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| | 2,6-Dimethoxybenzoic acid Basic information |
| Product Name: | 2,6-Dimethoxybenzoic acid | | Synonyms: | 2,6-DIMETHOXYBENZOIC ACID;RARECHEM AL BO 1076;2,6-dimethoxy-benzoicaci;Benzoicacid,2,6-dimethoxy-;2,6-Dimethoxybenzoic;γ-Resorcylic acid diMethyl ether;2,6-DiMethoxybenzoic acid, 99% 25GR;2,6-Dimethoxybenzoic acid,99% | | CAS: | 1466-76-8 | | MF: | C9H10O4 | | MW: | 182.17 | | EINECS: | 215-985-4 | | Product Categories: | Agrochemical intermediate;Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts;C9;Carbonyl Compounds;Carboxylic Acids | | Mol File: | 1466-76-8.mol |  |
| | 2,6-Dimethoxybenzoic acid Chemical Properties |
| | 2,6-Dimethoxybenzoic acid Usage And Synthesis |
| Chemical Properties | white to off-white crystalline powder. Hardly soluble in water, soluble in alkali and organic solvents, such as benzene and toluene. | | Uses | 2,6-Dimethoxybenzoic Acid is used in the synthesis of indoles as well as coumarins related to Novobiocin (N888500), used as potent inhibitors of heat-shock protein 90 in the treatment of breast cancer. | | Preparation | 2,6-Dimethoxybenzoic acid is the key intermediate in the preparation of gamma-resorcylic acid which has been described as having activity against rheumatic fever.
The Preparation of 2,6-Dimethoxybenzoic Acid
Cite this: J. Org. Chem. 1956, 21, 3, 368–369
Publication Date:March 1, 1956
https://doi.org/10.1021/jo01109a604 | | Definition | ChEBI: 2,6-Dimethoxybenzoic acid is a member of benzenes and a carbonyl compound. It is a polyphenol compound found in foods of plant origin. | | Synthesis Reference(s) | Synthetic Communications, 22, p. 13, 1992 DOI: 10.1080/00397919208021074 | | Flammability and Explosibility | Not classified | | Purification Methods | Crystallise the acid from water or 1,1-dichloroethane (m 187.5-188.5o). [Beilstein 10 H 388, 10 I 185, 10 II 259, 10 III 1401, 10 IV 1456.] |
| | 2,6-Dimethoxybenzoic acid Preparation Products And Raw materials |
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