EMBELIN
- $57 - $2176
- Product name: EMBELIN
- CAS: 550-24-3
- MF: C17H26O4
- MW: 294.39
- EINECS:208-979-8
- MDL Number:MFCD00016369
- Synonyms:2,5-dihydroxy-3-undecyl-p-benzoquinon ;4-dione,2,5-dihydroxy-3-undecyl-5-cyclohexadiene-1 ;embelicacid ;emberine ;APOPTOSIS ACTIVATOR III;EMBELIN;2,5-DIHYDROXY-3-UNDECYL-1,4-BENZOQUINONE;2,5-DIHYDROXY-3-UNDECYL-2,5-CYCLOHEXADIENE-1,4-DIONE
42 prices
Selected condition:
Brand
- AK Scientific
- Alfa Aesar
- Ambeed
- American Custom Chemicals Corporation
- ApexBio Technology
- Arctom
- Biorbyt Ltd
- Biosynth Carbosynth
- BroadPharm
- Cayman Chemical
- ChemScene
- CSNpharm
- DC Chemicals
- Matrix Scientific
- Medical Isotopes, Inc.
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 20mg
- 10
- 10mg
- 25mg
- 50mg
- 100mg
- 250mg
- 50
- 1g
- 5G
- ManufacturerAK Scientific
- Product numberV0365
- Product descriptionEmbelin
- Packaging10mg
- Price$64
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ64074
- Product descriptionEmbelin
- Packaging10mg
- Price$91.65
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberJ64074
- Product descriptionEmbelin
- Packaging50mg
- Price$303.65
- Updated2024-03-01
- Buy
- ManufacturerAmbeed
- Product numberA116360
- Product descriptionEmbelin 98+%
- Packaging10mg
- Price$60
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA116360
- Product descriptionEmbelin 98+%
- Packaging25mg
- Price$94
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA116360
- Product descriptionEmbelin 98+%
- Packaging50mg
- Price$160
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA116360
- Product descriptionEmbelin 98+%
- Packaging100mg
- Price$256
- Updated2021-12-16
- Buy
- ManufacturerAmbeed
- Product numberA116360
- Product descriptionEmbelin 98+%
- Packaging1g
- Price$2176
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCHM0019661
- Product descriptionEMBELIN 95.00%
- Packaging5G
- Price$902.29
- Updated2021-12-16
- Buy
- ManufacturerAmerican Custom Chemicals Corporation
- Product numberCHM0019661
- Product descriptionEMBELIN 95.00%
- Packaging1G
- Price$636.7
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberA8235
- Product descriptionEmbelin
- Packaging50mg
- Price$190
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS016713
- Product descriptionEmbelin ≥98%
- Packaging10mg
- Price$59
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberCFN90537
- Product descriptionEmbelin ≥98%
- Packaging20mg
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS016713
- Product descriptionEmbelin ≥98%
- Packaging25mg
- Price$93
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberAS016713
- Product descriptionEmbelin ≥98%
- Packaging50mg
- Price$158
- Updated2021-12-16
- Buy
- ManufacturerArctom
- Product numberSY064447
- Product description2,5-Dihydroxy-3-undecyl-[1,4]benzoquinone
- Packaging10mg
- Price$158.18
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | V0365 | Embelin | 10mg | $64 | 2021-12-16 | Buy |
Alfa Aesar | J64074 | Embelin | 10mg | $91.65 | 2024-03-01 | Buy |
Alfa Aesar | J64074 | Embelin | 50mg | $303.65 | 2024-03-01 | Buy |
Ambeed | A116360 | Embelin 98+% | 10mg | $60 | 2021-12-16 | Buy |
Ambeed | A116360 | Embelin 98+% | 25mg | $94 | 2021-12-16 | Buy |
Ambeed | A116360 | Embelin 98+% | 50mg | $160 | 2021-12-16 | Buy |
Ambeed | A116360 | Embelin 98+% | 100mg | $256 | 2021-12-16 | Buy |
Ambeed | A116360 | Embelin 98+% | 1g | $2176 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | CHM0019661 | EMBELIN 95.00% | 5G | $902.29 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | CHM0019661 | EMBELIN 95.00% | 1G | $636.7 | 2021-12-16 | Buy |
ApexBio Technology | A8235 | Embelin | 50mg | $190 | 2021-12-16 | Buy |
Arctom | AS016713 | Embelin ≥98% | 10mg | $59 | 2021-12-16 | Buy |
Arctom | CFN90537 | Embelin ≥98% | 20mg | $80 | 2021-12-16 | Buy |
Arctom | AS016713 | Embelin ≥98% | 25mg | $93 | 2021-12-16 | Buy |
Arctom | AS016713 | Embelin ≥98% | 50mg | $158 | 2021-12-16 | Buy |
Arctom | SY064447 | 2,5-Dihydroxy-3-undecyl-[1,4]benzoquinone | 10mg | $158.18 | 2021-12-16 | Buy |
Properties
Melting point :142-143°C
Boiling point :356.15°C (rough estimate)
Density :1.131
refractive index :1.4230 (estimate)
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :DMSO: >10 mg/mL
form :solid
pka :2.84±0.50(Predicted)
color :Dark orange
Sensitive :Light Sensitive
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
LogP :5.024 (est)
Boiling point :356.15°C (rough estimate)
Density :1.131
refractive index :1.4230 (estimate)
storage temp. :Keep in dark place,Inert atmosphere,2-8°C
solubility :DMSO: >10 mg/mL
form :solid
pka :2.84±0.50(Predicted)
color :Dark orange
Sensitive :Light Sensitive
Stability :Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
LogP :5.024 (est)
Safety Information
Symbol(GHS): | ||||||||
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Signal word: | Warning | |||||||
Hazard statements: |
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Precautionary statements: |
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Description
X-Linked inhibitor of apoptosis (XIAP) is a protein which modulates several pathways, including several related to apoptosis. Embelin is a natural benzoquinone, isolated from plants of the genus Embelia, which directly binds and inhibits XIAP (IC50 = 4.1 μM). In this way, this cell-permeable inhibitor blocks growth while activating caspases and promoting apoptosis in cancer cells expressing high levels of XIAP. Presumably in an XIAP-dependent fashion, embelin (15-50 μM) also prevents NF-κB activation by inhibiting IKK. This compound also protects against XIAP- and caspase-dependent inflammation.More related product prices
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