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ChemicalBook >> CAS DataBase List >> 5-Aza-2'-deoxycytidine

5-Aza-2'-deoxycytidine

5-Aza-2'-deoxycytidine price.
  • $13 - $2480
  • Product name: 5-Aza-2'-deoxycytidine
  • CAS: 2353-33-5
  • MF: C8H12N4O4
  • MW: 228.21
  • EINECS:219-089-4
  • MDL Number:MFCD00043011
  • Synonyms:4-Amino-1-(2-deoxy-β-D-erythro-pentofuranosyl)-1,3,5-triazin-2(1H)-one;5-Aza-2'-deoxycytidine,98+%;4-Amino-1-(2-deoxy-β-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one;Decitabine(NSC127716);4-amino-1-(2-deoxy-beta-d-erythro-pentofuranosyl)-s-triazin-2(1h)-on ;4-amino-1-(2-deoxy-beta-d-erythro-pentofuranosyl)-s-triazin-2(1h)-one ;5-azadeoxycytidine ;5-triazin-2(1h)-one,4-amino-1-(2-deoxy-beta-d-erythro-pentofuranosyl)-3
83 prices
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Brand
  • Adipogen Life Sciences
  • AHH
  • AK Scientific
  • Alfa Aesar
  • Ambeed
  • American Custom Chemicals Corporation
  • ApexBio Technology
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  • Arctom
  • AvaChem
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  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Sigma-Aldrich
  • TCI Chemical
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  • Usbiological
Package
  • 10mM(in 1mL DMSO)
  • 5mg
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  • ManufacturerAdipogen Life Sciences
  • Product numberCDX-A0563-M010
  • Product descriptionDecitabine ≥99%(HPLC)
  • Packaging10mg
  • Price$65
  • Updated2021-12-16
  • Buy
  • ManufacturerAHH
  • Product numberAPI-1235
  • Product descriptionDecitabine 98%
  • Packaging0.1g
  • Price$280
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ10097
  • Product descriptionDecitabine
  • Packaging100mg
  • Price$187
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ51735
  • Product descriptionDecitabine
  • Packaging1g
  • Price$225
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ65513
  • Product description5-Aza-2'-deoxycytidine, 98%
  • Packaging100mg
  • Price$279
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberJ65513
  • Product description5-Aza-2'-deoxycytidine, 98%
  • Packaging250mg
  • Price$540.65
  • Updated2024-03-01
  • Buy
  • ManufacturerAmbeed
  • Product numberA156645
  • Product description4-Amino-1-((2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,3,5-triazin-2(1H)-one 99+%
  • Packaging5mg
  • Price$13
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA156645
  • Product description4-Amino-1-((2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,3,5-triazin-2(1H)-one 99+%
  • Packaging10mg
  • Price$17
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA156645
  • Product description4-Amino-1-((2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,3,5-triazin-2(1H)-one 99+%
  • Packaging50mg
  • Price$28
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA156645
  • Product description4-Amino-1-((2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,3,5-triazin-2(1H)-one 99+%
  • Packaging100mg
  • Price$40
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA156645
  • Product description4-Amino-1-((2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,3,5-triazin-2(1H)-one 99+%
  • Packaging250mg
  • Price$60
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA156645
  • Product description4-Amino-1-((2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,3,5-triazin-2(1H)-one 99+%
  • Packaging1g
  • Price$225
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA156645
  • Product description4-Amino-1-((2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,3,5-triazin-2(1H)-one 99+%
  • Packaging5g
  • Price$705
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002229
  • Product descriptionDECITABINE 95.00%
  • Packaging5MG
  • Price$514
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002229
  • Product descriptionDECITABINE 95.00%
  • Packaging25MG
  • Price$645.45
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberAPI0002229
  • Product descriptionDECITABINE 95.00%
  • Packaging250MG
  • Price$2194.5
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
Adipogen Life Sciences CDX-A0563-M010 Decitabine ≥99%(HPLC) 10mg $65 2021-12-16 Buy
AHH API-1235 Decitabine 98% 0.1g $280 2021-12-16 Buy
AK Scientific J10097 Decitabine 100mg $187 2021-12-16 Buy
AK Scientific J51735 Decitabine 1g $225 2021-12-16 Buy
Alfa Aesar J65513 5-Aza-2'-deoxycytidine, 98% 100mg $279 2024-03-01 Buy
Alfa Aesar J65513 5-Aza-2'-deoxycytidine, 98% 250mg $540.65 2024-03-01 Buy
Ambeed A156645 4-Amino-1-((2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,3,5-triazin-2(1H)-one 99+% 5mg $13 2021-12-16 Buy
Ambeed A156645 4-Amino-1-((2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,3,5-triazin-2(1H)-one 99+% 10mg $17 2021-12-16 Buy
Ambeed A156645 4-Amino-1-((2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,3,5-triazin-2(1H)-one 99+% 50mg $28 2021-12-16 Buy
Ambeed A156645 4-Amino-1-((2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,3,5-triazin-2(1H)-one 99+% 100mg $40 2021-12-16 Buy
Ambeed A156645 4-Amino-1-((2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,3,5-triazin-2(1H)-one 99+% 250mg $60 2021-12-16 Buy
Ambeed A156645 4-Amino-1-((2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,3,5-triazin-2(1H)-one 99+% 1g $225 2021-12-16 Buy
Ambeed A156645 4-Amino-1-((2S,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-1,3,5-triazin-2(1H)-one 99+% 5g $705 2021-12-16 Buy
American Custom Chemicals Corporation API0002229 DECITABINE 95.00% 5MG $514 2021-12-16 Buy
American Custom Chemicals Corporation API0002229 DECITABINE 95.00% 25MG $645.45 2021-12-16 Buy
American Custom Chemicals Corporation API0002229 DECITABINE 95.00% 250MG $2194.5 2021-12-16 Buy

Properties

Melting point :~200 °C (dec.)
alpha :D22 +68.5° (30 min) +57.8° (6 hr) (c = 0.5 in water)
Boiling point :370.01°C (rough estimate)
Density :1.3771 (rough estimate)
refractive index :1.6590 (estimate)
storage temp. :Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility :acetic acid/water (1:1): 50 mg/mL
pka :14.02±0.60(Predicted)
form :Powder
color :White to Off-white
Merck :14,2853
BRN :617982
Stability :Stable. May be light or air sensitive. Incompatible with strong oxidizing agents.
InChIKey :XAUDJQYHKZQPEU-KVQBGUIXSA-N
CAS DataBase Reference :2353-33-5(CAS DataBase Reference)
EPA Substance Registry System :

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
H341 Suspected of causing genetic defects Germ cell mutagenicity Category 2 Warning P201,P202, P281, P308+P313, P405,P501
H360 May damage fertility or the unborn child Reproductive toxicity Category 1A, 1B Danger GHS hazard pictograms
Precautionary statements:
P201 Obtain special instructions before use.
P202 Do not handle until all safety precautions have been read and understood.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313 IF exposed or concerned: Get medical advice/attention.

Description

5-Azacytidine is an analog of cytidine which can be incorporated into DNA, inhibit DNA methyltransferases, and cause hypomethylation of cytosine residues in the absence of any significant mutagenic effects. Decitabine is a 2’-deoxy analog of 5-azacytidine which similarly causes hypomethylation of DNA by inhibiting DNA methyltransferases in a concentration-dependent manner. This action is useful in conditions characterized by DNA hypermethylation, as is found in myelodysplastic syndromes.

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