Order:
- Purity: 98%
- Supply Ability: 10g
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| | (R)-2-PROPYLOCTANOIC ACID Basic information |
| | (R)-2-PROPYLOCTANOIC ACID Chemical Properties |
| Boiling point | 289℃ | | density | 0.908 | | Fp | 154℃ | | storage temp. | Refrigerator | | solubility | Chloroform (Slightly), Ethanol (Slightly), Ethyl Acetate (Slightly) | | form | Oil | | pka | 4.82±0.40(Predicted) | | color | Clear Colorless to Clear Pale Yellow |
| | (R)-2-PROPYLOCTANOIC ACID Usage And Synthesis |
| Description | Arundic acid is an inhibitor of astrocyte activation. It reduces increases in brain glial fibrillary acid protein (GFAP) and S100β levels, markers of astrocyte activation, in a rat model of permanent focal ischemia induced by middle cerebral artery occlusion when administered at a dose of 10 mg/kg. Arundic acid (3 and 10 mg/kg) decreases the number of TUNEL-positive neurons, reduces infarct size, and improves motor performance in the rotarod test in the same model. It also reduces descent time and time to turn in a pole test, indicating reversal of motor deficits, in a mouse model of MPTP-induced Parkinson''s disease when administered at a dose of 30 mg/kg. | | Chemical Properties | Clear Colorless Oil | | Uses | An astrocyte modulating agent, in acute ischemic stroke. | | storage | Store at +4°C |
| | (R)-2-PROPYLOCTANOIC ACID Preparation Products And Raw materials |
| Raw materials | Octanoic acid, 2-(2-propyn-1-yl)-, (2S)--->Octanamide, 2-propyl-, (2R)--->1-Octanone, 1-[(3aS,6R,7aR)-tetrahydro-8,8-dimethyl-2,2-dioxido-3H-3a,6-methano-2,1-benzisothiazol-1(4H)-yl]- | | Preparation Products | D-CAMPHOR-->S-(+)-Arundic Acid |
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