Nintedanib esylate
|
- $7 - $2233.8
- Product name: Nintedanib esylate
- CAS: 656247-18-6
- MF: C33H39N5O7S
- MW: 649.76
- EINECS:
- MDL Number:MFCD26142360
- Synonyms:(3Z)-2,3-Dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-1H-indole-6-carboxylic acid methyl ester ethanesulfonate ;BIBF 1120 esylate;BIBF-1120 esylate;BIBF1120/nintedanib ethanesulfonate salt;Trinidad Neeb esylate;Intedanib ethanesulfonate;Nintedanib ethanesulfonate salt;Trinidad Neeb ethanesulfonate
35 prices
Selected condition：
Brand
- AK Scientific
- Ambeed
- American Custom Chemicals Corporation
- Biorbyt Ltd
- Biosynth Carbosynth
- Chemenu
- ChemScene
- Crysdot
- DC Chemicals
- Labseeker
- Matrix Scientific
- TRC
Package
- 5MG
- 10mg
- 25mg
- 50mg
- 100mg
- 200mg
- 250mg
- 500mg
- 1g
- 2g
- 5g
- 10g
- ManufacturerAK Scientific
- Product numberJ51091
- Product descriptionNintedanibesylate
- Packaging1g
- Price$178
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number9942AL
- Product descriptionNintedanibesylate
- Packaging25mg
- Price$67.2
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA160216
- Product description(Z)-Methyl3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylateethanesulfonate 98+%
- Packaging100mg
- Price$7
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA160216
- Product description(Z)-Methyl3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylateethanesulfonate 98+%
- Packaging250mg
- Price$14
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA160216
- Product description(Z)-Methyl3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylateethanesulfonate 98+%
- Packaging5g
- Price$136
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCHM0292797
- Product description(3Z)-2,3-DIHYDRO-3-[[[4-[METHYL[2-(4-METHYL-1-PIPERAZINYL)ACETYL]AMINO]PHENYL]AMINO]PHENYLMETHYLENE]-2-OXO-1H-INDOLE-6-CARBOXYLIC ACID METHYL ESTER ETHANESULFONATE 95.00%
- Packaging5MG
- Price$497.93
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180030
- Product descriptionNintedanib, Ethanesulfonate Salt >99%
- Packaging5G
- Price$2233.8
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180030
- Product descriptionNintedanib, Ethanesulfonate Salt >99%
- Packaging2g
- Price$1174.7
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180030
- Product descriptionNintedanib, Ethanesulfonate Salt >99%
- Packaging1g
- Price$705.5
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180030
- Product descriptionNintedanib, Ethanesulfonate Salt >99%
- Packaging500mg
- Price$671.5
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180030
- Product descriptionNintedanib, Ethanesulfonate Salt >99%
- Packaging200mg
- Price$433.5
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180030
- Product descriptionNintedanib, Ethanesulfonate Salt >99%
- Packaging100mg
- Price$414.8
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180030
- Product descriptionNintedanib, Ethanesulfonate Salt >99%
- Packaging50mg
- Price$357
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb180030
- Product descriptionNintedanib, Ethanesulfonate Salt >99%
- Packaging25mg
- Price$304.3
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFD71497
- Product descriptionNintedanib ethanesulfonate
- Packaging25mg
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFD71497
- Product descriptionNintedanib ethanesulfonate
- Packaging50mg
- Price$100
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | J51091 | Nintedanibesylate | 1g | $178 | 2021-12-16 | Buy |
| AK Scientific | 9942AL | Nintedanibesylate | 25mg | $67.2 | 2021-12-16 | Buy |
| Ambeed | A160216 | (Z)-Methyl3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylateethanesulfonate 98+% | 100mg | $7 | 2021-12-16 | Buy |
| Ambeed | A160216 | (Z)-Methyl3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylateethanesulfonate 98+% | 250mg | $14 | 2021-12-16 | Buy |
| Ambeed | A160216 | (Z)-Methyl3-(((4-(N-methyl-2-(4-methylpiperazin-1-yl)acetamido)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxylateethanesulfonate 98+% | 5g | $136 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | CHM0292797 | (3Z)-2,3-DIHYDRO-3-[[[4-[METHYL[2-(4-METHYL-1-PIPERAZINYL)ACETYL]AMINO]PHENYL]AMINO]PHENYLMETHYLENE]-2-OXO-1H-INDOLE-6-CARBOXYLIC ACID METHYL ESTER ETHANESULFONATE 95.00% | 5MG | $497.93 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180030 | Nintedanib, Ethanesulfonate Salt >99% | 5G | $2233.8 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180030 | Nintedanib, Ethanesulfonate Salt >99% | 2g | $1174.7 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180030 | Nintedanib, Ethanesulfonate Salt >99% | 1g | $705.5 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180030 | Nintedanib, Ethanesulfonate Salt >99% | 500mg | $671.5 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180030 | Nintedanib, Ethanesulfonate Salt >99% | 200mg | $433.5 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180030 | Nintedanib, Ethanesulfonate Salt >99% | 100mg | $414.8 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180030 | Nintedanib, Ethanesulfonate Salt >99% | 50mg | $357 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb180030 | Nintedanib, Ethanesulfonate Salt >99% | 25mg | $304.3 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD71497 | Nintedanib ethanesulfonate | 25mg | $60 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FD71497 | Nintedanib ethanesulfonate | 50mg | $100 | 2021-12-16 | Buy |
Properties
Melting point :>233°C (dec.)
storage temp. :-20°C Freezer
solubility :DMSO (Slightly), Methanol (Slightly)
form :Yellow solid.
color :Light Yellow to Yellow
InChIKey :MMMVNAGRWOJNMW-FJBFXRHMSA-N
SMILES :S(O)(=O)(=O)CC.C(/C1C=CC=CC=1)(=C1\C(NC2=CC(C(=O)OC)=CC=C\12)=O)\NC1C=CC(N(C)C(=O)CN2CCN(C)CC2)=CC=1
storage temp. :-20°C Freezer
solubility :DMSO (Slightly), Methanol (Slightly)
form :Yellow solid.
color :Light Yellow to Yellow
InChIKey :MMMVNAGRWOJNMW-FJBFXRHMSA-N
SMILES :S(O)(=O)(=O)CC.C(/C1C=CC=CC=1)(=C1\C(NC2=CC(C(=O)OC)=CC=C\12)=O)\NC1C=CC(N(C)C(=O)CN2CCN(C)CC2)=CC=1
Safety Information
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| Signal word: | Warning | |||||||||||||||||||||||||||||||||||
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Description
Nintedanib esylate is a potent, oral triple angiokinase inhibitor developed by Boehringer Ingelheim that targets proangiogenic and pro-fibrotic pathways mediated by the vascular endothelial growth factor receptor, fibroblast growth factor receptor and plateletderived growth factor receptor families, as well as Src and Flt-3 kinases. It was approved for the treatment of idiopathic pulmonary fibrosis (IPF), a condition in which the lungs become progressively scarred over time, by the US FDA in October 2014 and by the EMA in January 2015. The FDA granted nintedanib esylate fast-track, priority review, orphan product, and breakthrough designations. The drug was also approved by the EMA in November 2014 for treatment of non-small cell lung cancer in combination with docetaxel after first-line chemotherapy.More related product prices
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$50-641
Suppliers and manufacturers
Shanghai Daken Advanced Materials Co.,Ltd
Beijing Cooperate Pharmaceutical Co.,Ltd
Shanghai Bojing Chemical Co.,Ltd.
Henan Tianfu Chemical Co.,Ltd.
Nanjing ChemLin Chemical Industry Co., Ltd.
