| Company Name: |
Chengdu Pukang Biotechnology Co., Ltd
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| Tel: |
028-82550498 19102685862 |
| Email: |
sales@pu-kang.com |
| Products Intro: |
Product Name:Hydroxy-PEG3-MS
CAS:139115-89-2
Purity:95% Package:1g,5g,10g
|
| Company Name: |
Borenpharm Co., Ltd
|
| Tel: |
027-65563561 |
| Email: |
sales@borenpharm.com |
| Products Intro: |
Product Name:Hydroxy-PEG3-MS
CAS:139115-89-2
Purity:95% HPLC Package:1g; 5g Remarks:7.6g
|
| Company Name: |
Zhengzhou Acme Chemical Co., Ltd.
|
| Tel: |
0371-0371-55629727 13323845623 |
| Email: |
2885676761@qq.com |
| Products Intro: |
CAS:139115-89-2
Purity:0.98 Package:100g;250g;500g;1kg
|
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| | Hydroxy-PEG3-Mes Basic information |
| Product Name: | Hydroxy-PEG3-Mes | | Synonyms: | Hydroxy-PEG3-Mes;Hydroxy-PEG3-MS;Ms-peg4;CAS_139115-89-2;3,6,9-Trioxa-2-thiaundecan-11-ol, 2,2-dioxide;2-(2-(2-Hydroxyethoxy)ethoxy)ethyl methanesulfonate | | CAS: | 139115-89-2 | | MF: | C7H16O6S | | MW: | 228.26 | | EINECS: | | | Product Categories: | | | Mol File: | 139115-89-2.mol |  |
| | Hydroxy-PEG3-Mes Chemical Properties |
| Boiling point | 398.2±27.0 °C(Predicted) | | density | 1.256±0.06 g/cm3(Predicted) | | pka | 14.36±0.10(Predicted) | | form | Liquid | | color | Colorless to light yellow |
| | Hydroxy-PEG3-Mes Usage And Synthesis |
| Biological Activity | Hydroxy-PEG3-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. | | References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| | Hydroxy-PEG3-Mes Preparation Products And Raw materials |
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