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ChemicalBook >> CAS DataBase List >> [4-Amino-2-[(1-methylsulfonylpiperidin-4-yl)amino]pyrimidin-5-yl](2,3-difluoro-6-methoxyphenyl)methanone(R 547)

[4-Amino-2-[(1-methylsulfonylpiperidin-4-yl)amino]pyrimidin-5-yl](2,3-difluoro-6-methoxyphenyl)methanone(R 547)

[4-Amino-2-[(1-methylsulfonylpiperidin-4-yl)amino]pyrimidin-5-yl](2,3-difluoro-6-methoxyphenyl)methanone(R 547) price.
  • $120 - $3200
  • Product name: [4-Amino-2-[(1-methylsulfonylpiperidin-4-yl)amino]pyrimidin-5-yl](2,3-difluoro-6-methoxyphenyl)methanone(R 547)
  • CAS: 741713-40-6
  • MF: C18H21F2N5O4S
  • MW: 441.45
  • EINECS:
  • MDL Number:MFCD09970629
  • Synonyms:[4-Amino-2-[(1-methylsulfonylpiperidin-4-yl)amino]pyrimidin-5-yl](2,3-difluoro-6-methoxyphenyl)methanone(R 547);R547;[4-Amino-2-[(1-methylsulfonylpiperidin-4-yl)amino]pyrimidin-5-yl](2,3-difluoro-6-methoxyphenyl)methanone;Ro 4584820;[4-aMino-2-[[1-(Methylsulfonyl)-4-piperidinyl]aMino]-5-pyriMidinyl](2;3-difluoro-6-Methoxyphenyl)-;R547(Ro 4584820);5-[(2,3-difluoro-6-Methoxyphenyl)carbonyl]-2-N-(1-Methanesulfonylpiperidin-4-yl)pyriMidine-2,4-diaMine
17 prices
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Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Axon Medchem
  • Cayman Chemical
  • Chemenu
  • ChemScene
  • Crysdot
  • DC Chemicals
  • Tocris
Package
  • 10
  • 1mg
  • 5mg
  • 10mg
  • 25mg
  • 50mg
  • 2x25mg
  • 100mg
  • 250mg
  • 1g
  • ManufacturerAK Scientific
  • Product numberY0369
  • Product descriptionR547
  • Packaging1mg
  • Price$232
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberY0369
  • Product descriptionR547
  • Packaging5mg
  • Price$695
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0030159
  • Product description[4-AMINO-2-[(1-METHYLSULFONYLPIPERIDIN-4-YL)AMINO]PYRIMIDIN-5-YL](2,3-DIFLUORO-6-METHOXYPHENYL)METHANONE 95.00%
  • Packaging1MG
  • Price$225.75
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberHCH0030159
  • Product description[4-AMINO-2-[(1-METHYLSULFONYLPIPERIDIN-4-YL)AMINO]PYRIMIDIN-5-YL](2,3-DIFLUORO-6-METHOXYPHENYL)METHANONE 95.00%
  • Packaging5MG
  • Price$499.85
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8642
  • Product descriptionR547
  • Packaging10mg
  • Price$270
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA8642
  • Product descriptionR547
  • Packaging100mg
  • Price$1001
  • Updated2021-12-16
  • Buy
  • ManufacturerAxon Medchem
  • Product numberAxon1983
  • Product descriptionR547 99%
  • Packaging2x25mg
  • Price$484
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number17905
  • Product descriptionR547 ≥98%
  • Packaging1mg
  • Price$120
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number17905
  • Product descriptionR547 ≥98%
  • Packaging5mg
  • Price$537
  • Updated2024-03-01
  • Buy
  • ManufacturerChemenu
  • Product numberCM167858
  • Product description(4-Amino-2-((1-(methylsulfonyl)piperidin-4-yl)amino)pyrimidin-5-yl)(2,3-difluoro-6-methoxyphenyl)methanone 98%
  • Packaging100mg
  • Price$1421
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0022
  • Product descriptionR547 99.66%
  • Packaging10mg
  • Price$190
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-0022
  • Product descriptionR547 99.66%
  • Packaging50mg
  • Price$700
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31000911
  • Product descriptionR547 98+%
  • Packaging25mg
  • Price$608
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31000911
  • Product descriptionR547 98+%
  • Packaging100mg
  • Price$1520
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC2068
  • Product descriptionR547 >98%
  • Packaging250mg
  • Price$1900
  • Updated2021-12-16
  • Buy
  • ManufacturerDC Chemicals
  • Product numberDC2068
  • Product descriptionR547 >98%
  • Packaging1g
  • Price$3200
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific Y0369 R547 1mg $232 2021-12-16 Buy
AK Scientific Y0369 R547 5mg $695 2021-12-16 Buy
American Custom Chemicals Corporation HCH0030159 [4-AMINO-2-[(1-METHYLSULFONYLPIPERIDIN-4-YL)AMINO]PYRIMIDIN-5-YL](2,3-DIFLUORO-6-METHOXYPHENYL)METHANONE 95.00% 1MG $225.75 2021-12-16 Buy
American Custom Chemicals Corporation HCH0030159 [4-AMINO-2-[(1-METHYLSULFONYLPIPERIDIN-4-YL)AMINO]PYRIMIDIN-5-YL](2,3-DIFLUORO-6-METHOXYPHENYL)METHANONE 95.00% 5MG $499.85 2021-12-16 Buy
ApexBio Technology A8642 R547 10mg $270 2021-12-16 Buy
ApexBio Technology A8642 R547 100mg $1001 2021-12-16 Buy
Axon Medchem Axon1983 R547 99% 2x25mg $484 2021-12-16 Buy
Cayman Chemical 17905 R547 ≥98% 1mg $120 2024-03-01 Buy
Cayman Chemical 17905 R547 ≥98% 5mg $537 2024-03-01 Buy
Chemenu CM167858 (4-Amino-2-((1-(methylsulfonyl)piperidin-4-yl)amino)pyrimidin-5-yl)(2,3-difluoro-6-methoxyphenyl)methanone 98% 100mg $1421 2021-12-16 Buy
ChemScene CS-0022 R547 99.66% 10mg $190 2021-12-16 Buy
ChemScene CS-0022 R547 99.66% 50mg $700 2021-12-16 Buy
Crysdot CD31000911 R547 98+% 25mg $608 2021-12-16 Buy
Crysdot CD31000911 R547 98+% 100mg $1520 2021-12-16 Buy
DC Chemicals DC2068 R547 >98% 250mg $1900 2021-12-16 Buy
DC Chemicals DC2068 R547 >98% 1g $3200 2021-12-16 Buy

Properties

Boiling point :703.7±70.0 °C(Predicted)
Density :1.49
storage temp. :Store at -20°C
solubility :Soluble in DMSO
form :crystalline solid
pka :4.22±0.10(Predicted)
color :White to off-white

Safety Information

Symbol(GHS):
Signal word:
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
Precautionary statements:

Description

R547 is a potent ATP-competitive inhibitor of CDK1/2/4 with Ki of 2 nM/3 nM/1 nM. It is less potent to CDK7 and GSK3α/β, while inactive to other kinases. Phase 1.

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