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ChemicalBook >> CAS DataBase List >> BI-6C9

BI-6C9

BI-6C9 price.
  • $55 - $900
  • Product name: BI-6C9
  • CAS: 791835-21-7
  • MF: C23H25N3O4S2
  • MW: 471.59
  • EINECS:
  • MDL Number:MFCD07784498
  • Synonyms:N-[4-(4-aminophenyl)sulfanylphenyl]-4-[(4-methoxyphenyl)sulfonylamino]butanamide;Butanamide, N-[4-[(4-aminophenyl)thio]phenyl]-4-[[(4-methoxyphenyl)sulfonyl]amino]-;N-(4-((4-Aminophenyl)thio)phenyl)-4-(4-methoxyphenylsulfonamido)butanamide;Inhibitor,fission,Neurodegeneration,Bid,BI6C9,BI 6C9,Mitochodondrial,death,Mitochondria,Apoptosis,inhibit,Glutamate,stress,Neuronal,Bcl-2,Mitochondrial,Mitochondrial Metabolism,potential,cell,Oxidative,membrane,BI-6C9,BI-6C-9;BI-6C9, 10 mM in DMSO
13 prices
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • Cayman Chemical
  • ChemScene
  • Sigma-Aldrich
  • TRC
Package
  • 1mg
  • 5mg
  • 10mg
  • 50mg
  • ManufacturerAK Scientific
  • Product number8956CS
  • Product descriptionN-[4-(4-Aminophenyl)sulfanylphenyl]-4-[(4-methoxyphenyl)sulfonylamino]butanamide
  • Packaging1mg
  • Price$159
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product number8956CS
  • Product descriptionN-[4-(4-Aminophenyl)sulfanylphenyl]-4-[(4-methoxyphenyl)sulfonylamino]butanamide
  • Packaging5mg
  • Price$367
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0005465
  • Product descriptionBI-6C9 95.00%
  • Packaging1MG
  • Price$459
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0005465
  • Product descriptionBI-6C9 95.00%
  • Packaging5MG
  • Price$812.48
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number17265
  • Product descriptionBI-6C9 ≥98%
  • Packaging1mg
  • Price$56
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17265
  • Product descriptionBI-6C9 ≥98%
  • Packaging5mg
  • Price$241
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17265
  • Product descriptionBI-6C9 ≥98%
  • Packaging10mg
  • Price$429
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0029592
  • Product descriptionBI-6C9 98.24%
  • Packaging5mg
  • Price$180
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0029592
  • Product descriptionBI-6C9 98.24%
  • Packaging10mg
  • Price$300
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0029592
  • Product descriptionBI-6C9 98.24%
  • Packaging50mg
  • Price$900
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberB0186
  • Product descriptionBI-6C9 ≥97% (HPLC), solid
  • Packaging1mg
  • Price$93.4
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberB0186
  • Product descriptionBI-6C9 ≥97% (HPLC), solid
  • Packaging5mg
  • Price$324
  • Updated2024-03-01
  • Buy
  • ManufacturerTRC
  • Product numberB591705
  • Product descriptionBI-6C9
  • Packaging1mg
  • Price$55
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 8956CS N-[4-(4-Aminophenyl)sulfanylphenyl]-4-[(4-methoxyphenyl)sulfonylamino]butanamide 1mg $159 2021-12-16 Buy
AK Scientific 8956CS N-[4-(4-Aminophenyl)sulfanylphenyl]-4-[(4-methoxyphenyl)sulfonylamino]butanamide 5mg $367 2021-12-16 Buy
American Custom Chemicals Corporation INB0005465 BI-6C9 95.00% 1MG $459 2021-12-16 Buy
American Custom Chemicals Corporation INB0005465 BI-6C9 95.00% 5MG $812.48 2021-12-16 Buy
Cayman Chemical 17265 BI-6C9 ≥98% 1mg $56 2024-03-01 Buy
Cayman Chemical 17265 BI-6C9 ≥98% 5mg $241 2024-03-01 Buy
Cayman Chemical 17265 BI-6C9 ≥98% 10mg $429 2024-03-01 Buy
ChemScene CS-0029592 BI-6C9 98.24% 5mg $180 2021-12-16 Buy
ChemScene CS-0029592 BI-6C9 98.24% 10mg $300 2021-12-16 Buy
ChemScene CS-0029592 BI-6C9 98.24% 50mg $900 2021-12-16 Buy
Sigma-Aldrich B0186 BI-6C9 ≥97% (HPLC), solid 1mg $93.4 2024-03-01 Buy
Sigma-Aldrich B0186 BI-6C9 ≥97% (HPLC), solid 5mg $324 2024-03-01 Buy
TRC B591705 BI-6C9 1mg $55 2021-12-16 Buy

Properties

Density :1.36±0.1 g/cm3(Predicted)
storage temp. :Keep in dark place,Sealed in dry,Store in freezer, under -20°C
solubility :DMSO: 24 mg/mL, soluble
form :solid
pka :11.58±0.50(Predicted)
color :off-white

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

BH3-interacting domain (Bid) is cleaved by caspase-8 to produce the truncated protein tBid, which facilitates cytochrome c release from mitochondria and drives apoptosis. BI-6C9 is an inhibitor of tBid (Kd = 20 μM), blocking the release of both cytochrome c and second mitochondria-derived activator of caspase from mitochondria. It prevents apoptosis in neurons treated with glutamate or oxygen-glucose deprivation. BI-6C9 (10 μM) also inhibits the nuclear translocation of apoptosis-inducing factor AIF, preventing the death of ovarian OVCAR-3 cancer cells induced by IFN-α2a.