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D-ガラクトサミン

D-ガラクトサミン price.
  • ¥66900 - ¥259900
  • 化學(xué)名: D-ガラクトサミン
  • 英語名: D-GALACTOSAMINE
  • 別名:(+)-D-ガラクトサミン;ガラクトサミン;2-アミノ-2-デオキシ-D-ガラクトース;コンドロサミン;D-ガラクトサミン;(2R,3R,4R,5R)-2-アミノ-3,4,5,6-テトラヒドロキシヘキサナール
  • CAS番號: 7535-00-4
  • 分子式: C6H13NO5
  • 分子量: 179.17
  • EINECS:
  • MDL Number:MFCD01941613
2物価
選択條件:
ブランド
  • 富士フイルム和光純薬株式會社(wako)
パッケージ
  • 250mg
  • 1g
  • 生産者富士フイルム和光純薬株式會社(wako)
  • 製品番號W01MAS099675
  • 製品説明
  • 英語製品説明(2R,3R,4R,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal
  • 包裝単位1g
  • 価格¥259900
  • 更新しました2024-03-01
  • 購入
  • 生産者富士フイルム和光純薬株式會社(wako)
  • 製品番號W01MAS099675
  • 製品説明
  • 英語製品説明(2R,3R,4R,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal
  • 包裝単位250mg
  • 価格¥66900
  • 更新しました2020-09-21
  • 購入
生産者 製品番號 製品説明 包裝単位 価格 更新時(shí)間 購入
富士フイルム和光純薬株式會社(wako) W01MAS099675
(2R,3R,4R,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal
1g ¥259900 2024-03-01 購入
富士フイルム和光純薬株式會社(wako) W01MAS099675
(2R,3R,4R,5R)-2-Amino-3,4,5,6-tetrahydroxyhexanal
250mg ¥66900 2020-09-21 購入

プロパティ

融點(diǎn)  :185 °C
沸點(diǎn)  :532.5±50.0 °C(Predicted)
比重(密度)  :1.491±0.06 g/cm3(Predicted)
貯蔵溫度  :under inert gas (nitrogen or Argon) at 2–8 °C
溶解性 :Soluble (water), slightly soluble (ethanol)
酸解離定數(shù)(Pka) :11.21±0.45(Predicted)
光學(xué)活性 (optical activity) :Alpha form +124 → +93 Beta form +47 → +93

安全情報(bào)

絵表示(GHS): GHS hazard pictograms
注意喚起語: Warning
危険有害性情報(bào):
コード 危険有害性情報(bào) 危険有害性クラス 區(qū)分 注意喚起語 シンボル P コード
H317 アレルギー性皮膚反応を起こすおそれ 感作性、皮膚 1 警告 GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H319 強(qiáng)い眼刺激 眼に対する重篤な損傷性/眼刺激 性 2A 警告 GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
注意書き:
P280 保護(hù)手袋/保護(hù)衣/保護(hù)眼鏡/保護(hù)面を著用するこ と。
P305+P351+P338 眼に入った場合:水で數(shù)分間注意深く洗うこと。次にコ ンタクトレンズを著用していて容易に外せる場合は外す こと。その後も洗浄を続けること。

説明

Galactosamine is a model hepatotoxicant, induces hepatitis characterized by neutrophilic infiltration, and kills the animal by fulminant hepatic failure. Galactosamine, an amino derivative of sugar galactose, has been used as a model hepatotoxicant since the first reports of hepatotoxicity in late 1970s by Keppler and associates. Galactosamine-induced hepatitis has been a model of choice to study various aspects of liver disease, including mechanisms of toxicant-induced apoptosis and necrosis, liver tissue repair, neutrophil infiltration and transmigration, and the role of endotoxin or lipopolysaccharide (LPS) in initiating liver injury.
Humans and animals synthesize galactosamine in the body. Galactosamine (a type of hexosamine) is formed when an amino group replaces one of the hydroxy groups of a sixcarbon sugar, or hexose. The human body utilizes uridine diphosphate (UDP)-N-acetyl-D-glucosamine or glucosamine as a precursor to synthesize this compound, and is most often found in the form N-acetyl-D-galactosamine (often referred to as N-acetylgalactosamine). Most importantly, galactosamine is a constituent of hyaluronic acid, a powerful water-binding agent. Many different types of tissues in human body contain hyaluronic acid, which acts as a lubricating agent in the synovial fluid of joints and in connective tissues. Hyaluronic acid also acts as a lubricating agent in the vitreous humor of the eyeball. Hyaluronic acid has considerable medicinal value; it is often used in wound healing, burn dressings, osteoarthritis treatment, cataract or corneal transplantation surgery, and various types of plastic surgeries.