BORRELIDIN
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- $81 - $1332
- Product name: BORRELIDIN
- CAS: 7184-60-3
- MF: C28H43NO6
- MW: 489.64
- EINECS:
- MDL Number:MFCD08276914
- Synonyms:2-(7-CYANO-8,16-DIHYDROXY-9,11,13,15-TETRAMETHYL-18-OXOOXACYCLOOCTADECA-4,6-DIEN-2-YL)-CYCLOPENTANECARBOXYLIC ACID;BORRELIDIN;BORRELIDINE;2-(7-Cyano-8,16-dihydroxy-9,11,13,15-tetramethyl-18-oxo-1-oxacyclooctadeca-4,6-dien-2-yl)cyclopentane-1-carboxylic acid;Aids128115;Aids-128115;Cyclopentanecarboxylic acid, 2-(7-cyano-8, 16-dihydroxy-9,11,13,15-tetramethyl-18-oxooxacyclooctadeca-4, 6-dien-2-yl)-;Quinquangulin K 031
18 prices
Selected condition：
Brand
- Adipogen Life Sciences
- AK Scientific
- ApexBio Technology
- Biorbyt Ltd
- Cayman Chemical
- ChemScene
- Sigma-Aldrich
- Tocris
- TRC
- Usbiological
Package
- 500μg
- 1mg
- 500ug
- 1
- 5mg
- 10mg
- ManufacturerAdipogen Life Sciences
- Product numberBVT-0098-M005
- Product descriptionBorrelidin ≥98%(HPLC)
- Packaging5mg
- Price$360
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number8443AJ
- Product descriptionBorrelidin
- Packaging5mg
- Price$860
- Updated2021-12-16
- Buy
- ManufacturerAK Scientific
- Product number8443AJ
- Product descriptionBorrelidin
- Packaging10mg
- Price$1332
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7699
- Product descriptionBorrelidin
- Packaging500ug
- Price$410
- Updated2021-12-16
- Buy
- ManufacturerApexBio Technology
- Product numberB7699
- Product descriptionBorrelidin
- Packaging1mg
- Price$693
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545895
- Product descriptionborrelidin >98%
- Packaging1mg
- Price$372.3
- Updated2021-12-16
- Buy
- ManufacturerBiorbyt Ltd
- Product numberorb545895
- Product descriptionborrelidin >98%
- Packaging5mg
- Price$1315.8
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number14436
- Product descriptionBorrelidin ≥98%
- Packaging500μg
- Price$81
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number14436
- Product descriptionBorrelidin ≥98%
- Packaging1mg
- Price$122
- Updated2024-03-01
- Buy
- ManufacturerChemScene
- Product numberCS-0011785
- Product descriptionBorrelidin >98.0%
- Packaging500ug
- Price$200
- Updated2021-12-16
- Buy
- ManufacturerChemScene
- Product numberCS-0011785
- Product descriptionBorrelidin >98.0%
- Packaging1mg
- Price$340
- Updated2021-12-16
- Buy
- ManufacturerSigma-Aldrich
- Product numberB3061
- Product descriptionBorrelidin from Streptomyces parvulus, ≥98% (HPLC)
- Packaging1mg
- Price$648
- Updated2024-03-01
- Buy
- ManufacturerTocris
- Product number4706
- Product descriptionBorrelidin ≥98%(HPLC)
- Packaging1
- Price$316
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberB675390
- Product descriptionBorrelidin
- Packaging1mg
- Price$370
- Updated2021-12-16
- Buy
- ManufacturerTRC
- Product numberB675390
- Product descriptionBorrelidin
- Packaging5mg
- Price$1300
- Updated2021-12-16
- Buy
- ManufacturerUsbiological
- Product number207093
- Product descriptionBorrelidin
- Packaging500ug
- Price$316
- Updated2021-12-16
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| Adipogen Life Sciences | BVT-0098-M005 | Borrelidin ≥98%(HPLC) | 5mg | $360 | 2021-12-16 | Buy |
| AK Scientific | 8443AJ | Borrelidin | 5mg | $860 | 2021-12-16 | Buy |
| AK Scientific | 8443AJ | Borrelidin | 10mg | $1332 | 2021-12-16 | Buy |
| ApexBio Technology | B7699 | Borrelidin | 500ug | $410 | 2021-12-16 | Buy |
| ApexBio Technology | B7699 | Borrelidin | 1mg | $693 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb545895 | borrelidin >98% | 1mg | $372.3 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb545895 | borrelidin >98% | 5mg | $1315.8 | 2021-12-16 | Buy |
| Cayman Chemical | 14436 | Borrelidin ≥98% | 500μg | $81 | 2024-03-01 | Buy |
| Cayman Chemical | 14436 | Borrelidin ≥98% | 1mg | $122 | 2024-03-01 | Buy |
| ChemScene | CS-0011785 | Borrelidin >98.0% | 500ug | $200 | 2021-12-16 | Buy |
| ChemScene | CS-0011785 | Borrelidin >98.0% | 1mg | $340 | 2021-12-16 | Buy |
| Sigma-Aldrich | B3061 | Borrelidin from Streptomyces parvulus, ≥98% (HPLC) | 1mg | $648 | 2024-03-01 | Buy |
| Tocris | 4706 | Borrelidin ≥98%(HPLC) | 1 | $316 | 2021-12-16 | Buy |
| TRC | B675390 | Borrelidin | 1mg | $370 | 2021-12-16 | Buy |
| TRC | B675390 | Borrelidin | 5mg | $1300 | 2021-12-16 | Buy |
| Usbiological | 207093 | Borrelidin | 500ug | $316 | 2021-12-16 | Buy |
Properties
Melting point :143-145℃
Boiling point :584.45°C (rough estimate)
Density :1.1362 (rough estimate)
refractive index :1.6290 (estimate)
storage temp. :−20°C
solubility :DMSO: 1 mg/mL
form :White to off-white powder.
pka :4.56±0.40(Predicted)
color :Off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Boiling point :584.45°C (rough estimate)
Density :1.1362 (rough estimate)
refractive index :1.6290 (estimate)
storage temp. :−20°C
solubility :DMSO: 1 mg/mL
form :White to off-white powder.
pka :4.56±0.40(Predicted)
color :Off-white
Stability :Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
Safety Information
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Description
Borrelidin is a secondary metabolite produced by Streptomyces and other bacteria. It displays potent antiangiogenic activity, preventing tube formation in rat aorta explants (IC50 = 0.8 nM) and inducing apoptosis in endothelial cells. Borrelidin also alters the splicing of VEGF mRNA, producing an antiangiogenic isoform of the growth factor. It has long been known as a powerful inhibitor of both eukaryotic and bacterial threonyl tRNA synthetase. Borrelidin is also an effective anti-malarial drug, as it kills P. falciparum with an IC50 value of 1.8 nM. At higher doses, it inhibits cyclin-dependent kinase in yeast (IC50 = 24 μM), resulting in growth arrest in the G1 phase.More related product prices
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