CYCLOPIAZONIC ACID
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- $25 - $850
- Product name: CYCLOPIAZONIC ACID
- CAS: 18172-33-3
- MF: C20H20N2O3
- MW: 336.38
- EINECS:
- MDL Number:MFCD00167445
- Synonyms:-Cyclopiazonic acid / CPA;Cyclopiazonic acid from Penicillium grisefulvum;Cyclopiazonic acid (CPA);Cyclopiazonic acid, FroM PenicilliuM griseofulvuM;(6aR,11aS,11bR)-10-acetyl-11-hydroxy-7,7-dimethyl-2,6,6a,7,11a,11b-hexahydro-9H-pyrrolo[1',2':2,3]isoindolo[4,5,6-cd]indol-9-one;(6a-alpha,11a,11b-alpha)--10-acetyl-7-dimethyl-11-hydroxy- ;9h-pyrrolo(1’,2’:2,3)isoindolo(4,5,6-cd)indol-9-one,2,6,6a,7,11a,11b-hexahydro ;(6AA, 10Z, 11AB, 11BA)-6A,7,11A,11B-TETRAHYDRO-10-(1-HYDROXYETHYLIDENE)-7,7- DIMETHYL-6H-PYRROLO [1',2':2,3]ISOINDOLO [4,5,6-CD]INDOLE-9,11 (2H,10H)-DIONE
20 prices
Selected condition：
Brand
- AK Scientific
- Alfa Aesar
- ApexBio Technology
- Biosynth Carbosynth
- Cayman Chemical
- ChemScene
- Sigma-Aldrich
- TRC
Package
- 1mg
- 2mg
- 5mg
- 10mg
- 25mg
- 50mg
- ManufacturerAK Scientific
- Product number8500AJ
- Product descriptionCyclopiazonic Acid,
- Packaging1mg
- Price$125
- Updated2021-12-16
- Buy
- ManufacturerAlfa Aesar
- Product numberJ61594
- Product descriptionCyclopiazonic acid, 98%
- Packaging10mg
- Price$185.65
- Updated2024-03-01
- Buy
- ManufacturerAlfa Aesar
- Product numberJ61594
- Product descriptionCyclopiazonic acid, 98%
- Packaging50mg
- Price$698.65
- Updated2024-03-01
- Buy
- ManufacturerApexBio Technology
- Product numberB6647
- Product descriptionCyclopiazonic Acid,
- Packaging5mg
- Price$79
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB6647
- Product descriptionCyclopiazonic Acid,
- Packaging10mg
- Price$138
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC45557
- Product descriptionCyclopiazonic acid
- Packaging2mg
- Price$80
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC45557
- Product descriptionCyclopiazonic acid
- Packaging5mg
- Price$150
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC45557
- Product descriptionCyclopiazonic acid
- Packaging10mg
- Price$270
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC45557
- Product descriptionCyclopiazonic acid
- Packaging25mg
- Price$550
- Updated2021-12-16
- Buy
- ManufacturerBiosynth Carbosynth
- Product numberFC45557
- Product descriptionCyclopiazonic acid
- Packaging50mg
- Price$850
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number11326
- Product descriptionCyclopiazonic Acid ≥95%
- Packaging1mg
- Price$25
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number11326
- Product descriptionCyclopiazonic Acid ≥95%
- Packaging5mg
- Price$71
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number11326
- Product descriptionCyclopiazonic Acid ≥95%
- Packaging10mg
- Price$121
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0026710
- Product descriptionCyclopiazonic Acid, >99.0%
- Packaging5mg
- Price$250
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0026710
- Product descriptionCyclopiazonic Acid, >99.0%
- Packaging10mg
- Price$430
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product number239805
- Product descriptionCyclopiazonic Acid, A cell-permeable, reversible inhibitor of sarcoplasmic reticulum Ca
- Packaging5mg
- Price$96.4
- Updated2023-01-07
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 8500AJ | Cyclopiazonic Acid, | 1mg | $125 | 2021-12-16 | Buy |
| Alfa Aesar | J61594 | Cyclopiazonic acid, 98% | 10mg | $185.65 | 2024-03-01 | Buy |
| Alfa Aesar | J61594 | Cyclopiazonic acid, 98% | 50mg | $698.65 | 2024-03-01 | Buy |
| ApexBio Technology | B6647 | Cyclopiazonic Acid, | 5mg | $79 | 2021-12-16 | Buy |
| ApexBio Technology | B6647 | Cyclopiazonic Acid, | 10mg | $138 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC45557 | Cyclopiazonic acid | 2mg | $80 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC45557 | Cyclopiazonic acid | 5mg | $150 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC45557 | Cyclopiazonic acid | 10mg | $270 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC45557 | Cyclopiazonic acid | 25mg | $550 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FC45557 | Cyclopiazonic acid | 50mg | $850 | 2021-12-16 | Buy |
| Cayman Chemical | 11326 | Cyclopiazonic Acid ≥95% | 1mg | $25 | 2024-03-01 | Buy |
| Cayman Chemical | 11326 | Cyclopiazonic Acid ≥95% | 5mg | $71 | 2024-03-01 | Buy |
| Cayman Chemical | 11326 | Cyclopiazonic Acid ≥95% | 10mg | $121 | 2024-03-01 | Buy |
| ChemScene | CS-0026710 | Cyclopiazonic Acid, >99.0% | 5mg | $250 | 2021-12-16 | Buy |
| ChemScene | CS-0026710 | Cyclopiazonic Acid, >99.0% | 10mg | $430 | 2021-12-16 | Buy |
| Sigma-Aldrich | 239805 | Cyclopiazonic Acid, A cell-permeable, reversible inhibitor of sarcoplasmic reticulum Ca | 5mg | $96.4 | 2023-01-07 | Buy |
Properties
Melting point :245-246°C
Boiling point :472.86°C (rough estimate)
Density :1.2171 (rough estimate)
refractive index :1.5700 (estimate)
storage temp. :-20°C
solubility :DMSO: soluble
form :powder
pka :4.50±1.00(Predicted)
color :white to off-white
Water Solubility :Soluble in DMSO (100 mM), ethanol (5 mM), DMF (~20 mg/ml), and 1:1 DMSO:PBS(pH 7.2) (0.5 mg/ml). Insoluble in water.
EPA Substance Registry System :Cyclopiazonic acid (18172-33-3)
Boiling point :472.86°C (rough estimate)
Density :1.2171 (rough estimate)
refractive index :1.5700 (estimate)
storage temp. :-20°C
solubility :DMSO: soluble
form :powder
pka :4.50±1.00(Predicted)
color :white to off-white
Water Solubility :Soluble in DMSO (100 mM), ethanol (5 mM), DMF (~20 mg/ml), and 1:1 DMSO:PBS(pH 7.2) (0.5 mg/ml). Insoluble in water.
EPA Substance Registry System :Cyclopiazonic acid (18172-33-3)
Safety Information
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| Signal word: | Danger | ||||||||||||||
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Description
Cyclopiazonic acid is a mycotoxin produced by molds including certain species of Penicillium and Aspergillus. Its toxicity is linked to its ability to specifically and reversibly inhibit sarco-endoplasmic reticulum Ca2+-ATPases (SERCA; IC50 = 0.6 μM). Cyclopiazonic acid does not inhibit a wide variety of other types of membrane-bound ATPases. It effectively inhibits SERCA in intact tissue, in smooth muscle and endothelium, as well as in isolated cells.More related product prices
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