Nilotinib
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- $25 - $960
- Product name: Nilotinib
- CAS: 641571-10-0
- MF: C28H22F3N7O
- MW: 529.52
- EINECS:700-544-5
- MDL Number:MFCD09833716
- Synonyms:Nilotinib;Benzamide, 4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-;Nilotinib(TINIBS );4-Methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)-N-(5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl)benzamide;4-methyl-N-(3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl)-3-(4-(pyridin-3-yl)pyrimidin-2-ylamino)benzamide;Nilotinib & its intermediates;Nilotinib for research;Nilotinib(AMN 107)
39 prices
Selected condition：
Brand
- AccelPharmtech
- Adipogen Life Sciences
- AK Scientific
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- AvaChem
- Axon Medchem
- Biorbyt Ltd
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- TRC
- Usbiological
Package
- 1mg
- 5MG
- 10mg
- 20mg
- 25mg
- 50mg
- 100mg
- 200mg
- 250mg
- 500mg
- 1g
- 2g
- 5g
- 10G
- 25g
- ManufacturerAccelPharmtech
- Product numberAT8434
- Product descriptionNilotinib 99.00%
- Packaging10G
- Price$180
- Updated2021-12-16
- Buy
- ManufacturerAdipogen Life Sciences
- Product numberSYN-1057-M010
- Product descriptionNilotinib ≥95%
- Packaging10mg
- Price$108
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ51374
- Product descriptionNilotinib
- Packaging5g
- Price$190
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ51374
- Product descriptionNilotinib
- Packaging10g
- Price$300
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberV0705
- Product descriptionNilotinib
- Packaging25g
- Price$801
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ11241
- Product descriptionNilotinib
- Packaging5g
- Price$960
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberRDL0007002
- Product descriptionNILOTINIB-D6 95.00%
- Packaging5MG
- Price$499.79
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8232
- Product descriptionNilotinib(AMN-107)
- Packaging100mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8232
- Product descriptionNilotinib(AMN-107)
- Packaging500mg
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN60185
- Product descriptionNilotinib(AMN-107) ≥98%
- Packaging20mg
- Price$50
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2162
- Product descriptionNilotinib
- Packaging100mg
- Price$35
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2162
- Product descriptionNilotinib
- Packaging250mg
- Price$45
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2162
- Product descriptionNilotinib
- Packaging1g
- Price$115
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2162
- Product descriptionNilotinib
- Packaging5g
- Price$375
- Updated2021-12-16
- Buy
- ManufacturerAxon Medchem
- Product numberAxon1396
- Product descriptionNilotinib-AMN107|Tasigna 99%
- Packaging5mg
- Price$55
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb546000
- Product descriptionNilotinib >98%
- Packaging10mg
- Price$119
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AccelPharmtech | AT8434 | Nilotinib 99.00% | 10G | $180 | 2021-12-16 | Buy |
| Adipogen Life Sciences | SYN-1057-M010 | Nilotinib ≥95% | 10mg | $108 | 2021-12-16 | Buy |
| AK Scientific | J51374 | Nilotinib | 5g | $190 | 2021-12-16 | Buy |
| AK Scientific | J51374 | Nilotinib | 10g | $300 | 2021-12-16 | Buy |
| AK Scientific | V0705 | Nilotinib | 25g | $801 | 2021-12-16 | Buy |
| AK Scientific | J11241 | Nilotinib | 5g | $960 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | RDL0007002 | NILOTINIB-D6 95.00% | 5MG | $499.79 | 2021-12-16 | Buy |
| ApexBio Technology | A8232 | Nilotinib(AMN-107) | 100mg | $50 | 2021-12-16 | Buy |
| ApexBio Technology | A8232 | Nilotinib(AMN-107) | 500mg | $120 | 2021-12-16 | Buy |
| Arctom | CFN60185 | Nilotinib(AMN-107) ≥98% | 20mg | $50 | 2021-12-16 | Buy |
| AvaChem | 2162 | Nilotinib | 100mg | $35 | 2021-12-16 | Buy |
| AvaChem | 2162 | Nilotinib | 250mg | $45 | 2021-12-16 | Buy |
| AvaChem | 2162 | Nilotinib | 1g | $115 | 2021-12-16 | Buy |
| AvaChem | 2162 | Nilotinib | 5g | $375 | 2021-12-16 | Buy |
| Axon Medchem | Axon1396 | Nilotinib-AMN107|Tasigna 99% | 5mg | $55 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb546000 | Nilotinib >98% | 10mg | $119 | 2021-12-16 | Buy |
Properties
Melting point :231-233 °C
Density :1.36
storage temp. :-20°C Freezer
solubility :Soluble in DMSO (up to 50 mg/ml)
form :Beige powder.
color :Off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
InChIKey :HHZIURLSWUIHRB-UHFFFAOYSA-N
SMILES :N1(C=C(C)N=C1)C1C=C(C=C(C=1)NC(=O)C1C=CC(C)=C(NC2=NC=CC(C3=CC=CN=C3)=N2)C=1)C(F)(F)F
CAS DataBase Reference :641571-10-0(CAS DataBase Reference)
Density :1.36
storage temp. :-20°C Freezer
solubility :Soluble in DMSO (up to 50 mg/ml)
form :Beige powder.
color :Off-white
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 1 month.
InChIKey :HHZIURLSWUIHRB-UHFFFAOYSA-N
SMILES :N1(C=C(C)N=C1)C1C=C(C=C(C=1)NC(=O)C1C=CC(C)=C(NC2=NC=CC(C3=CC=CN=C3)=N2)C=1)C(F)(F)F
CAS DataBase Reference :641571-10-0(CAS DataBase Reference)
Safety Information
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| Signal word: | Warning | ||||||||||||||||||||||||||||
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Description
Nilotinib is the other second-generation Abl kinase inhibitor approved for treatment of patients with CML. Nilotinib has increased affinity for the Abl kinase compared with imatinib, binding with an improved topologic fit to the kinase site in its inactive form.Nilotinib is active in chronic and accelerated phase CML patients who have developed resistance to imatinib. As with dasatinib, nilotinib was compared with imatinib in a phase III randomized trial as initial therapy for chronic phase CML patients, with nilotinib achieving higher rates of complete cytogenetic and major molecular responses and with fewer cases of disease progression or clonal evolution in the nilotinib-treated cohorts. Survival outcomes were similar in all arms. Common adverse events with nilotinib included rash, gastrointestinal disturbances (nausea, vomiting, diarrhea), neutropenia, and thrombocytopenia. Pleural effusion and peripheral edema are less common than with dasatinib. In addition, QT prolongation and a risk of pancreatitis are serious side effects of nilotinib.More related product prices
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Suppliers and manufacturers
AFINE CHEMICALS LIMITED
TAIZHOU YUXIN BIOTECHNOLOGY CO,.LTD
Frapp's ChemicalNFTZ Co., Ltd.
Capot Chemical Co.,Ltd.
Beijing Cooperate Pharmaceutical Co.,Ltd
Chembon Pharmaceutical Co., Ltd.
