天堂网亚洲,天天操天天搞,91视频高清,菠萝蜜视频在线观看入口,美女视频性感美女视频,95丝袜美女视频国产,超高清美女视频图片

Welcome to chemicalbook!
400-158-6606
Inquriy
Try our best to find the right business for you.
Do not miss inquiry messages Please log in to view all inquiry messages.

Welcome back!

ChemicalBook >> CAS DataBase List >> GAMBOGIC ACID

GAMBOGIC ACID

GAMBOGIC ACID price.
  • $33 - $4151
  • Product name: GAMBOGIC ACID
  • CAS: 2752-65-0
  • MF: C38H44O8
  • MW: 628.75
  • EINECS:
  • MDL Number:MFCD16878985
  • Synonyms:GaMbogic aci;BETA-GUTTIFERIN;BETA-GUTTILACTONE;GAMBOGIC ACID;GUTTATIC ACID;β-Guttilactone;2-Butenoic acid, 2-methyl-4-[(1R,3aS,5S,11R,14aS)-3a,4,5,7-tetrahydro-8-hydroxy-3,3,11-trimethyl-13-(3-methyl-2-buten-1-yl)-11-(4-methyl-3-penten-1-yl)-7,15-dioxo-1,5-methano-1H,3H,11H-furo[3,4-g]pyrano[3,2-b]xanthen-1-yl]-, (2Z)-;1,5-Methano-1H,3H,11H-furo(3,4-g)pyrano(3,2-b)xanthene-1-crotonic acid
39 prices
Selected condition：
Brand
  • AK Scientific
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Arctom
  • AvaChem
  • Biorbyt Ltd
  • BroadPharm
  • Cayman Chemical
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 1mg
  • 5mg
  • 10MG
  • 20mg
  • 25mg
  • 10
  • 50
  • 100mg
  • 250mg
  • 10mM(in 1mL DMSO)
  • 50mg
  • 1g
  • ManufacturerAK Scientific
  • Product numberX1145
  • Product descriptionGambogic acid
  • Packaging50mg
  • Price$375
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberX1145
  • Product descriptionGambogic acid
  • Packaging100mg
  • Price$742
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA200522
  • Product descriptionGambogic acid ≥97%(HPLC)
  • Packaging50mg
  • Price$82
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA200522
  • Product descriptionGambogic acid ≥97%(HPLC)
  • Packaging100mg
  • Price$125
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA200522
  • Product descriptionGambogic acid ≥97%(HPLC)
  • Packaging250mg
  • Price$189
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberPXT0004738
  • Product descriptionGAMBOGIC ACID 95.00%
  • Packaging10MG
  • Price$648.83
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA3424
  • Product descriptionGambogic acid
  • Packaging10mM(in 1mL DMSO)
  • Price$90
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN90172
  • Product descriptionGambogic acid ≥98%
  • Packaging20mg
  • Price$118
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberSY074643
  • Product descriptionGambogic acid ≥95%
  • Packaging10mg
  • Price$182.73
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberAS054326
  • Product descriptionGambogic acid ≥98%
  • Packaging100mg
  • Price$364
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2366
  • Product descriptionGambogic acid
  • Packaging5mg
  • Price$45
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2366
  • Product descriptionGambogic acid
  • Packaging25mg
  • Price$145
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2366
  • Product descriptionGambogic acid
  • Packaging100mg
  • Price$385
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2366
  • Product descriptionGambogic acid
  • Packaging250mg
  • Price$685
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2366
  • Product descriptionGambogic acid
  • Packaging1g
  • Price$1485
  • Updated2021-12-16
  • Buy
  • ManufacturerBiorbyt Ltd
  • Product numberorb546016
  • Product descriptionGambogic acid >98%
  • Packaging5mg
  • Price$173.4
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific X1145 Gambogic acid 50mg $375 2021-12-16 Buy
AK Scientific X1145 Gambogic acid 100mg $742 2021-12-16 Buy
Ambeed A200522 Gambogic acid ≥97%(HPLC) 50mg $82 2021-12-16 Buy
Ambeed A200522 Gambogic acid ≥97%(HPLC) 100mg $125 2021-12-16 Buy
Ambeed A200522 Gambogic acid ≥97%(HPLC) 250mg $189 2021-12-16 Buy
American Custom Chemicals Corporation PXT0004738 GAMBOGIC ACID 95.00% 10MG $648.83 2021-12-16 Buy
ApexBio Technology A3424 Gambogic acid 10mM(in 1mL DMSO) $90 2021-12-16 Buy
Arctom CFN90172 Gambogic acid ≥98% 20mg $118 2021-12-16 Buy
Arctom SY074643 Gambogic acid ≥95% 10mg $182.73 2021-12-16 Buy
Arctom AS054326 Gambogic acid ≥98% 100mg $364 2021-12-16 Buy
AvaChem 2366 Gambogic acid 5mg $45 2021-12-16 Buy
AvaChem 2366 Gambogic acid 25mg $145 2021-12-16 Buy
AvaChem 2366 Gambogic acid 100mg $385 2021-12-16 Buy
AvaChem 2366 Gambogic acid 250mg $685 2021-12-16 Buy
AvaChem 2366 Gambogic acid 1g $1485 2021-12-16 Buy
Biorbyt Ltd orb546016 Gambogic acid >98% 5mg $173.4 2021-12-16 Buy

Properties

Melting point :88.5°C
Boiling point :586.06°C (rough estimate)
alpha :D20 -685° (methanol)
Density :1.1057 (rough estimate)
refractive index :1.5290 (estimate)
storage temp. :-20°C
solubility :DMSO: ≥10mg/mL
form :powder
pka :4.58±0.36(Predicted)
color :yellow to orange
Stability :Stable for 1 year as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
InChIKey :GEZHEQNLKAOMCA-XKZIYDEJSA-N
LogP :6.490 (est)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Gambogic acid (GA) is a natural product isolated from the G. hanburyi tree that exhibits anti-cancer activity by acting on a variety of cellular pathways. In the apoptotic pathway, GA activates caspases (EC50 = 0.78 μM), inhibits binding of anti-apoptotic proteins to a BH3 peptide (IC50 = 1.47, 1.21, 2.02, 0.66, 1.06, 0.79 μM for Bcl-xL, Bcl-2, Bcl-W, Bcl-B, Bfl-1, Mcl-1, respectively), and alters expression of Bcl-2 and Bax. GA binds to the transferrin receptor (IC50 = 4.1 μM), inducing apoptosis in various tumor cell lines. It is a potent, slow inhibitor of Kir2.1 channels (IC50 = <100 nM). GA inhibits the chymotrypsin activity of the 20S proteasome in a dose-dependent manner. A novel mechanism for GA cytotoxic effects in glioma cells may be through AMPK-initiated effects on EGFR and Akt/mTORC1 signaling.

More related product prices

6-METHYL-4-CHROMANONE

Related product price