Bozepinib manufacturers
- Bozepinib
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- $1980.00 / 50mg
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2024-10-28
- CAS:1207993-83-6
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | Bozepinib Basic information |
| Product Name: | Bozepinib | | Synonyms: | Bozepinib;4,1-Benzoxazepine, 3-(2,6-dichloro-9H-purin-9-yl)-1,2,3,5-tetrahydro-1-[(4-nitrophenyl)sulfonyl]- | | CAS: | 1207993-83-6 | | MF: | C20H14Cl2N6O5S | | MW: | 521.33 | | EINECS: | | | Product Categories: | | | Mol File: | 1207993-83-6.mol |  |
| | Bozepinib Chemical Properties |
| Melting point | 173-175 °C | | Boiling point | 696.9±65.0 °C(Predicted) | | density | 1.74±0.1 g/cm3(Predicted) | | pka | -1.55±0.10(Predicted) |
| | Bozepinib Usage And Synthesis |
| Enzyme inhibitor | This potent antitumor agent (FW = 521.33 g/mol), sysyematically known as (RS)-2,6-dichloro-9-[1-(p-nitrobenzenesulfonyl)-1,2,3,5-tetrahydro-4,1- benzoxazepin-3-yl]-9H-purine, induces apoptosis in breast and colon cancer cells via inhibition (IC50 = 0.3–2 μM) of the the double-stranded RNAdependent protein kinase, PKR, but not p53. Moreover, interferon enhances cytotoxicity of bozepinib in colon and breast cancer cells by increasing apoptotic cell death. |
| | Bozepinib Preparation Products And Raw materials |
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