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ChemicalBook >> CAS DataBase List >> Methyl 4-Fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate

Methyl 4-Fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate

Methyl 4-Fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate price.
  • $66 - $1973
  • Product name: Methyl 4-Fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate
  • CAS: 1235865-75-4
  • MF: C15H11FN2O3
  • MW: 286.26
  • EINECS:-0
  • MDL Number:MFCD28129691
  • Synonyms:abt199 int 2;ABT199 intermediate 3;ABT199 intermediates;Methyl 2-((1H-pyrrolo[2,3-b]pyrin- 5-yl)oxy)-4-fluorobenzoate;ABT-199 Intermediate;methyl 4-fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate;Methyl-2-((1H-pyrrolo[2,3-b]pyridine-5-yl)oxy)-4-fluorobenzoate;Venetoclax Intermediate 3
16 prices
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Brand
  • AK Scientific
  • Alichem
  • Ambeed
  • Chemenu
  • Crysdot
  • TRC
Package
  • 250mg
  • 500mg
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  • 5g
  • 10g
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  • 100g
  • ManufacturerAK Scientific
  • Product numberJ55660
  • Product descriptionMethyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate
  • Packaging10g
  • Price$238
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ55660
  • Product descriptionMethyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate
  • Packaging50g
  • Price$794
  • Updated2021-12-16
  • Buy
  • ManufacturerAK Scientific
  • Product numberJ55660
  • Product descriptionMethyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate
  • Packaging100g
  • Price$1430
  • Updated2021-12-16
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  • ManufacturerAlichem
  • Product number1235865754
  • Product descriptionMethyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate
  • Packaging10g
  • Price$612
  • Updated2021-12-16
  • Buy
  • ManufacturerAlichem
  • Product number1235865754
  • Product descriptionMethyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate
  • Packaging25g
  • Price$1188
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA214829
  • Product descriptionMethyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate 98+%
  • Packaging1g
  • Price$66
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA214829
  • Product descriptionMethyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate 98+%
  • Packaging5g
  • Price$145
  • Updated2021-12-16
  • Buy
  • ManufacturerAmbeed
  • Product numberA214829
  • Product descriptionMethyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate 98+%
  • Packaging25g
  • Price$404
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM105037
  • Product descriptionmethyl4-fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate 95%+
  • Packaging250mg
  • Price$72
  • Updated2021-12-16
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  • ManufacturerChemenu
  • Product numberCM105037
  • Product descriptionmethyl4-fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate 95%+
  • Packaging1g
  • Price$150
  • Updated2021-12-16
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  • ManufacturerChemenu
  • Product numberCM105037
  • Product descriptionmethyl4-fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate 95%+
  • Packaging5g
  • Price$690
  • Updated2021-12-16
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  • ManufacturerChemenu
  • Product numberCM105037
  • Product descriptionmethyl4-fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate 95%+
  • Packaging10g
  • Price$988
  • Updated2021-12-16
  • Buy
  • ManufacturerChemenu
  • Product numberCM105037
  • Product descriptionmethyl4-fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate 95%+
  • Packaging25g
  • Price$1973
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11319661
  • Product descriptionMethyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate 95+%
  • Packaging5g
  • Price$286
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD11319661
  • Product descriptionMethyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate 95+%
  • Packaging10g
  • Price$478
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberM265625
  • Product descriptionMethyl4-Fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate
  • Packaging500mg
  • Price$165
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific J55660 Methyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate 10g $238 2021-12-16 Buy
AK Scientific J55660 Methyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate 50g $794 2021-12-16 Buy
AK Scientific J55660 Methyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate 100g $1430 2021-12-16 Buy
Alichem 1235865754 Methyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate 10g $612 2021-12-16 Buy
Alichem 1235865754 Methyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate 25g $1188 2021-12-16 Buy
Ambeed A214829 Methyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate 98+% 1g $66 2021-12-16 Buy
Ambeed A214829 Methyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate 98+% 5g $145 2021-12-16 Buy
Ambeed A214829 Methyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate 98+% 25g $404 2021-12-16 Buy
Chemenu CM105037 methyl4-fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate 95%+ 250mg $72 2021-12-16 Buy
Chemenu CM105037 methyl4-fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate 95%+ 1g $150 2021-12-16 Buy
Chemenu CM105037 methyl4-fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate 95%+ 5g $690 2021-12-16 Buy
Chemenu CM105037 methyl4-fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate 95%+ 10g $988 2021-12-16 Buy
Chemenu CM105037 methyl4-fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate 95%+ 25g $1973 2021-12-16 Buy
Crysdot CD11319661 Methyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate 95+% 5g $286 2021-12-16 Buy
Crysdot CD11319661 Methyl2-((1H-pyrrolo[2,3-b]pyridin-5-yl)oxy)-4-fluorobenzoate 95+% 10g $478 2021-12-16 Buy
TRC M265625 Methyl4-Fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate 500mg $165 2021-12-16 Buy

Properties

Density :1.377±0.06 g/cm3(Predicted)
storage temp. :Sealed in dry,Room Temperature
pka :13.21±0.40(Predicted)
CAS DataBase Reference :1235865-75-4

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H318 Causes serious eye damage Serious eye damage/eye irritation Category 1 Danger GHS hazard pictograms P280, P305+P351+P338, P310
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P270 Do not eat, drink or smoke when using this product.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310 Immediately call a POISON CENTER or doctor/physician.
P321 Specific treatment (see … on this label).
P330 Rinse mouth.
P332+P313 IF SKIN irritation occurs: Get medical advice/attention.
P362 Take off contaminated clothing and wash before reuse.
P501 Dispose of contents/container to..…

Description

Methyl 4-Fluoro-2-{1H-pyrrolo[2,3-b]pyridin-5-yloxy}benzoate is the intermediate for ABT 199 (A112430), which is a potent and selective BCL-2 inhibitor that achieves potent antitumor activity while sparing platelets. It’s practical application is to treat chronic lymphocytic leukaemic cells and estrogen receptor-positive breast cancer.