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ChemicalBook >> CAS DataBase List >> FASUDIL

FASUDIL

FASUDIL price.
  • $49 - $923
  • Product name: FASUDIL
  • CAS: 103745-39-7
  • MF: C14H17N3O2S
  • MW: 291.37
  • EINECS:816-154-4
  • MDL Number:MFCD00153805
  • Synonyms:Fasudil Hydrochloride Injection;1-(5-ISOQUINOLINE-SULFONYL)-HOMOPIPERAZINE;at877 ;hexahydro-1-(5-isoquinolinylsulfonyl)-1h-4-diazepine ;HA-1077 DIHYDROCHLORIDE NOVEL VASODILATO R AGE;HA 1077, DIHYDROCHLORIDE, 99+%;FASUDIL;Hexahydro-1-(5-isoquinolinylsulfonyl)-1H-1,4-diazepine
12 prices
Selected condition：
Brand
  • Alfa Aesar
  • ApexBio Technology
  • AvaChem
  • Crysdot
  • CSNpharm
  • DC Chemicals
  • Labseeker
  • Sigma-Aldrich
  • TRC
Package
  • 1mg
  • 10mg
  • 100mg
  • 200mg
  • 250mg
  • 500mg
  • 1g
  • 10g
  • 100g
  • ManufacturerAlfa Aesar
  • Product numberJ63525
  • Product descriptionFasudil, 98+%
  • Packaging10mg
  • Price$243.65
  • Updated2024-03-01
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB3523
  • Product descriptionFasudil
  • Packaging200mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB3523
  • Product descriptionFasudil
  • Packaging500mg
  • Price$120
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2787B
  • Product descriptionFasudil
  • Packaging100mg
  • Price$49
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2787B
  • Product descriptionFasudil
  • Packaging1g
  • Price$109
  • Updated2021-12-16
  • Buy
  • ManufacturerAvaChem
  • Product number2787B
  • Product descriptionFasudil
  • Packaging10g
  • Price$590
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31004760
  • Product descriptionFasudil 98+%
  • Packaging250mg
  • Price$63
  • Updated2021-12-16
  • Buy
  • ManufacturerCSNpharm
  • Product numberCSN10983
  • Product descriptionFasudil
  • Packaging250mg
  • Price$67
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC36791
  • Product descriptionFasudil
  • Packaging1g
  • Price$350
  • Updated2021-12-16
  • Buy
  • ManufacturerLabseeker
  • Product numberSC-22700
  • Product description(5-ISOQUINOLINESULFONYL)HOMOPIPERAZINE,2HCL 95
  • Packaging100g
  • Price$923
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product number371970
  • Product descriptionHA 1077, Dihydrochloride - CAS 103745-39-7 - Calbiochem
  • Packaging1mg
  • Price$159
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberF150023
  • Product descriptionFasudil
  • Packaging100mg
  • Price$165
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Alfa Aesar J63525 Fasudil, 98+% 10mg $243.65 2024-03-01 Buy
ApexBio Technology B3523 Fasudil 200mg $70 2021-12-16 Buy
ApexBio Technology B3523 Fasudil 500mg $120 2021-12-16 Buy
AvaChem 2787B Fasudil 100mg $49 2021-12-16 Buy
AvaChem 2787B Fasudil 1g $109 2021-12-16 Buy
AvaChem 2787B Fasudil 10g $590 2021-12-16 Buy
Crysdot CD31004760 Fasudil 98+% 250mg $63 2021-12-16 Buy
CSNpharm CSN10983 Fasudil 250mg $67 2021-12-16 Buy
DC Chemicals DC36791 Fasudil 1g $350 2021-12-16 Buy
Labseeker SC-22700 (5-ISOQUINOLINESULFONYL)HOMOPIPERAZINE,2HCL 95 100g $923 2021-12-16 Buy
Sigma-Aldrich 371970 HA 1077, Dihydrochloride - CAS 103745-39-7 - Calbiochem 1mg $159 2024-03-01 Buy
TRC F150023 Fasudil 100mg $165 2021-12-16 Buy

Properties

Boiling point :506.2±60.0 °C(Predicted)
Density :1.289±0.06 g/cm3(Predicted)
storage temp. :Store at RT
solubility :H2O: >200 mg/mL
form :solid
pka :9.73±0.20(Predicted)
color :white
Water Solubility :Soluble in water or DMSO
CAS DataBase Reference :103745-39-7(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

HA-1077 dihydrochloride has been shown to be a vasodilating agent as well as a potent inhibitor of Rock-2 (Rho-associated Kinase II), cGKI (cGMP-dependent protein kinase), PKA (cAMP-dependent protein kinase), MYLK, and CaMKII. Rho kinase signaling pathways are thought to cause invasion, migration, and proliferation of certain cells. Studies have shown this compound can also inhibit myosin light chain kinase in vitro and suppress cell rounding by myosin light chain phosphorylation. Mechanistic experiments report that HA-1077 inhibits vascular smooth muscle contraction by acting as a calcium channel protein inhibitor. HA-1077 dihydrochloride is an inhibitor of MSK1, PKC, PRK2 and Rsk-2.

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