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ChemicalBook >> CAS DataBase List >> COUMESTROL

COUMESTROL

COUMESTROL price.
  • $44 - $2000
  • Product name: COUMESTROL
  • CAS: 479-13-0
  • MF: C15H8O5
  • MW: 268.22
  • EINECS:207-525-6
  • MDL Number:MFCD00016885
  • Synonyms:cumoesterol ;COUMOESTROL;7 12-DIHYDROXYCOUMESTAN 98%;Coumesterol;COUMESTROL(P);2-(2 4-DIHYDROXYPHENYL)-6-HYDROXY-3-BENZOFURANCARBOXYLIC ACID D-LACTONE 98%;Coumestrol,99%;3-Benzofurancarboxylic acid, 2-(2,4-dihydroxyphenyl)-6-hydroxy-, .delta.-lactone
24 prices
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Brand
  • A1 Biochem Labs
  • AHH
  • ApexBio Technology
  • Arctom
  • Biosynth Carbosynth
  • Cayman Chemical
  • DC Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 0.025g
  • 50mg
  • 100mg
  • 250mg
  • 500mg
  • ManufacturerA1 Biochem Labs
  • Product number6563894
  • Product description3,9-Dihydroxy-6H-[1]benzofuro[3,2-c]chromen-6-one 95%
  • Packaging100mg
  • Price$500
  • Updated2021-12-16
  • Buy
  • ManufacturerA1 Biochem Labs
  • Product number6563894
  • Product description3,9-Dihydroxy-6H-[1]benzofuro[3,2-c]chromen-6-one 95%
  • Packaging500mg
  • Price$1200
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberMT-49530
  • Product descriptionCoumestrol 98%
  • Packaging0.025g
  • Price$230
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC5832
  • Product descriptionCoumestrol
  • Packaging5mg
  • Price$104
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberC5832
  • Product descriptionCoumestrol
  • Packaging10mg
  • Price$173
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN96040
  • Product descriptionCoumestrol
  • Packaging10mg
  • Price$178
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberSY232751
  • Product descriptionCoumestrol ≥98%
  • Packaging10mg
  • Price$1699.09
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC20578
  • Product descriptionCoumestrol
  • Packaging5mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC20578
  • Product descriptionCoumestrol
  • Packaging10mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC20578
  • Product descriptionCoumestrol
  • Packaging25mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC20578
  • Product descriptionCoumestrol
  • Packaging50mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC20578
  • Product descriptionCoumestrol
  • Packaging100mg
  • Price$450
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number11730
  • Product descriptionCoumestrol ≥98%
  • Packaging1mg
  • Price$44
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11730
  • Product descriptionCoumestrol ≥98%
  • Packaging5mg
  • Price$93
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11730
  • Product descriptionCoumestrol ≥98%
  • Packaging10mg
  • Price$153
  • Updated2024-03-01
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC10363
  • Product descriptionCoumestrol >98%
  • Packaging250mg
  • Price$1100
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
A1 Biochem Labs 6563894 3,9-Dihydroxy-6H-[1]benzofuro[3,2-c]chromen-6-one 95% 100mg $500 2021-12-16 Buy
A1 Biochem Labs 6563894 3,9-Dihydroxy-6H-[1]benzofuro[3,2-c]chromen-6-one 95% 500mg $1200 2021-12-16 Buy
AHH MT-49530 Coumestrol 98% 0.025g $230 2021-12-16 Buy
ApexBio Technology C5832 Coumestrol 5mg $104 2021-12-16 Buy
ApexBio Technology C5832 Coumestrol 10mg $173 2021-12-16 Buy
Arctom CFN96040 Coumestrol 10mg $178 2021-12-16 Buy
Arctom SY232751 Coumestrol ≥98% 10mg $1699.09 2021-12-16 Buy
Biosynth Carbosynth FC20578 Coumestrol 5mg $60 2021-12-16 Buy
Biosynth Carbosynth FC20578 Coumestrol 10mg $100 2021-12-16 Buy
Biosynth Carbosynth FC20578 Coumestrol 25mg $150 2021-12-16 Buy
Biosynth Carbosynth FC20578 Coumestrol 50mg $250 2021-12-16 Buy
Biosynth Carbosynth FC20578 Coumestrol 100mg $450 2021-12-16 Buy
Cayman Chemical 11730 Coumestrol ≥98% 1mg $44 2024-03-01 Buy
Cayman Chemical 11730 Coumestrol ≥98% 5mg $93 2024-03-01 Buy
Cayman Chemical 11730 Coumestrol ≥98% 10mg $153 2024-03-01 Buy
DC Chemicals DC10363 Coumestrol >98% 250mg $1100 2021-12-16 Buy

Properties

Melting point :≥350 °C(lit.)
Boiling point :331.39°C (rough estimate)
Density :1.2586 (rough estimate)
refractive index :1.7680 (estimate)
storage temp. :Refrigerator
solubility :DMSO: soluble
form :Light beige solid.
pka :8.25±0.20(Predicted)
color :Pale Yellow to Dark Brown
BRN :266702
LogP :2.940 (est)
CAS DataBase Reference :479-13-0(CAS DataBase Reference)
EPA Substance Registry System :Coumestrol (479-13-0)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Coumestrol is a phytoestrogen that occurs naturally in soybeans, spinach, and clover. It competitively (vs. 17β-estradiol, ) binds the estrogen receptors ERα (IC50 = 11 nM) and ERβ (IC50 = 2 nM) and can induce ER-dependent gene expression in isolated cells. Coumestrol is also a weak antagonist of pregnane X receptor (IC50 = 12 μM) as well as a potential inverse agonist of the constitutive androstane receptor (EC50 = 30 μM).

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