Ertapenem Disodium
- $32 - $1233
- Product name: Ertapenem Disodium
- CAS: 153832-38-3
- MF: C22H26N3NaO7S
- MW: 499.51
- EINECS:
- MDL Number:MFCD00922233
- Synonyms:1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid;ErtapeneM SodiuM(crude);disodium (4R,5R,6S)-3-[(3S,5S)-5-[(3-carboxylatophenyl)carbamoyl]pyrro lidin-3-yl]sulfanyl-6-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2 .0]hept-2-ene-2-carboxylate;Ertapenem disodium;Ertapenem Disodium (85%);Ertapenem (sodium salt);Ertapenam disodium;Ertapenem Disodium 90%
16 prices
Selected condition:
Brand
- AccelPharmtech
- American Custom Chemicals Corporation
- ApexBio Technology
- Biorbyt Ltd
- Cayman Chemical
- Chemenu
- Crysdot
- Labseeker
- TRC
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 100MG
- 250mg
- 950MG
- 1g
- 25g
- ManufacturerAccelPharmtech
- Product numberAT7169
- Product descriptionErtapenemDisodium 98.00%
- Packaging950MG
- Price$120
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberAPI0019498
- Product descriptionERTAPENEM DISODIUM 95.00%
- Packaging100MG
- Price$407.4
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3451
- Product descriptionErtapenem(sodiumsalt)
- Packaging5mg
- Price$95
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3451
- Product descriptionErtapenem(sodiumsalt)
- Packaging10mg
- Price$163
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberC3451
- Product descriptionErtapenem(sodiumsalt)
- Packaging25mg
- Price$339
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb134781
- Product descriptionErtapenem Sodium >99%
- Packaging100mg
- Price$414.8
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb134781
- Product descriptionErtapenem Sodium >99%
- Packaging250mg
- Price$615.4
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb134781
- Product descriptionErtapenem Sodium >99%
- Packaging1g
- Price$1208.7
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number20523
- Product descriptionErtapenem (sodium salt) ≥98%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number20523
- Product descriptionErtapenem (sodium salt) ≥98%
- Packaging5mg
- Price$109
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number20523
- Product descriptionErtapenem (sodium salt) ≥98%
- Packaging10mg
- Price$184
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number20523
- Product descriptionErtapenem (sodium salt) ≥98%
- Packaging25mg
- Price$381
- Updated2024-03-01
- Buy
- ManufacturerChemenu
- Product numberCM197849
- Product descriptionErtapenemdisodium 98%
- Packaging1g
- Price$669
- Updated2021-12-16
- Buy
- ManufacturerCrysdot
- Product numberCD11248687
- Product descriptionErtapenemdisodium 85%
- Packaging1g
- Price$715
- Updated2021-12-16
- Buy
- ManufacturerLabseeker
- Product numberSC-20517
- Product descriptionErtapenemsodium 97
- Packaging25g
- Price$1233
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberE635000
- Product descriptionErtapenemDisodium90%
- Packaging100mg
- Price$820
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AccelPharmtech | AT7169 | ErtapenemDisodium 98.00% | 950MG | $120 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | API0019498 | ERTAPENEM DISODIUM 95.00% | 100MG | $407.4 | 2021-12-16 | Buy |
ApexBio Technology | C3451 | Ertapenem(sodiumsalt) | 5mg | $95 | 2021-12-16 | Buy |
ApexBio Technology | C3451 | Ertapenem(sodiumsalt) | 10mg | $163 | 2021-12-16 | Buy |
ApexBio Technology | C3451 | Ertapenem(sodiumsalt) | 25mg | $339 | 2021-12-16 | Buy |
Biorbyt Ltd | orb134781 | Ertapenem Sodium >99% | 100mg | $414.8 | 2021-12-16 | Buy |
Biorbyt Ltd | orb134781 | Ertapenem Sodium >99% | 250mg | $615.4 | 2021-12-16 | Buy |
Biorbyt Ltd | orb134781 | Ertapenem Sodium >99% | 1g | $1208.7 | 2021-12-16 | Buy |
Cayman Chemical | 20523 | Ertapenem (sodium salt) ≥98% | 1mg | $32 | 2024-03-01 | Buy |
Cayman Chemical | 20523 | Ertapenem (sodium salt) ≥98% | 5mg | $109 | 2024-03-01 | Buy |
Cayman Chemical | 20523 | Ertapenem (sodium salt) ≥98% | 10mg | $184 | 2024-03-01 | Buy |
Cayman Chemical | 20523 | Ertapenem (sodium salt) ≥98% | 25mg | $381 | 2024-03-01 | Buy |
Chemenu | CM197849 | Ertapenemdisodium 98% | 1g | $669 | 2021-12-16 | Buy |
Crysdot | CD11248687 | Ertapenemdisodium 85% | 1g | $715 | 2021-12-16 | Buy |
Labseeker | SC-20517 | Ertapenemsodium 97 | 25g | $1233 | 2021-12-16 | Buy |
TRC | E635000 | ErtapenemDisodium90% | 100mg | $820 | 2021-12-16 | Buy |
Properties
Melting point :230-234°C (dec.)
storage temp. :Sealed in dry,2-8°C
solubility :Methanol (Slightly), Water (Slightly)
form :Solid
color :White to Off-White
Stability :Unstable at room temperature!
storage temp. :Sealed in dry,2-8°C
solubility :Methanol (Slightly), Water (Slightly)
form :Solid
color :White to Off-White
Stability :Unstable at room temperature!
Safety Information
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Signal word: | Warning | |||||||||||||||||||||
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Description
Ertapenem sodium was introduced in the US as a once daily intravenous or intramuscular injection for the treatment of adult patients with moderate to severe bacterial infections. This new I-β-methyl carbapenem can be assembled from commercially available 4-nitrobenzyl protected β-methyl carbapenem enolphosphate and the appropriate thiol derivative. The last intermediate can be synthesized from a suitably N-protected 4- hydroxy proline derivative in a one pot operation involving bis activation of the carboxy and hydroxy groups, reaction with sodium sulfide yielding the corresponding thiolactone, aminolysis with 2-aminobenzoic acid and Kdeprotection. This bacterial cell wall synthesis inhibitor has broad spectrum antimicrobial activity including common Gram-positive and Gram-negative aerobic pathogens and restricted activity against nosocomial pathogens such as Pseudomonas aeruginosa, Acinetobacfer species, methicillin-resistant staphylococci and enterococci. Ertapenem is resistant to a broad and extended spectrum of β-lactamases (excluding metallo-beta-lactamase) and is also more resistant than imipenem to human renal dehydroxypeptidase-I-inactivation (DHP-I). In drug-resistant strains of P. aeruginosa, resistance to ertapenem and imipenem was common but almost all strains remain susceptible to at least one antipseudomal agent. In phase III studies, ertapenem showed efficacy in the treatment of obstetric and gyneacological infections, skin and soft tissues infections, community-acquired pneumonia, urinary tract infections and in intra abdominal infections. Ertapenem has improved pharmacokinetics over currently available carbapenems and cephalosporins with an extended serum half-life of 4h. The overall safety and tolerability profile of ertapenem was comparable to that seen with comparator antibacterials.Related product price
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