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ChemicalBook >> CAS DataBase List >> Tropicamide

Tropicamide

Tropicamide price.
  • $5 - $1960
  • Product name: Tropicamide
  • CAS: 1508-75-4
  • MF: C17H20N2O2
  • MW: 284.35
  • EINECS:216-140-2
  • MDL Number:MFCD00058580
  • Synonyms:Tropicamide (200 mg);(2R)-N-ethyl-3-hydroxy-2-phenyl-N-(pyridin-4-ylMethyl)propanaMide;TropicaMide N-Ethyl-3-hydroxy-2-phenyl-N-(pyridin-4-ylMethyl)propanaMide;Tropicamide for peak identification;n-ethyl-2-phenyl-n-(4-pyridylmethyl)-hydracrylamid ;N-Ethyl-3-hydroxy-2-phenyl-N-(4-pyridinylmethyl)propanamide;n-ethyl-alpha-(hydroxymethyl)-n-(4-pyridinylmethyl)-benzeneacetamid ;ro1-7683
35 prices
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  • AK Scientific
  • Alfa Aesar
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • Crysdot
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
  • Tocris
  • TRC
  • Usbiological
Package
  • 0.5g
  • 500mg
  • 10G
  • y0001316
  • 100
  • 200mg
  • t2580000
  • 1unit
  • 100mg
  • 250mg
  • 1g
  • 25g
  • 5g
  • 10mM(in 1mL DMSO)
  • ManufacturerAK Scientific
  • Product numberJ95246
  • Product descriptionTropicamide
  • Packaging25g
  • Price$480
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ61132
  • Product descriptionTropicamide, 99+%
  • Packaging1g
  • Price$52.4
  • Updated2023-06-20
  • Buy
  • ManufacturerAmbeed
  • Product numberA130661
  • Product descriptionTropicamide 98%
  • Packaging100mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA130661
  • Product descriptionTropicamide 98%
  • Packaging250mg
  • Price$7
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA130661
  • Product descriptionTropicamide 98%
  • Packaging1g
  • Price$11
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA130661
  • Product descriptionTropicamide 98%
  • Packaging5g
  • Price$38
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA130661
  • Product descriptionTropicamide 98%
  • Packaging25g
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0004531
  • Product descriptionTROPICAMIDE 95.00%
  • Packaging1G
  • Price$137.55
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1608
  • Product descriptionTropicamide
  • Packaging1unit
  • Price$28
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1608
  • Product descriptionTropicamide
  • Packaging10mM(in 1mL DMSO)
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1608
  • Product descriptionTropicamide
  • Packaging100mg
  • Price$53
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB1608
  • Product descriptionTropicamide
  • Packaging500mg
  • Price$76
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS444450
  • Product descriptionTropicamide 98%
  • Packaging100mg
  • Price$8
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS444450
  • Product descriptionTropicamide 98%
  • Packaging250mg
  • Price$13
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS444450
  • Product descriptionTropicamide 98%
  • Packaging1g
  • Price$19
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS444450
  • Product descriptionTropicamide 98%
  • Packaging5g
  • Price$76
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J95246 Tropicamide 25g $480 2021-12-16 Buy
Alfa Aesar J61132 Tropicamide, 99+% 1g $52.4 2023-06-20 Buy
Ambeed A130661 Tropicamide 98% 100mg $5 2021-12-16 Buy
Ambeed A130661 Tropicamide 98% 250mg $7 2021-12-16 Buy
Ambeed A130661 Tropicamide 98% 1g $11 2021-12-16 Buy
Ambeed A130661 Tropicamide 98% 5g $38 2021-12-16 Buy
Ambeed A130661 Tropicamide 98% 25g $180 2021-12-16 Buy
American Custom Chemicals Corporation API0004531 TROPICAMIDE 95.00% 1G $137.55 2021-12-16 Buy
ApexBio Technology B1608 Tropicamide 1unit $28 2021-12-16 Buy
ApexBio Technology B1608 Tropicamide 10mM(in 1mL DMSO) $50 2021-12-16 Buy
ApexBio Technology B1608 Tropicamide 100mg $53 2021-12-16 Buy
ApexBio Technology B1608 Tropicamide 500mg $76 2021-12-16 Buy
Arctom AS444450 Tropicamide 98% 100mg $8 2021-12-16 Buy
Arctom AS444450 Tropicamide 98% 250mg $13 2021-12-16 Buy
Arctom AS444450 Tropicamide 98% 1g $19 2021-12-16 Buy
Arctom AS444450 Tropicamide 98% 5g $76 2021-12-16 Buy

Properties

Melting point :98 °C
Boiling point :492.8±45.0 °C(Predicted)
Density :1.161±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 4.3 mg/mL
form :solid
pka :pKa 5.3 (Uncertain)
color :white
Water Solubility :0.2g/L(25 ºC)
λmax :254nm(HCl aq.)(lit.)
Merck :14,9780
InChI :InChI=1S/C17H20N2O2/c1-2-19(12-14-8-10-18-11-9-14)17(21)16(13-20)15-6-4-3-5-7-15/h3-11,16,20H,2,12-13H2,1H3
InChIKey :BGDKAVGWHJFAGW-UHFFFAOYSA-N
SMILES :C(CO)(C(=O)N(CC)CC1=CC=NC=C1)C1C=CC=CC=1
CAS DataBase Reference :1508-75-4(CAS DataBase Reference)
NIST Chemistry Reference :Tropicamide(1508-75-4)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H317 May cause an allergic skin reaction Sensitisation, Skin Category 1 Warning GHS hazard pictograms P261, P272, P280, P302+P352,P333+P313, P321, P363, P501
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Muscarinic receptors are G protein-coupled acetylcholine receptors that play diverse roles. Five subtypes (M1-5) have been identified, which preferentially couple to various effector systems based on their G protein interaction. Tropicamide is a muscarinic acetylcholine receptor (mAChR) antagonist (pKi = 7.2 in chicken heart) that displays 3-fold selectivity for M4. When applied as eye drops, it produces temporary mydriasis (pupil dilation; EC50 = 6 μg/ml) and cycloplegia (ciliary muscle paralysis; EC50 = 25 μg/ml). Tropicamide has been used to probe mAChR activity in a mouse model of fragile X syndrome.

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