NSC 663284
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3物価
選択條件：
ブランド
- 富士フイルム和光純薬株式會(huì)社(wako)
- Sigma-Aldrich Japan
パッケージ
- 5mg
- 10mg
- 25mg
- 生産者富士フイルム和光純薬株式會(huì)社(wako)
- 製品番號(hào)W01TOC1867
- 製品説明
- 英語製品説明NSC 663284
- 包裝単位10mg
- 価格￥90000
- 更新しました2024-03-01
- 購入
- 生産者Sigma-Aldrich Japan
- 製品番號(hào)N7537
- 製品説明 ≥98% (HPLC), solid
- 英語製品説明NSC 663284 ≥98% (HPLC), solid
- 包裝単位25mg
- 価格￥143000
- 更新しました2024-03-01
- 購入
- 生産者Sigma-Aldrich Japan
- 製品番號(hào)N7537
- 製品説明 ≥98% (HPLC), solid
- 英語製品説明NSC 663284 ≥98% (HPLC), solid
- 包裝単位5mg
- 価格￥47300
- 更新しました2024-03-01
- 購入
| 生産者 | 製品番號(hào) | 製品説明 | 包裝単位 | 価格 | 更新時(shí)間 | 購入 |
|---|---|---|---|---|---|---|
| 富士フイルム和光純薬株式會(huì)社(wako) | W01TOC1867 | NSC 663284 |
10mg | ￥90000 | 2024-03-01 | 購入 |
| Sigma-Aldrich Japan | N7537 | ≥98% (HPLC), solid NSC 663284 ≥98% (HPLC), solid |
25mg | ￥143000 | 2024-03-01 | 購入 |
| Sigma-Aldrich Japan | N7537 | ≥98% (HPLC), solid NSC 663284 ≥98% (HPLC), solid |
5mg | ￥47300 | 2024-03-01 | 購入 |
プロパティ
沸點(diǎn) :478.8±45.0 °C(Predicted)
比重(密度) :1.41±0.1 g/cm3(Predicted)
貯蔵溫度 :2-8°C
溶解性 :DMSO: 16 mg/mL
外見 :solid
酸解離定數(shù)(Pka) :6.79±0.10(Predicted)
色 :red
Sensitive :Light Sensitive
安定性： :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
比重(密度) :1.41±0.1 g/cm3(Predicted)
貯蔵溫度 :2-8°C
溶解性 :DMSO: 16 mg/mL
外見 :solid
酸解離定數(shù)(Pka) :6.79±0.10(Predicted)
色 :red
Sensitive :Light Sensitive
安定性： :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
安全情報(bào)
| 絵表示(GHS): |
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| 注意喚起語: | Warning | ||||||||||||||||||||||||||||
| 危険有害性情報(bào): |
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説明
Three genes encode dual specificity phosphatases that are Cdc25 homologs. The phosphatases, Cdc25A through C, are proto-oncogenes and are often over-expressed in cancers. NSC 663284 is a potent, cell-permeable, and irreversible inhibitor of all Cdc25 isoforms, with preference for Cdc25A (IC50 = 29, 95, and 89 nM for Cdc25A, Cdc25B2, and Cdc25C, respectively). NSC 663284 poorly inhibits other phosphatases, including Vaccinia virus VH1-related (IC50 = 4.0 μM), PTP1B (no inhibition), and the mitogen-activated protein kinase phosphatases (MKP) MKP-1 or -3 (no inhibition). By inhibiting Cdc25 isoforms, NSC 663284 prevents the dephosphorylation and activation of Cdk1 and Cdk2, arrests cells at both G1 and G2/M phases, and prevents the proliferation of several human tumor cell lines.関連商品価格
- (S)-(+)-カンプトテシン
￥2900-427500 - CL 82198 HYDROCHLORIDE
￥14100-65700 - ZM336372
￥7800-573100
供給者とメーカー
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Sigma-Aldrich
Shanghai EFE Biological Technology Co., Ltd.