OF-1
- $49 - $779
- Product name: OF-1
- CAS: 919973-83-4
- MF: C17H18BrN3O4S
- MW: 440.31
- EINECS:604-604-1
- MDL Number:MFCD26964046
- Synonyms:OF-1;4-bromo-N-(6-methoxy-1,3-dimethyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)-2-methylbenzenesulfonamide;4-Bromo-N-(2,3-dihydro-6-methoxy-1,3-dimethyl-2-oxo-1H-benzimidazol-5-yl)-2-methyl-benzenesulfonamide;OF-1 USP/EP/BP;Benzenesulfonamide, 4-bromo-N-(2,3-dihydro-6-methoxy-1,3-dimethyl-2-oxo-1H-benzimidazol-5-yl)-2-methyl-;4-bromo-N-(6-methoxy-1,3-dimethyl-2-oxobenzimidazol-5-yl)-2-methylbenzenesulfonamide;OF-1;OF1;CS-1634
22 prices
Selected condition:
Brand
- AK Scientific
- Ambeed
- ApexBio Technology
- Cayman Chemical
- ChemScene
- DC Chemicals
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- TRC
Package
- 10
- 1mg
- 5mg
- 10mg
- 25mg
- 50
- 100mg
- 10mM(in 1mL DMSO)
- 50mg
- ManufacturerAK Scientific
- Product numberSYN5650
- Product descriptionSGCOF-1
- Packaging50mg
- Price$547
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA525019
- Product descriptionOF-1 98+%
- Packaging50mg
- Price$303
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA525019
- Product descriptionOF-1 98+%
- Packaging100mg
- Price$394
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4895
- Product descriptionOF-1
- Packaging5mg
- Price$68
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4895
- Product descriptionOF-1
- Packaging10mM(in 1mL DMSO)
- Price$100
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4895
- Product descriptionOF-1
- Packaging25mg
- Price$243
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB4895
- Product descriptionOF-1
- Packaging100mg
- Price$593
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17124
- Product descriptionOF-1 ≥98%
- Packaging1mg
- Price$49
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17124
- Product descriptionOF-1 ≥98%
- Packaging5mg
- Price$109
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17124
- Product descriptionOF-1 ≥98%
- Packaging10mg
- Price$190
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17124
- Product descriptionOF-1 ≥98%
- Packaging25mg
- Price$416
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-3687
- Product descriptionOF-1 98.09%
- Packaging5mg
- Price$102
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3687
- Product descriptionOF-1 98.09%
- Packaging10mg
- Price$162
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-3687
- Product descriptionOF-1 98.09%
- Packaging50mg
- Price$648
- Updated2021-12-16
- Buy
- ManufacturerDC Chemicals
- Product numberDC7850
- Product descriptionOF-1 >98%
- Packaging100mg
- Price$500
- Updated2021-12-16
- Buy
- ManufacturerMedical Isotopes, Inc.
- Product number54910
- Product description4-Bromo-N-(2,3-dihydro-6-methoxy-1,3-dimethyl-2-oxo-1H-benzimidazol-5-yl)-2-methylbenzenesulfonamide
- Packaging10mg
- Price$650
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | SYN5650 | SGCOF-1 | 50mg | $547 | 2021-12-16 | Buy |
Ambeed | A525019 | OF-1 98+% | 50mg | $303 | 2021-12-16 | Buy |
Ambeed | A525019 | OF-1 98+% | 100mg | $394 | 2021-12-16 | Buy |
ApexBio Technology | B4895 | OF-1 | 5mg | $68 | 2021-12-16 | Buy |
ApexBio Technology | B4895 | OF-1 | 10mM(in 1mL DMSO) | $100 | 2021-12-16 | Buy |
ApexBio Technology | B4895 | OF-1 | 25mg | $243 | 2021-12-16 | Buy |
ApexBio Technology | B4895 | OF-1 | 100mg | $593 | 2021-12-16 | Buy |
Cayman Chemical | 17124 | OF-1 ≥98% | 1mg | $49 | 2024-03-01 | Buy |
Cayman Chemical | 17124 | OF-1 ≥98% | 5mg | $109 | 2024-03-01 | Buy |
Cayman Chemical | 17124 | OF-1 ≥98% | 10mg | $190 | 2024-03-01 | Buy |
Cayman Chemical | 17124 | OF-1 ≥98% | 25mg | $416 | 2024-03-01 | Buy |
ChemScene | CS-3687 | OF-1 98.09% | 5mg | $102 | 2021-12-16 | Buy |
ChemScene | CS-3687 | OF-1 98.09% | 10mg | $162 | 2021-12-16 | Buy |
ChemScene | CS-3687 | OF-1 98.09% | 50mg | $648 | 2021-12-16 | Buy |
DC Chemicals | DC7850 | OF-1 >98% | 100mg | $500 | 2021-12-16 | Buy |
Medical Isotopes, Inc. | 54910 | 4-Bromo-N-(2,3-dihydro-6-methoxy-1,3-dimethyl-2-oxo-1H-benzimidazol-5-yl)-2-methylbenzenesulfonamide | 10mg | $650 | 2021-12-16 | Buy |
Properties
Boiling point :573.8±60.0 °C(Predicted)
Density :1.557±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble5mg/mL, clear (warmed)
pka :9.44±0.20(Predicted)
form :powder
color :white to beige
Density :1.557±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: soluble5mg/mL, clear (warmed)
pka :9.44±0.20(Predicted)
form :powder
color :white to beige
Safety Information
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Signal word: | Danger | |||||||||||||||||||||
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Description
OF-1 is a chemical probe for the bromodomains of the Bromodomain and PHD Finger-containing (BRPF) family of proteins. It binds BRPF1B, BRPF2, and BRPF3 with Kd values of 0.1, 0.5, and 2.4 μM, respectively, as determined by isothermal titration calorimetry. OF-1 increases thermal stability of full length BRPF1B at 1 μM, in the cellular thermal shift assay. It also demonstrates accelerated fluorescence recovery after photobleaching (FRAP) at 5 μM in the BRPF2 FRAP assay. OF-1 shows modest general cytotoxicity. See the Structural Genomics Consortium (SGC) website for further information.Related product price
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