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ChemicalBook >> CAS DataBase List >> Temozolomide

Temozolomide

Temozolomide price.
  • $5 - $1208.7
  • Product name: Temozolomide
  • CAS: 85622-93-1
  • MF: C6H6N6O2
  • MW: 194.15
  • EINECS:630-358-9
  • MDL Number:MFCD00866492
  • Synonyms:4-methyl-5-oxo-2,3,4,6,8-pentazabicyclo[4.3.0]nona-2,7,9-triene-9-carboxamide;TEMOZOLOMIDE;nsc362856 ;Temozolimide;3,4-Dihydro-3-methyl-4-oxoimidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one, Methazolastone, M&B 39831, Temodal, Temodar,;TEMOZOLOMIDE HCL;Imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide, 3,4-dihydro-3-methyl-4-oxo-;3-Methyl-4-oxo-8-imidazolo[5,1-d][1,2,3,5]tetrazinecarboxamide, 8-Carbamoyl-3-methylimidazo[5,1-d]-1,2,3,5-tetrazin-4(3H)-one, 4-Methyl-5-oxo-2,3,4,6,8-pentazabicyclo[4.3.0]nona-2,7,9-triene-9-carboxamide
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  • 10mM(in 1mL DMSO)
  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-T0072-M250
  • Product descriptionTemozolomide ≥98%(HPLC)
  • Packaging250mg
  • Price$341
  • Updated2021-12-16
  • Buy
  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-T0072-G001
  • Product descriptionTemozolomide ≥98%(HPLC)
  • Packaging1g
  • Price$882
  • Updated2021-12-16
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  • ManufacturerAHH
  • Product numberAPI-1246
  • Product descriptionTemozolomide 98%
  • Packaging1g
  • Price$680
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA137834
  • Product description3-Methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide 98+%
  • Packaging50mg
  • Price$5
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA137834
  • Product description3-Methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide 98+%
  • Packaging100mg
  • Price$9
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA137834
  • Product description3-Methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide 98+%
  • Packaging250mg
  • Price$13
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA137834
  • Product description3-Methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide 98+%
  • Packaging1g
  • Price$30
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA137834
  • Product description3-Methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide 98+%
  • Packaging5g
  • Price$100
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA137834
  • Product description3-Methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide 98+%
  • Packaging25g
  • Price$348
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB1399
  • Product descriptionTemozolomide
  • Packaging10mg
  • Price$50
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB1399
  • Product descriptionTemozolomide
  • Packaging10mM(in 1mL DMSO)
  • Price$50
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB1399
  • Product descriptionTemozolomide
  • Packaging50mg
  • Price$70
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberOR912057
  • Product descriptionTemozolomide 98%
  • Packaging1g
  • Price$40
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberOR912057
  • Product descriptionTemozolomide 98%
  • Packaging5g
  • Price$115
  • Updated2021-12-16
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  • ManufacturerArctom
  • Product numberAS031848
  • Product description3-Methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide ≥98%
  • Packaging50mg
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS031848
  • Product description3-Methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide ≥98%
  • Packaging100mg
  • Price$9
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences CDX-T0072-M250 Temozolomide ≥98%(HPLC) 250mg $341 2021-12-16 Buy
Adipogen Life Sciences CDX-T0072-G001 Temozolomide ≥98%(HPLC) 1g $882 2021-12-16 Buy
AHH API-1246 Temozolomide 98% 1g $680 2021-12-16 Buy
Ambeed A137834 3-Methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide 98+% 50mg $5 2021-12-16 Buy
Ambeed A137834 3-Methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide 98+% 100mg $9 2021-12-16 Buy
Ambeed A137834 3-Methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide 98+% 250mg $13 2021-12-16 Buy
Ambeed A137834 3-Methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide 98+% 1g $30 2021-12-16 Buy
Ambeed A137834 3-Methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide 98+% 5g $100 2021-12-16 Buy
Ambeed A137834 3-Methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide 98+% 25g $348 2021-12-16 Buy
ApexBio Technology B1399 Temozolomide 10mg $50 2021-12-16 Buy
ApexBio Technology B1399 Temozolomide 10mM(in 1mL DMSO) $50 2021-12-16 Buy
ApexBio Technology B1399 Temozolomide 50mg $70 2021-12-16 Buy
Apolloscientific OR912057 Temozolomide 98% 1g $40 2021-12-16 Buy
Apolloscientific OR912057 Temozolomide 98% 5g $115 2021-12-16 Buy
Arctom AS031848 3-Methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide ≥98% 50mg $5 2021-12-16 Buy
Arctom AS031848 3-Methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide ≥98% 100mg $9 2021-12-16 Buy

Properties

Melting point :212°C dec.
Boiling point :526.6±42.0 °C(Predicted)
Density :1.97±0.1 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble10mg/mL, clear
pka :14.77±0.20(Predicted)
form :powder
color :white to light brown
Merck :14,9139
Stability :Stable for 2 years as supplied. Solutions in DMSO may be stored at -20° for up to 3 months.
InChIKey :BPEGJWRSRHCHSN-UHFFFAOYSA-N
CAS DataBase Reference :85622-93-1(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H340 May cause genetic defects Germ cell mutagenicity Category 1A, 1B Danger GHS hazard pictograms
H350 May cause cancer Carcinogenicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

Temozolomide (TMZ) is an imidazotetrazine that is converted to a compound capable of alkylating DNA, thus interfering with DNA replication and leading to cytotoxicity in proliferating cells. TMZ is rapidly and completely absorbed from the gastrointestinal tract after oral administration and readily crosses the blood-brain barrier. It is effective in a variety of types of cancer, including aggressive brain cancers.

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