Loratadine
- $10 - $2887.5
- Product name: Loratadine
- CAS: 79794-75-5
- MF: C22H23ClN2O2
- MW: 382.88
- EINECS:935-907-9
- MDL Number:MFCD00672869
- Synonyms:LORATADINE;LORATADINE-D5;4-(8-Chloro-10,11-dihydro-4-aza-5H-dibenzo[a,d]cycloheptene-5-ylidene)piperidine-1-carboxylic acid ethyl ester;4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridine-11-ylidene)piperidine-1-carboxylic acid ethyl ester;Loratadine,4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene-1-piperidinecarboxylic acid ethyl ester, Loratidine;anium wilfordii Maxim;4(8-CHLORO-5,6-DIHYDRO-11H-BENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDIN-11-YLIDENE)-1-PIPERIDINECARBOXYLATE;4-(8-CHLORO-5,6-DIHYDRO-11H-BENZO[5,6]CYCLOHEPTA[1,2-B]PYRIDIN-11-YLIDENE)-1-PIPERIDINECARBOXYLIC ACID ETHYL ESTER
45 prices
Selected condition:
Brand
- AHH
- AK Scientific
- Alfa Aesar
- American Custom Chemicals Corporation
- ApexBio Technology
- AvaChem
- Biosynth Carbosynth
- Cayman Chemical
- Chem-Impex
- Crysdot
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- TCI Chemical
- Tocris
- TRC
- Usbiological
Package
- 1MG
- 10MG
- 5mg
- 10
- y0000603
- 25mg
- 50mg
- 100MG
- 200mg
- 50
- 250mg
- 500mg
- 1g
- 5g
- 10g
- 25g
- 100g
- 500g
- y0000688
- ManufacturerAHH
- Product numberAPI-1744
- Product descriptionLoratadine 98%
- Packaging25g
- Price$400
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberJ95747
- Product descriptionLoratadine
- Packaging1g
- Price$10
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberG291
- Product descriptionLoratadine
- Packaging5g
- Price$25
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product numberG291
- Product descriptionLoratadine
- Packaging500g
- Price$534
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ60190
- Product descriptionLoratadine, 98+%
- Packaging500mg
- Price$90.65
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberJ60190
- Product descriptionLoratadine, 98+%
- Packaging1g
- Price$150.65
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberJ60190
- Product descriptionLoratadine, 98+%
- Packaging5g
- Price$561.65
- Updated2024-03-01
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0003212
- Product descriptionLORATADINE 95.00%
- Packaging100MG
- Price$401.98
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0003212
- Product descriptionLORATADINE 95.00%
- Packaging1G
- Price$419.8
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberRDL0006911
- Product descriptionLORATADINE-D5 95.00%
- Packaging1MG
- Price$866.25
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberRDL0006911
- Product descriptionLORATADINE-D5 95.00%
- Packaging10MG
- Price$2887.5
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA2960
- Product descriptionLoratadine
- Packaging5mg
- Price$40
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA2960
- Product descriptionLoratadine
- Packaging100mg
- Price$190
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2987
- Product descriptionLoratadine
- Packaging250mg
- Price$39
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2987
- Product descriptionLoratadine
- Packaging1g
- Price$59
- Updated2021-12-16
- Buy
- ManufacturerAvaChem
- Product number2987
- Product descriptionLoratadine
- Packaging10g
- Price$290
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AHH | API-1744 | Loratadine 98% | 25g | $400 | 2021-12-16 | Buy |
AK Scientific | J95747 | Loratadine | 1g | $10 | 2021-12-16 | Buy |
AK Scientific | G291 | Loratadine | 5g | $25 | 2021-12-16 | Buy |
AK Scientific | G291 | Loratadine | 500g | $534 | 2021-12-16 | Buy |
Alfa Aesar | J60190 | Loratadine, 98+% | 500mg | $90.65 | 2024-03-01 | Buy |
Alfa Aesar | J60190 | Loratadine, 98+% | 1g | $150.65 | 2024-03-01 | Buy |
Alfa Aesar | J60190 | Loratadine, 98+% | 5g | $561.65 | 2024-03-01 | Buy |
American Custom Chemicals Corporation | API0003212 | LORATADINE 95.00% | 100MG | $401.98 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0003212 | LORATADINE 95.00% | 1G | $419.8 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | RDL0006911 | LORATADINE-D5 95.00% | 1MG | $866.25 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | RDL0006911 | LORATADINE-D5 95.00% | 10MG | $2887.5 | 2021-12-16 | Buy |
ApexBio Technology | A2960 | Loratadine | 5mg | $40 | 2021-12-16 | Buy |
ApexBio Technology | A2960 | Loratadine | 100mg | $190 | 2021-12-16 | Buy |
AvaChem | 2987 | Loratadine | 250mg | $39 | 2021-12-16 | Buy |
AvaChem | 2987 | Loratadine | 1g | $59 | 2021-12-16 | Buy |
AvaChem | 2987 | Loratadine | 10g | $290 | 2021-12-16 | Buy |
Properties
Melting point :134-136°C
Boiling point :531.3±50.0 °C(Predicted)
Density :1.261±0.06 g/cm3(Predicted)
RTECS :TM6129200
storage temp. :2-8°C
solubility :DMSO: 26 mg/mL, soluble
form :powder
pka :4.27±0.20(Predicted)
color :white
Water Solubility :It is soluble in DMSO (50 mg/ml), ethanol (77 mg/ml at 25°C), water (<1 mg/ml at 25°C), chloroform, and methanol.
Merck :14,5578
BCS Class :2
Stability :Stable, but may be heat sensitive - refrigerate. Incompatible with strong oxidizing agents.
InChIKey :JCCNYMKQOSZNPW-UHFFFAOYSA-N
CAS DataBase Reference :79794-75-5(CAS DataBase Reference)
EPA Substance Registry System :1-Piperidinecarboxylic acid, 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-, ethyl ester (79794-75-5)
Boiling point :531.3±50.0 °C(Predicted)
Density :1.261±0.06 g/cm3(Predicted)
RTECS :TM6129200
storage temp. :2-8°C
solubility :DMSO: 26 mg/mL, soluble
form :powder
pka :4.27±0.20(Predicted)
color :white
Water Solubility :It is soluble in DMSO (50 mg/ml), ethanol (77 mg/ml at 25°C), water (<1 mg/ml at 25°C), chloroform, and methanol.
Merck :14,5578
BCS Class :2
Stability :Stable, but may be heat sensitive - refrigerate. Incompatible with strong oxidizing agents.
InChIKey :JCCNYMKQOSZNPW-UHFFFAOYSA-N
CAS DataBase Reference :79794-75-5(CAS DataBase Reference)
EPA Substance Registry System :1-Piperidinecarboxylic acid, 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-, ethyl ester (79794-75-5)
Safety Information
Symbol(GHS): | |||||||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Signal word: | Warning | ||||||||||||||||||||||||||||
Hazard statements: |
|
||||||||||||||||||||||||||||
Precautionary statements: |
|
Description
Loratadine is a non-sedating antihistamine that acts as a selective inverse agonist of peripheral histamine H1 receptors (Ki = 35 nM). It has been shown to inhibit the release of leukotriene C4 (IC50 = 8 μM) and histamine (IC50 = 11 μM) from rodent mast cells and to inhibit allergic bronchospasm in guinea pigs with an ED50 value of 0.40 mg/kg.More related product prices
Epichlorohydrin Etanol 2,6-Dimethyl-7-octen-2-ol Haloperidol Ethyl acetate 98437-23-1 Tetraheptylammonium bromide Ethylparaben Chromium picolinate 2,5-PYRIDINEDICARBOXYLIC ACID Ebastine 38092-89-6 Loratadine EP IMpurity F 31251-41-9 2,8-Dichloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-β]pyridin-11-one 4-[[3-[2-(3-Chlorophenyl)ethyl]-2-pyridinyl]carbonyl]-1-piperidinecarboxylic AcidRelated product price
- Epichlorohydrin
$9-12000 - Etanol
$10-17310 - 2,6-Dimethyl-7-octen-2-ol
$45-1834.57
Suppliers and manufacturers
APOLLO HEALTHCARE RESOURCES
Shenzhen Monkono Technology Co.,Ltd
Chengdu Aupone Pharmaceutical Co.Ltd.
Shandong Hanjiang Chemical Co., Ltd