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ChemicalBook >> CAS DataBase List >> Phenylmethylsulfonyl fluoride

Phenylmethylsulfonyl fluoride

Phenylmethylsulfonyl fluoride price.
  • $5 - $2530
  • Product name: Phenylmethylsulfonyl fluoride
  • CAS: 329-98-6
  • MF: C7H7FO2S
  • MW: 174.19
  • EINECS:206-350-2
  • MDL Number:MFCD00007424
  • Synonyms:α-toluenesulphonyl fluoride;Phenylmethanesulfonyl fluoride,α-Toluenesulfonyl fluoride, Benzylsulfonyl fluoride, PMSF, Phenylmethylsulfonyl fluoride;Phenylmethanesulfony;BENZYLSULFONYL FLUORIDE;A-TOLUENESULFONYL FLUORIDE;A-TOLUENESULPHONYL FLUORIDE;BENZENEMETHANESULFONYL FLUORIDE;P-TOLUENESULPHONYL FLUORIDE
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  • ManufacturerAK Scientific
  • Product numberJ55649
  • Product descriptionalpha-Toluenesulfonylfluoride
  • Packaging5g
  • Price$27
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberB22146
  • Product descriptionalpha-Toluenesulfonyl fluoride, 99%
  • Packaging1g
  • Price$30.4
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberB22146
  • Product descriptionalpha-Toluenesulfonyl fluoride, 99%
  • Packaging5g
  • Price$79.9
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberB22146
  • Product descriptionalpha-Toluenesulfonyl fluoride, 99%
  • Packaging25g
  • Price$289
  • Updated2024-03-01
  • Buy
  • ManufacturerAmbeed
  • Product numberA767839
  • Product descriptionPhenylmethanesulfonyl fluoride 95%
  • Packaging250mg
  • Price$5
  • Updated2021-12-16
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  • ManufacturerAmbeed
  • Product numberA767839
  • Product descriptionPhenylmethanesulfonyl fluoride 95%
  • Packaging1g
  • Price$7
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2587
  • Product descriptionPMSF
  • Packaging10g
  • Price$50
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA2587
  • Product descriptionPMSF
  • Packaging10mM(in 1mL DMSO)
  • Price$55
  • Updated2021-12-16
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  • ManufacturerApexBio Technology
  • Product numberA2587
  • Product descriptionPMSF
  • Packaging100g
  • Price$270
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberPC6222M
  • Product descriptionPhenylmethanesulphonylfluoride 99%
  • Packaging25g
  • Price$50
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberBIP0329
  • Product descriptionPhenylmethanesulphonylfluoride 99%
  • Packaging25g
  • Price$50
  • Updated2021-12-16
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  • ManufacturerApolloscientific
  • Product numberBIP0329
  • Product descriptionPhenylmethanesulphonylfluoride 99%
  • Packaging100g
  • Price$148
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberPC6222M
  • Product descriptionPhenylmethanesulphonylfluoride 99%
  • Packaging100g
  • Price$148
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberPC6222M
  • Product descriptionPhenylmethanesulphonylfluoride 99%
  • Packaging250g
  • Price$327
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberBIP0329
  • Product descriptionPhenylmethanesulphonylfluoride 99%
  • Packaging250g
  • Price$327
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number14333
  • Product descriptionPhenylmethylsulfonyl fluoride ≥98%
  • Packaging5g
  • Price$32
  • Updated2024-03-01
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J55649 alpha-Toluenesulfonylfluoride 5g $27 2021-12-16 Buy
Alfa Aesar B22146 alpha-Toluenesulfonyl fluoride, 99% 1g $30.4 2024-03-01 Buy
Alfa Aesar B22146 alpha-Toluenesulfonyl fluoride, 99% 5g $79.9 2024-03-01 Buy
Alfa Aesar B22146 alpha-Toluenesulfonyl fluoride, 99% 25g $289 2024-03-01 Buy
Ambeed A767839 Phenylmethanesulfonyl fluoride 95% 250mg $5 2021-12-16 Buy
Ambeed A767839 Phenylmethanesulfonyl fluoride 95% 1g $7 2021-12-16 Buy
ApexBio Technology A2587 PMSF 10g $50 2021-12-16 Buy
ApexBio Technology A2587 PMSF 10mM(in 1mL DMSO) $55 2021-12-16 Buy
ApexBio Technology A2587 PMSF 100g $270 2021-12-16 Buy
Apolloscientific PC6222M Phenylmethanesulphonylfluoride 99% 25g $50 2021-12-16 Buy
Apolloscientific BIP0329 Phenylmethanesulphonylfluoride 99% 25g $50 2021-12-16 Buy
Apolloscientific BIP0329 Phenylmethanesulphonylfluoride 99% 100g $148 2021-12-16 Buy
Apolloscientific PC6222M Phenylmethanesulphonylfluoride 99% 100g $148 2021-12-16 Buy
Apolloscientific PC6222M Phenylmethanesulphonylfluoride 99% 250g $327 2021-12-16 Buy
Apolloscientific BIP0329 Phenylmethanesulphonylfluoride 99% 250g $327 2021-12-16 Buy
Cayman Chemical 14333 Phenylmethylsulfonyl fluoride ≥98% 5g $32 2024-03-01 Buy

Properties

Melting point :92-95 °C
Boiling point :112 °C16 mm Hg(lit.)
Density :0.797 g/mL at 20 °C
Flash point :222 °F
storage temp. :2-8°C
solubility :dry solvents (ethanol, methanol, and 2-propanol): 200 mM Stock solution are stable for months at 4°C.
form :Needles (May Agglomerate)
color :White
Water Solubility :hydrolysis
Sensitive :Moisture Sensitive
Merck :14,7542
BRN :2088311
Stability :Moisture Sensitive
InChIKey :YBYRMVIVWMBXKQ-UHFFFAOYSA-N
CAS DataBase Reference :329-98-6(CAS DataBase Reference)
EPA Substance Registry System :Benzenemethanesulfonyl fluoride (329-98-6)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H301 Toxic if swalloed Acute toxicity,oral Category 3 Danger GHS hazard pictograms P264, P270, P301+P310, P321, P330,P405, P501
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger GHS hazard pictograms P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
Precautionary statements:
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

Phenylmethylsulfonyl fluoride (PMSF) is a nonspecific, irreversible inhibitor of serine proteases and other enzymes, including acetylcholinesterase, palmityl coenzyme A deacylase, arylsulfatase A, chymotrypsin, and trypsin. It is used in protein solublization studies in order to deactivate proteases from digesting proteins of interest after cell lysis. Because PMSF specifically sulfonylates the hydroxal groups of active site serine residues of enzymes, it can be used as a chemical label to identify essential active site serines in an enzyme. PMSF is known to alter the actions of anandamide by blocking its metabolism and can produce cannabinoid effects in mice, including antinociception, hypothermia, and immobility with ED50 values of 86, 224, and 206 mg/kg, respectively.

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