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ChemicalBook >> CAS DataBase List >> Losartan potassium

Losartan potassium

Losartan potassium price.
  • $5 - $541
  • Product name: Losartan potassium
  • CAS: 124750-99-8
  • MF: C22H23ClKN6O
  • MW: 462.01
  • EINECS:200-287-4
  • MDL Number:MFCD02092704
  • Synonyms:2-BUTYL-4-CHLORO-1-[[2'-(1H-TETRAZOL-5YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1H-IMIDAZOLE-5-METHANOL;2-butyl-4-chloro-1-[[2'-(1h-tetrazol-5-yl)[1,1'-biphenyl]-4-yl]methyl]-1h-imidazole-5-methanol monopotassium salt;2-BUTYL-4-CHLORO-1-[[2'-(1H-TETRAZOLE-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1H-IMIDAZOLE-5-METHANOL, POTASSIUM SALT;LOSARTAN MONOPOTASSIUM SALT;LOSARTAN POTASSIUM;MK 954;1h-imidazole-5-methanol,2-butyl-4-chloro-1-((2’-(1h-tetrazol-5-yl)(1,1’-biphe ;2-butyl-4-chloro-1-(2’-(tetrazol-5-yl)biphenyl-4-ylmethyl)-1h-imidazole-5-me
47 prices
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Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • AstaTech
  • AvaChem
  • Biorbyt Ltd
  • Biosynth Carbosynth
  • Cayman Chemical
  • Chem-Impex
  • ChemScene
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Matrix Scientific
  • Sigma-Aldrich
  • TCI Chemical
  • Tocris
  • TRC
  • Usbiological
Package
  • 50mg
  • y0001062
  • 10mg
  • 150mg
  • 0.500g
  • 500mg
  • 5/ G
  • 100mg
  • 1g
  • 5g
  • 100g
  • 10g
  • 25g
  • 50
  • 10mM(in 1mL DMSO)
  • 25/ G
  • 100/ G
  • ManufacturerAK Scientific
  • Product numberJ10063
  • Product descriptionLosartan Potassium
  • Packaging100mg
  • Price$148
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA561984
  • Product description(1-((2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methanol,potassiumsalt 98+%
  • Packaging1g
  • Price$5
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA561984
  • Product description(1-((2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methanol,potassiumsalt 98+%
  • Packaging5g
  • Price$7
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA561984
  • Product description(1-((2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methanol,potassiumsalt 98+%
  • Packaging10g
  • Price$13
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA561984
  • Product description(1-((2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methanol,potassiumsalt 98+%
  • Packaging25g
  • Price$16
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA561984
  • Product description(1-((2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methanol,potassiumsalt 98+%
  • Packaging100g
  • Price$63
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003216
  • Product descriptionLOSARTAN POTASSIUM 95.00%
  • Packaging100MG
  • Price$407.9
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003216
  • Product descriptionLOSARTAN POTASSIUM 95.00%
  • Packaging1G
  • Price$479
  • Updated2021-12-16
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  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0003216
  • Product descriptionLOSARTAN POTASSIUM 95.00%
  • Packaging5G
  • Price$541
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1425
  • Product descriptionLosartanPotassium(DuP753)
  • Packaging1g
  • Price$48
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1425
  • Product descriptionLosartanPotassium(DuP753)
  • Packaging10mM(in 1mL DMSO)
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA1425
  • Product descriptionLosartanPotassium(DuP753)
  • Packaging5g
  • Price$114
  • Updated2021-12-16
  • Buy
  • ManufacturerAstaTech
  • Product number40296
  • Product description2-BUTYL-4-CHLORO-1-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1H-IMIDAZOLE-5-METHANOLMONOPOTASSIUMSALT 97%
  • Packaging5/ G
  • Price$53
  • Updated2021-12-16
  • Buy
  • ManufacturerAstaTech
  • Product number40296
  • Product description2-BUTYL-4-CHLORO-1-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1H-IMIDAZOLE-5-METHANOLMONOPOTASSIUMSALT 97%
  • Packaging25/ G
  • Price$160
  • Updated2021-12-16
  • Buy
  • ManufacturerAstaTech
  • Product number40296
  • Product description2-BUTYL-4-CHLORO-1-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1H-IMIDAZOLE-5-METHANOLMONOPOTASSIUMSALT 97%
  • Packaging100/ G
  • Price$399
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number1645
  • Product descriptionLosartan Potassium
  • Packaging100mg
  • Price$35
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J10063 Losartan Potassium 100mg $148 2021-12-16 Buy
Ambeed A561984 (1-((2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methanol,potassiumsalt 98+% 1g $5 2021-12-16 Buy
Ambeed A561984 (1-((2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methanol,potassiumsalt 98+% 5g $7 2021-12-16 Buy
Ambeed A561984 (1-((2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methanol,potassiumsalt 98+% 10g $13 2021-12-16 Buy
Ambeed A561984 (1-((2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methanol,potassiumsalt 98+% 25g $16 2021-12-16 Buy
Ambeed A561984 (1-((2'-(2H-Tetrazol-5-yl)-[1,1'-biphenyl]-4-yl)methyl)-2-butyl-4-chloro-1H-imidazol-5-yl)methanol,potassiumsalt 98+% 100g $63 2021-12-16 Buy
American Custom Chemicals Corporation API0003216 LOSARTAN POTASSIUM 95.00% 100MG $407.9 2021-12-16 Buy
American Custom Chemicals Corporation API0003216 LOSARTAN POTASSIUM 95.00% 1G $479 2021-12-16 Buy
American Custom Chemicals Corporation API0003216 LOSARTAN POTASSIUM 95.00% 5G $541 2021-12-16 Buy
ApexBio Technology A1425 LosartanPotassium(DuP753) 1g $48 2021-12-16 Buy
ApexBio Technology A1425 LosartanPotassium(DuP753) 10mM(in 1mL DMSO) $55 2021-12-16 Buy
ApexBio Technology A1425 LosartanPotassium(DuP753) 5g $114 2021-12-16 Buy
AstaTech 40296 2-BUTYL-4-CHLORO-1-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1H-IMIDAZOLE-5-METHANOLMONOPOTASSIUMSALT 97% 5/ G $53 2021-12-16 Buy
AstaTech 40296 2-BUTYL-4-CHLORO-1-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1H-IMIDAZOLE-5-METHANOLMONOPOTASSIUMSALT 97% 25/ G $160 2021-12-16 Buy
AstaTech 40296 2-BUTYL-4-CHLORO-1-[[2'-(1H-TETRAZOL-5-YL)[1,1'-BIPHENYL]-4-YL]METHYL]-1H-IMIDAZOLE-5-METHANOLMONOPOTASSIUMSALT 97% 100/ G $399 2021-12-16 Buy
AvaChem 1645 Losartan Potassium 100mg $35 2021-12-16 Buy

Properties

Melting point :263-265°C
storage temp. :Inert atmosphere,Room Temperature
solubility :Freely soluble in water and in methanol, slightly soluble in acetonitrile.
form :powder or crystals
color :Off-white
Merck :14,5583
BRN :5845770
BCS Class :1
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 2 months.
InChI :InChI=1S/C22H22ClN6O.K/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22;/h4-7,9-12,30H,2-3,8,13-14H2,1H3;/q-1;+1
InChIKey :OXCMYAYHXIHQOA-UHFFFAOYSA-N
SMILES :C1(C=CC=CC=1C1=CC=C(CN2C(CO)=C(Cl)N=C2CCCC)C=C1)C1=NN=NN1[K]
CAS DataBase Reference :124750-99-8(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P312 Call a POISON CENTER or doctor/physician if you feel unwell.
P403+P233 Store in a well-ventilated place. Keep container tightly closed.

Description

As a angiotensin II receptor antagonist, Losartan Potassium is the potassium salt of losartan with antihypertensive activity, which is mainly used in the therapy of high blood pressure (hypertension) and diabetic nephropathy. It functions by relaxing blood vessels so that blood can flow more easily. It is also effective to help protect the kidneys from damage caused by diabetes and lower the risks of stroke in patients suffering from hypertension and myocardial enlargement. Besides, recent study has suggested that losartan is beneficial to reverse age related dysfunction in maintaining normal blood pressure and cellular energy usage on mitochondria and it can probably be used to treat left ventricular hypertrophy. It may also be used as an alternative agent for the treatment of systolic dysfunction, myocardial infarction, coronary artery disease, and heart failure.

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