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ChemicalBook >> CAS DataBase List >> CONESSINE

CONESSINE

CONESSINE price.
  • $50 - $504
  • Product name: CONESSINE
  • CAS: 546-06-5
  • MF: C24H40N2
  • MW: 356.59
  • EINECS:208-897-2
  • MDL Number:MFCD00016752
  • Synonyms:3-beta-(dimethylamino)-con-5-enin ;3-beta-(dimethylamino)con-5-enine ;n,18-dihydrotrimethyl-conkurchin ;n-dimethyl-(3-beta)-con-5-enin-3-amin ;WRIGHTINE;NERVINE;NERIINE;ROGUESSINE
15 prices
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Brand
  • AK Scientific
  • ApexBio Technology
  • Arctom
  • Biosynth Carbosynth
  • Cayman Chemical
  • Sigma-Aldrich
  • TRC
  • Usbiological
Package
  • 10mg
  • 20mg
  • 25mg
  • 50mg
  • 100mg
  • 250mg
  • ManufacturerAK Scientific
  • Product number7883BA
  • Product descriptionConessine
  • Packaging25mg
  • Price$151
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberB7044
  • Product descriptionConessine
  • Packaging50mg
  • Price$172
  • Updated2021-12-16
  • Buy
  • ManufacturerArctom
  • Product numberCFN70405
  • Product descriptionConessine ≥98%
  • Packaging20mg
  • Price$70
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC57645
  • Product descriptionConessine
  • Packaging10mg
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC57645
  • Product descriptionConessine
  • Packaging25mg
  • Price$75
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC57645
  • Product descriptionConessine
  • Packaging50mg
  • Price$100
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC57645
  • Product descriptionConessine
  • Packaging100mg
  • Price$150
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFC57645
  • Product descriptionConessine
  • Packaging250mg
  • Price$250
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number11700
  • Product descriptionConessine ≥98%
  • Packaging50mg
  • Price$120
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11700
  • Product descriptionConessine ≥98%
  • Packaging100mg
  • Price$228
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number11700
  • Product descriptionConessine ≥98%
  • Packaging250mg
  • Price$504
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0095
  • Product descriptionConessine ≥97% (HPLC)
  • Packaging10mg
  • Price$53.4
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberSML0095
  • Product descriptionConessine ≥97% (HPLC)
  • Packaging50mg
  • Price$193
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberC670500
  • Product descriptionConessine
  • Packaging10mg
  • Price$105
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number255027
  • Product descriptionConessine
  • Packaging50mg
  • Price$395
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 7883BA Conessine 25mg $151 2021-12-16 Buy
ApexBio Technology B7044 Conessine 50mg $172 2021-12-16 Buy
Arctom CFN70405 Conessine ≥98% 20mg $70 2021-12-16 Buy
Biosynth Carbosynth FC57645 Conessine 10mg $50 2021-12-16 Buy
Biosynth Carbosynth FC57645 Conessine 25mg $75 2021-12-16 Buy
Biosynth Carbosynth FC57645 Conessine 50mg $100 2021-12-16 Buy
Biosynth Carbosynth FC57645 Conessine 100mg $150 2021-12-16 Buy
Biosynth Carbosynth FC57645 Conessine 250mg $250 2021-12-16 Buy
Cayman Chemical 11700 Conessine ≥98% 50mg $120 2024-03-01 Buy
Cayman Chemical 11700 Conessine ≥98% 100mg $228 2024-03-01 Buy
Cayman Chemical 11700 Conessine ≥98% 250mg $504 2024-03-01 Buy
Sigma-Aldrich SML0095 Conessine ≥97% (HPLC) 10mg $53.4 2024-03-01 Buy
Sigma-Aldrich SML0095 Conessine ≥97% (HPLC) 50mg $193 2024-03-01 Buy
TRC C670500 Conessine 10mg $105 2021-12-16 Buy
Usbiological 255027 Conessine 50mg $395 2021-12-16 Buy

Properties

Melting point :126-127°C
alpha :D20 +25.3° (c = 0.7 in abs alc)
Boiling point :479.38°C (rough estimate)
Density :0.9492 (rough estimate)
refractive index :1.5640 (estimate)
storage temp. :Store at RT
solubility :ethanol: ≥2mg/mL
form :powder
pka :10.20±0.70(Predicted)
color :white to tan
optical activity :+25.320 (c 0.7, ethanol)
LogP :6.060 (est)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Conessine is a naturally occurring steroid alkaloid found in a number of plant species from the Apocynaceae family, which have been used in traditional herbal medicine as a treatment for amoebic dysentery. In a radioligand-based high-throughput screen, conessine demonstrated high affinity for both rat and human histamine H3 receptors (Kis = 5.2 and 24.5 nM, respectively) and high selectivity against histamine receptors H1, H2, and H4. Though conessine potently blocks H3 agonist-stimulated GTPγS binding in cell- and tissue-based functional assays and efficiently crosses the blood-brain barrier, it has a poor rate of CNS clearance.

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