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ChemicalBook >> CAS DataBase List >> (5S,6Z,8E,10E,12R,14Z)-5,12-dihydroxy-N-(2-hydroxyethyl)icosa-6,8,10,14-tetraenamide

(5S,6Z,8E,10E,12R,14Z)-5,12-dihydroxy-N-(2-hydroxyethyl)icosa-6,8,10,14-tetraenamide

(5S,6Z,8E,10E,12R,14Z)-5,12-dihydroxy-N-(2-hydroxyethyl)icosa-6,8,10,14-tetraenamide price.
3 prices
Selected condition：
Brand
  • Cayman Chemical
Package
  • 25μg
  • 50μg
  • 100μg
  • ManufacturerCayman Chemical
  • Product number20112
  • Product descriptionLeukotriene B4 Ethanolamide ≥97%
  • Packaging25μg
  • Price$150
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number20112
  • Product descriptionLeukotriene B4 Ethanolamide ≥97%
  • Packaging50μg
  • Price$262
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number20112
  • Product descriptionLeukotriene B4 Ethanolamide ≥97%
  • Packaging100μg
  • Price$493
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Cayman Chemical 20112 Leukotriene B4 Ethanolamide ≥97% 25μg $150 2024-03-01 Buy
Cayman Chemical 20112 Leukotriene B4 Ethanolamide ≥97% 50μg $262 2024-03-01 Buy
Cayman Chemical 20112 Leukotriene B4 Ethanolamide ≥97% 100μg $493 2024-03-01 Buy

Properties

Boiling point :617.6±55.0 °C(Predicted)
Density :1.038±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 100 mg/ml; DMSO: 100 mg/ml; Ethanol: 100 mg/ml; PBS (pH 7.2): 12 mg/ml
pka :13.82±0.20(Predicted)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger GHS hazard pictograms P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233 Keep container tightly closed.
P240 Ground/bond container and receiving equipment.
P241 Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242 Use only non-sparking tools.
P243 Take precautionary measures against static discharge.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P370+P378 In case of fire: Use … for extinction.
P403+P235 Store in a well-ventilated place. Keep cool.
P501 Dispose of contents/container to..…

Description

The effects of Leukotriene B4 (LTB4) are mediated by two known receptors, BLT1 and BLT2. LTB4 is a high affinity ligand for BLT1, and many of its pro-inflammatory effects are believed to be transduced through this receptor. The BLT2 is more enigmatic, in that LTB4 is not a high-affinity ligand, nor is it clear that BLT2 activation promotes inflammation. LTB4 ethanolamide (LTB4-EA) is a theoretical 5-LO metabolite of arachidonoyl ethanolamide (AEA). In CHO cells transfected with human BLTR1, LTB4-EA was a potent antagonist with about three times greater affinity for the receptor than LTB4 (Ki = 1.22 nM versus 3.88 nM). LTB4-EA antagonizes the LTB4-induced contractions of guinea pig lung parenchyma with an EC50 of 10 nM. LTB4-EA thus represents a potential endogenous anti-inflammatory compound functioning as a natural antagonist of BLTR1.