Temsirolimus
- $46 - $1444
- Product name: Temsirolimus
- CAS: 162635-04-3
- MF: C56H87NO16
- MW: 1030.29
- EINECS:686-177-0
- MDL Number:MFCD00934421
- Synonyms:42-[3-hydroxy-2-(hydroxymethyl)-2-methylpropa;Temsirolimus(CCI-779);TEMSIROLIMUS;CCL-779;Rapamycin 42-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate;TeMsiroliMus (CCI-779, Torisel);rapaMycin 42-ester with 3-hydroxy-2-(hydroxyMethyl)-2-Methylpropionic acid;42-[3-Hydroxy-2-(hydroxymethyl)-2-methylpropanoate]rapamycin
54 prices
Selected condition:
Brand
- AK Scientific
- Alfa Aesar
- Ambeed
- ApexBio Technology
- Arctom
- AvaChem
- Axon Medchem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- Chem-Impex
- Crysdot
- CSNpharm
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 5mg
- 10mg
- 1mg
- 10
- 20mg
- 25mg
- 50mg
- 100mg
- 200mg
- 250mg
- 1g
- ManufacturerAK Scientific
- Product numberB622
- Product descriptionTemsirolimus
- Packaging1mg
- Price$49
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberB622
- Product descriptionTemsirolimus
- Packaging25mg
- Price$257
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ63654
- Product descriptionTemsirolimus 99+%
- Packaging25mg
- Price$318
- Updated2023-06-20
- Buy
- ManufacturerAlfa Aesar
- Product numberJ63654
- Product descriptionTemsirolimus 99+%
- Packaging50mg
- Price$585
- Updated2023-06-20
- Buy
- ManufacturerAlfa Aesar
- Product numberJ63654
- Product descriptionTemsirolimus 99+%
- Packaging100mg
- Price$776
- Updated2023-06-20
- Buy
- ManufacturerAmbeed
- Product numberA642622
- Product descriptionTemsirolimus 99%
- Packaging5mg
- Price$46
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA642622
- Product descriptionTemsirolimus 99%
- Packaging10mg
- Price$69
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA642622
- Product descriptionTemsirolimus 99%
- Packaging25mg
- Price$146
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA642622
- Product descriptionTemsirolimus 99%
- Packaging100mg
- Price$382
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA642622
- Product descriptionTemsirolimus 99%
- Packaging250mg
- Price$597
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA642622
- Product descriptionTemsirolimus 99%
- Packaging1g
- Price$1444
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8314
- Product descriptionTemsirolimus
- Packaging10mg
- Price$85
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60122
- Product descriptionTemsirolimus(CCI-779)
- Packaging20mg
- Price$288
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3349
- Product descriptionTemsirolimus
- Packaging5mg
- Price$49
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3349
- Product descriptionTemsirolimus
- Packaging10mg
- Price$59
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number3349
- Product descriptionTemsirolimus
- Packaging100mg
- Price$279
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | B622 | Temsirolimus | 1mg | $49 | 2021-12-16 | Buy |
AK Scientific | B622 | Temsirolimus | 25mg | $257 | 2021-12-16 | Buy |
Alfa Aesar | J63654 | Temsirolimus 99+% | 25mg | $318 | 2023-06-20 | Buy |
Alfa Aesar | J63654 | Temsirolimus 99+% | 50mg | $585 | 2023-06-20 | Buy |
Alfa Aesar | J63654 | Temsirolimus 99+% | 100mg | $776 | 2023-06-20 | Buy |
Ambeed | A642622 | Temsirolimus 99% | 5mg | $46 | 2021-12-16 | Buy |
Ambeed | A642622 | Temsirolimus 99% | 10mg | $69 | 2021-12-16 | Buy |
Ambeed | A642622 | Temsirolimus 99% | 25mg | $146 | 2021-12-16 | Buy |
Ambeed | A642622 | Temsirolimus 99% | 100mg | $382 | 2021-12-16 | Buy |
Ambeed | A642622 | Temsirolimus 99% | 250mg | $597 | 2021-12-16 | Buy |
Ambeed | A642622 | Temsirolimus 99% | 1g | $1444 | 2021-12-16 | Buy |
ApexBio Technology | A8314 | Temsirolimus | 10mg | $85 | 2021-12-16 | Buy |
Arctom | CFN60122 | Temsirolimus(CCI-779) | 20mg | $288 | 2021-12-16 | Buy |
AvaChem | 3349 | Temsirolimus | 5mg | $49 | 2021-12-16 | Buy |
AvaChem | 3349 | Temsirolimus | 10mg | $59 | 2021-12-16 | Buy |
AvaChem | 3349 | Temsirolimus | 100mg | $279 | 2021-12-16 | Buy |
Properties
Melting point :99-101°C
Boiling point :1048.4±75.0 °C(Predicted)
Density :1.21
Flash point :587.8℃
storage temp. :room temp
solubility :Soluble in chloroform, methanol.
pka :10.40±0.70(Predicted)
form :powder
color :white to off-white
Merck :14,9142
InChIKey :CBPNZQVSJQDFBE-FUXHJELOSA-N
Boiling point :1048.4±75.0 °C(Predicted)
Density :1.21
Flash point :587.8℃
storage temp. :room temp
solubility :Soluble in chloroform, methanol.
pka :10.40±0.70(Predicted)
form :powder
color :white to off-white
Merck :14,9142
InChIKey :CBPNZQVSJQDFBE-FUXHJELOSA-N
Safety Information
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Signal word: | Danger | |||||||||||||||||||||
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Precautionary statements: |
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Description
Rapamycin is an immunosuppressant that specifically interacts with the cytosolic FK-binding protein 12 to form a complex which inhibits the mammalian target of rapamycin (mTOR) pathway by directly binding to mTOR Complex 1. Temsirolimus is a dihydroxymethyl propionic acid ester of rapamycin with improved solubility that specifically inhibits mTOR signaling with a potency similar to that of rapamycin. Treatment with temsirolimus leads to cell cycle arrest in the G1 phase and also inhibition of tumor angiogenesis by reducing synthesis of VEGF. Temsirolimus demonstrates cytostatic activity in several xenograft models of human tumors in nude mice, including glioblastomas, prostate carcinoma, pancreatic, liver, and breast cancers, and medulloblastoma.Related product price
- 3-(4-Hydroxyphenyl)propionic acid
$10-2055.9 - Rapamycin
$9-6160 - CHLOROPHOSPHONAZO III
$55-992
Suppliers and manufacturers
Shanghai Daken Advanced Materials Co.,Ltd
Henan Tianfu Chemical Co.,Ltd.
Hangzhou FandaChem Co.,Ltd.
Shanghai Yingrui Biopharma Co., Ltd.
ATK CHEMICAL COMPANY LIMITED
Biochempartner