Vadimezan
|
- $25 - $20100
- Product name: Vadimezan
- CAS: 117570-53-3
- MF: C17H14O4
- MW: 282.29
- EINECS:700-141-4
- MDL Number:MFCD00870555
- Synonyms:5,6-dimethylxanthenoneacetic acid;DMXAA;vadimezan;(5,6-DIMETHYL-9-OXO-XANTHEN)-4-ACETIC ACID;5,6-Dimethyl-9-oxo-9H-xanthene-4-acetic acid;5,6-Dimethylxanthenone-4-acetic acid;NSC-640488;NSC-649488
50 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chem-Impex
- ChemScene
- Crysdot
- CSNpharm
- DC Chemicals
- Matrix Scientific
- Oakwood
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
Package
- 1unit
- 1mg
- 5mg
- 10mg
- 10
- 25MG
- 50mg
- 100mg
- 250mg
- 1g
- 50
- 5g
- 10mM(in 1mL DMSO)
- ManufacturerAK Scientific
- Product numberSYN5518
- Product descriptionVadimezan
- Packaging100mg
- Price$1296
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA140665
- Product description2-(5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)aceticacid 98+%
- Packaging5mg
- Price$25
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA140665
- Product description2-(5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)aceticacid 98+%
- Packaging10mg
- Price$32
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA140665
- Product description2-(5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)aceticacid 98+%
- Packaging50mg
- Price$54
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA140665
- Product description2-(5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)aceticacid 98+%
- Packaging100mg
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA140665
- Product description2-(5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)aceticacid 98+%
- Packaging250mg
- Price$116
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA140665
- Product description2-(5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)aceticacid 98+%
- Packaging1g
- Price$299
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA140665
- Product description2-(5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)aceticacid 98+%
- Packaging5g
- Price$1101
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0005183
- Product descriptionDMXAA 95.00%
- Packaging25MG
- Price$892.5
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0005183
- Product descriptionDMXAA 95.00%
- Packaging1G
- Price$20100
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8233
- Product descriptionDMXAA(Vadimezan)
- Packaging1unit
- Price$28
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8233
- Product descriptionDMXAA(Vadimezan)
- Packaging5mg
- Price$85
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8233
- Product descriptionDMXAA(Vadimezan)
- Packaging10mM(in 1mL DMSO)
- Price$100
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8233
- Product descriptionDMXAA(Vadimezan)
- Packaging25mg
- Price$260
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8233
- Product descriptionDMXAA(Vadimezan)
- Packaging100mg
- Price$680
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS449215
- Product description2-(5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)aceticacid ≥98%
- Packaging5mg
- Price$25
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | SYN5518 | Vadimezan | 100mg | $1296 | 2021-12-16 | Buy |
| Ambeed | A140665 | 2-(5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)aceticacid 98+% | 5mg | $25 | 2021-12-16 | Buy |
| Ambeed | A140665 | 2-(5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)aceticacid 98+% | 10mg | $32 | 2021-12-16 | Buy |
| Ambeed | A140665 | 2-(5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)aceticacid 98+% | 50mg | $54 | 2021-12-16 | Buy |
| Ambeed | A140665 | 2-(5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)aceticacid 98+% | 100mg | $80 | 2021-12-16 | Buy |
| Ambeed | A140665 | 2-(5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)aceticacid 98+% | 250mg | $116 | 2021-12-16 | Buy |
| Ambeed | A140665 | 2-(5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)aceticacid 98+% | 1g | $299 | 2021-12-16 | Buy |
| Ambeed | A140665 | 2-(5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)aceticacid 98+% | 5g | $1101 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0005183 | DMXAA 95.00% | 25MG | $892.5 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | API0005183 | DMXAA 95.00% | 1G | $20100 | 2021-12-16 | Buy |
| ApexBio Technology | A8233 | DMXAA(Vadimezan) | 1unit | $28 | 2021-12-16 | Buy |
| ApexBio Technology | A8233 | DMXAA(Vadimezan) | 5mg | $85 | 2021-12-16 | Buy |
| ApexBio Technology | A8233 | DMXAA(Vadimezan) | 10mM(in 1mL DMSO) | $100 | 2021-12-16 | Buy |
| ApexBio Technology | A8233 | DMXAA(Vadimezan) | 25mg | $260 | 2021-12-16 | Buy |
| ApexBio Technology | A8233 | DMXAA(Vadimezan) | 100mg | $680 | 2021-12-16 | Buy |
| Arctom | AS449215 | 2-(5,6-Dimethyl-9-oxo-9H-xanthen-4-yl)aceticacid ≥98% | 5mg | $25 | 2021-12-16 | Buy |
Properties
Melting point :259-261 °C
Boiling point :520.9±50.0 °C(Predicted)
Density :1.321±0.06 g/cm3(Predicted)
vapor pressure :0Pa at 20℃
storage temp. :2-8°C
solubility :DMSO: 17 mg/mL, soluble
form :solid
pka :4.21±0.10(Predicted)
color :light brown
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 3 months.
Boiling point :520.9±50.0 °C(Predicted)
Density :1.321±0.06 g/cm3(Predicted)
vapor pressure :0Pa at 20℃
storage temp. :2-8°C
solubility :DMSO: 17 mg/mL, soluble
form :solid
pka :4.21±0.10(Predicted)
color :light brown
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 3 months.
Safety Information
| Symbol(GHS): |
 
|
|||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal word: | Warning | |||||||||||||||||||||
| Hazard statements: |
|
|||||||||||||||||||||
| Precautionary statements: |
|
Description
DMXAA is a xanthene which acts as a tumor vascular disrupting agent, inducing apoptosis in tumor vascular endothelium resulting in necrosis at the tumor core. It potently activates the TANK-binding kinase 1-interferon regulatory factor 3 (TBK1/IRF3) signaling pathway in leukocytes, inducing type-I-interferon (IFN) production. Specifically, DMXAA activates the mitochondria- and endoplasmic reticulum-associated protein known as stimulator of interferon genes (STING), leading to TBK1/IRF3 signaling. DMXAA signals through mouse STING but not human STING. In addition, DMXAA significantly inhibits several kinases in endothelial cells, including the vascular endothelial growth factor (VEGF) receptors VEGFR1 and VEGFR2 (IC50 = 119 and 11 μM, respectively).Related product price
- N,N-Dimethylformamide
$11.2-12200 - Poly(dimethylsiloxane)
$21.65-2858.63 - Dimethyl sulfoxide
$15-120900
