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ChemicalBook >> CAS DataBase List >> Mc-Val-Cit-PABC-PNP

Mc-Val-Cit-PABC-PNP

Mc-Val-Cit-PABC-PNP price.
  • $11 - $2680
  • Product name: Mc-Val-Cit-PABC-PNP
  • CAS: 159857-81-5
  • MF: C35H43N7O11
  • MW: 737.76
  • EINECS:
  • MDL Number:MFCD22200431
  • Synonyms:Maleimidocaproyl-L-valine-L-citrulline-p-aminobenzyl alcohol p-nitrophenyl carbonate Mc-Val-Cit-PABC-PNP;L-OrnithinaMide, N-[6-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-1-oxohexyl]-L-valyl-N5-(aMinocarbonyl)-N-[4-[[[(4-nitrophenoxy)carbonyl]oxy]Methyl]phenyl]-;Maleimidocaproyl-L-valine-L-citrulline-p-aminobenzyl alcohol p-nitrophenyl carbonate;MC-Val-Cit-PAB-PNP (ADC peptide linker);4-((S)-2-((S)-2-(6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamido)-3-methylbutanamido)-5-ureidopentanamido)benzyl 4-nitrophenyl carbonate;MC-VC-PAB-PNP,Mc-Val-Cit-PABC-PNP;MC-VAL-CIT-PABC-PNP;MC-VC-PAB-PNP;MC-VAL-CIT-PAB-PNB;MC-VAL-CIT-PAB-PNP;[4-[[(2S)-5-(carbamoylamino)-2-[[(2S)-2-[6-(2,5-dioxopyrrol-1-yl)hexanoylamino]-3-methylbutanoyl]amino]pentanoyl]amino]phenyl]methyl (4-nitrophenyl) carbonate
25 prices
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Brand
  • Acrotein
  • AK Scientific
  • Ambeed
  • ApexBio Technology
  • BroadPharm
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • Iris Biotech GmbH
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • 0.5g
  • 1g
  • 5g
  • ManufacturerAcrotein
  • Product numberNA-1389
  • Product descriptionMc-Val-Cit-PAB-PNP 97%
  • Packaging0.5g
  • Price$907.5
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number3805AH
  • Product descriptionMc-Val-Cit-PABC-PNP
  • Packaging100mg
  • Price$594
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA133919
  • Product description4-((S)-2-((S)-2-(6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamido)-3-methylbutanamido)-5-ureidopentanamido)benzyl(4-nitrophenyl)carbonate 98+%
  • Packaging1mg
  • Price$11
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA133919
  • Product description4-((S)-2-((S)-2-(6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamido)-3-methylbutanamido)-5-ureidopentanamido)benzyl(4-nitrophenyl)carbonate 98+%
  • Packaging5mg
  • Price$23
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA133919
  • Product description4-((S)-2-((S)-2-(6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamido)-3-methylbutanamido)-5-ureidopentanamido)benzyl(4-nitrophenyl)carbonate 98+%
  • Packaging10mg
  • Price$34
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA133919
  • Product description4-((S)-2-((S)-2-(6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamido)-3-methylbutanamido)-5-ureidopentanamido)benzyl(4-nitrophenyl)carbonate 98+%
  • Packaging25mg
  • Price$57
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA133919
  • Product description4-((S)-2-((S)-2-(6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamido)-3-methylbutanamido)-5-ureidopentanamido)benzyl(4-nitrophenyl)carbonate 98+%
  • Packaging100mg
  • Price$130
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA133919
  • Product description4-((S)-2-((S)-2-(6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamido)-3-methylbutanamido)-5-ureidopentanamido)benzyl(4-nitrophenyl)carbonate 98+%
  • Packaging250mg
  • Price$225
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA133919
  • Product description4-((S)-2-((S)-2-(6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamido)-3-methylbutanamido)-5-ureidopentanamido)benzyl(4-nitrophenyl)carbonate 98+%
  • Packaging1g
  • Price$656
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB1003
  • Product descriptionMc-Val-Cit-PABC-PNP
  • Packaging10mg
  • Price$200
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB1003
  • Product descriptionMc-Val-Cit-PABC-PNP
  • Packaging50mg
  • Price$618
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberB1003
  • Product descriptionMc-Val-Cit-PABC-PNP
  • Packaging100mg
  • Price$940
  • Updated2021-12-16
  • Buy
  • ManufacturerBroadPharm
  • Product numberBP-23292
  • Product descriptionMC-Val-Cit-PAB-PNP 95%
  • Packaging1g
  • Price$1180
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number23881
  • Product descriptionMc-Val-Cit-PABC-PNP ≥98%
  • Packaging1mg
  • Price$32
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number23881
  • Product descriptionMc-Val-Cit-PABC-PNP ≥98%
  • Packaging5mg
  • Price$139
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number23881
  • Product descriptionMc-Val-Cit-PABC-PNP ≥98%
  • Packaging10mg
  • Price$243
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Acrotein NA-1389 Mc-Val-Cit-PAB-PNP 97% 0.5g $907.5 2021-12-16 Buy
AK Scientific 3805AH Mc-Val-Cit-PABC-PNP 100mg $594 2021-12-16 Buy
Ambeed A133919 4-((S)-2-((S)-2-(6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamido)-3-methylbutanamido)-5-ureidopentanamido)benzyl(4-nitrophenyl)carbonate 98+% 1mg $11 2021-12-16 Buy
Ambeed A133919 4-((S)-2-((S)-2-(6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamido)-3-methylbutanamido)-5-ureidopentanamido)benzyl(4-nitrophenyl)carbonate 98+% 5mg $23 2021-12-16 Buy
Ambeed A133919 4-((S)-2-((S)-2-(6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamido)-3-methylbutanamido)-5-ureidopentanamido)benzyl(4-nitrophenyl)carbonate 98+% 10mg $34 2021-12-16 Buy
Ambeed A133919 4-((S)-2-((S)-2-(6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamido)-3-methylbutanamido)-5-ureidopentanamido)benzyl(4-nitrophenyl)carbonate 98+% 25mg $57 2021-12-16 Buy
Ambeed A133919 4-((S)-2-((S)-2-(6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamido)-3-methylbutanamido)-5-ureidopentanamido)benzyl(4-nitrophenyl)carbonate 98+% 100mg $130 2021-12-16 Buy
Ambeed A133919 4-((S)-2-((S)-2-(6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamido)-3-methylbutanamido)-5-ureidopentanamido)benzyl(4-nitrophenyl)carbonate 98+% 250mg $225 2021-12-16 Buy
Ambeed A133919 4-((S)-2-((S)-2-(6-(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamido)-3-methylbutanamido)-5-ureidopentanamido)benzyl(4-nitrophenyl)carbonate 98+% 1g $656 2021-12-16 Buy
ApexBio Technology B1003 Mc-Val-Cit-PABC-PNP 10mg $200 2021-12-16 Buy
ApexBio Technology B1003 Mc-Val-Cit-PABC-PNP 50mg $618 2021-12-16 Buy
ApexBio Technology B1003 Mc-Val-Cit-PABC-PNP 100mg $940 2021-12-16 Buy
BroadPharm BP-23292 MC-Val-Cit-PAB-PNP 95% 1g $1180 2021-12-16 Buy
Cayman Chemical 23881 Mc-Val-Cit-PABC-PNP ≥98% 1mg $32 2024-03-01 Buy
Cayman Chemical 23881 Mc-Val-Cit-PABC-PNP ≥98% 5mg $139 2024-03-01 Buy
Cayman Chemical 23881 Mc-Val-Cit-PABC-PNP ≥98% 10mg $243 2024-03-01 Buy

Properties

Boiling point :1034.5±65.0 °C(Predicted)
Density :1.338±0.06 g/cm3(Predicted)
storage temp. :under inert gas (nitrogen or Argon) at 2-8°C
solubility :DMF: 25 mg/ml; DMSO: 20 mg/ml; DMSO:PBS(pH 7.2) (1:4): 0.20 mg/ml
form :A crystalline solid
pka :13.24±0.70(Predicted)
color :Off-white to light yellow
InChIKey :UQRQGHMQKAXOTE-DHIFEGFHSA-N
SMILES :C(N)(=O)[C@H](CCCNC(N)=O)N(C(=O)[C@H](C(C)C)NC(=O)CCCCCN1C(=O)C=CC1=O)C1=CC=C(COC(OC2=CC=C([N+]([O-])=O)C=C2)=O)C=C1

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

Mc-Val-Cit-PABC-PNP is a peptide linker molecule used in the synthesis of antibody-drug conjugates (ADCs). It contains a maleimidocaproyl (Mc) group that can be conjugated to an antibody and a p-nitrophenol (PNP) group that allows the peptide to be linked to anticancer compounds, such as doxorubicin or monomethyl auristatin E (MMAE; ). ADCs target specific cell populations to induce a selective response, such as cell death in cancer cells.

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