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ChemicalBook >> CAS DataBase List >> (S)-MEPHENYTOIN

(S)-MEPHENYTOIN

(S)-MEPHENYTOIN price.
  • $90 - $850
  • Product name: (S)-MEPHENYTOIN
  • CAS: 50-12-4
  • MF: C12H14N2O2
  • MW: 218.25
  • EINECS:200-012-8
  • MDL Number:MFCD00270025
  • Synonyms:(S)-(+)-5-ETHYL-3-METHYL-5-PHENYL-2,4-IMIDAZOLIDINEDIONE;(S)-(+)-5-ETHYL-3-METHYL-5-PHENYLHYDANTOIN;(S)-5-ETHYL-3-METHYL-5-PHENYLHYDANTOIN;(S)-(+)-MEPHENYTOIN;(+/-)-5-ETHYL-3-METHYL-5-PHENYL-2,4-IMIDAZOLIDINEDIONE;(+/-)-5-ETHYL-3-METHYL-5-PHENYLHYDANTOIN;(+/-)-MEPHENYTOIN;MEPHENYTOIN
8 prices
Selected condition：
Brand
  • American Custom Chemicals Corporation
  • ChemScene
  • Medical Isotopes, Inc.
  • Tocris
  • TRC
  • Usbiological
Package
  • 10
  • 5mg
  • 10MG
  • 25mg
  • 50mg
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003306
  • Product descriptionMESANTOIN 95.00%
  • Packaging10MG
  • Price$280.35
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-4793
  • Product descriptionMephenytoin 99.68%
  • Packaging10mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-4793
  • Product descriptionMephenytoin 99.68%
  • Packaging50mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number65906
  • Product descriptionrac-Mephenytoin
  • Packaging10mg
  • Price$675
  • Updated2021-12-16
  • Buy
  • ManufacturerMedical Isotopes, Inc.
  • Product number65906
  • Product descriptionrac-Mephenytoin
  • Packaging25mg
  • Price$850
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number3276
  • Product descriptionMephenytoin ≥98%(HPLC)
  • Packaging10
  • Price$282
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberM224985
  • Product descriptionrac-Mephenytoin
  • Packaging5mg
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number255787
  • Product descriptionMephenytoin
  • Packaging10mg
  • Price$545
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation API0003306 MESANTOIN 95.00% 10MG $280.35 2021-12-16 Buy
ChemScene CS-4793 Mephenytoin 99.68% 10mg $150 2021-12-16 Buy
ChemScene CS-4793 Mephenytoin 99.68% 50mg $250 2021-12-16 Buy
Medical Isotopes, Inc. 65906 rac-Mephenytoin 10mg $675 2021-12-16 Buy
Medical Isotopes, Inc. 65906 rac-Mephenytoin 25mg $850 2021-12-16 Buy
Tocris 3276 Mephenytoin ≥98%(HPLC) 10 $282 2021-12-16 Buy
TRC M224985 rac-Mephenytoin 5mg $90 2021-12-16 Buy
Usbiological 255787 Mephenytoin 10mg $545 2021-12-16 Buy

Properties

Melting point :135-138 °C
Boiling point :358.94°C (rough estimate)
Density :1.154±0.06 g/cm3 (20 ºC 760 Torr)
refractive index :1.6660 (estimate)
storage temp. :2-8°C
solubility :DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
form :solid
pka :pKa 8.1 (Uncertain)
color :off-white
CAS DataBase Reference :50-12-4(CAS DataBase Reference)
EPA Substance Registry System :Mephenytoin (50-12-4)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Mephenytoin is N-methylated at position 3 with an ethyl group replacing one of the phenyl substituents at position 5. It is indicated for focal and jacksonian seizures in patients refractory to less toxic AEDs. Mephenytoin produces more sedation than phenytoin and should be used only when safer drugs have failed, because it is associated with an increased incidence of serious toxicities, such as severe rash, agranulocytosis, and hepatitis. Its N-desmethyl metabolite, 5-phenyl- 5-ethylhydantoin, contributes to both efficacy and toxicity for mephenytoin. The drug is no longer commercially available inside but is still available outside the United States.

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