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ChemicalBook >> CAS DataBase List >> DL-2-AMINO-3-PHOSPHONOPROPIONIC ACID

DL-2-AMINO-3-PHOSPHONOPROPIONIC ACID

DL-2-AMINO-3-PHOSPHONOPROPIONIC ACID price.
  • $126 - $1092
  • Product name: DL-2-AMINO-3-PHOSPHONOPROPIONIC ACID
  • CAS: 20263-06-3
  • MF: C3H8NO5P
  • MW: 169.07
  • EINECS:
  • MDL Number:MFCD00014350
  • Synonyms:DL-2-AMINO-3-PHOSPHONOPROPANOIC ACID;DL-2-AMINO-3-PHOSPHONOPROPIONIC ACID;DL-AP3;AP-3;3-Phosphonoalanine.;D,L-2-Amino-3-phosphonopropionic acid, 98 %;3-Phosphono-DL-alanine, AP-3;rac-(2R*)-2-Amino-3-phosphonopropionic acid
6 prices
Selected condition：
Brand
  • AK Scientific
  • American Custom Chemicals Corporation
  • ApexBio Technology
  • Sigma-Aldrich
  • Tocris
  • Usbiological
Package
  • 100
  • 100MG
  • 1g
  • ManufacturerAK Scientific
  • Product number5159BA
  • Product descriptionD-2-Amino-3-phosphono-propionicacid
  • Packaging1g
  • Price$1092
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberING0006601
  • Product descriptionD,L-2-AMINO-3-PHOSPHONOPROPIONIC ACID 95.00%
  • Packaging100MG
  • Price$641.55
  • Updated2021-12-16
  • Buy
  • ManufacturerApexBio Technology
  • Product numberA4535
  • Product descriptionDL-AP3
  • Packaging100mg
  • Price$147
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberA4910
  • Product descriptionDL-2-Amino-3-phosphonopropionic acid
  • Packaging100mg
  • Price$133
  • Updated2024-03-01
  • Buy
  • ManufacturerTocris
  • Product number0125
  • Product descriptionDL-AP3
  • Packaging100
  • Price$126
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number255157
  • Product descriptionDL-AP3
  • Packaging100mg
  • Price$366
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 5159BA D-2-Amino-3-phosphono-propionicacid 1g $1092 2021-12-16 Buy
American Custom Chemicals Corporation ING0006601 D,L-2-AMINO-3-PHOSPHONOPROPIONIC ACID 95.00% 100MG $641.55 2021-12-16 Buy
ApexBio Technology A4535 DL-AP3 100mg $147 2021-12-16 Buy
Sigma-Aldrich A4910 DL-2-Amino-3-phosphonopropionic acid 100mg $133 2024-03-01 Buy
Tocris 0125 DL-AP3 100 $126 2021-12-16 Buy
Usbiological 255157 DL-AP3 100mg $366 2021-12-16 Buy

Properties

Melting point :227-229 °C(lit.)
storage temp. :0-6°C
solubility :Water (Slightly, Heated)
form :solid
color :Light Brown
CAS DataBase Reference :20263-06-3(CAS DataBase Reference)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

DL-2-Amino-3-phosphonopropionic acid (DL-AP3), a racemic preparation of D-AP3 and L-AP3, is an inhibitor of phosphoserine phosphatase and an antagonist of the receptor mGluR( metabotropic glutamate receptor), blocking phosphoinositide turnover mediated by the mGluR. D-AP3 demonstrates more potent inhibition of phosphoserine phosphatase than L-AP3, and D-AP3 is specifically active at phosphoserine phosphatase while L-AP3 produces mGluR antagonism with similar potency to its inhibition of phosphoserine phosphatase. L-AP3 is described to antagonize the metabotropic Ca2+ mobilizing effects of the mGluR agonist Trans-ACPD (sc-202367) while D-AP3 shows no such antagonism.

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