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ChemicalBook >> CAS DataBase List >> 10,10-BIS(4-PYRIDINYLMETHYL)-9(10H)-ANTHRACENONE DIHYDROCHLORIDE

10,10-BIS(4-PYRIDINYLMETHYL)-9(10H)-ANTHRACENONE DIHYDROCHLORIDE

10,10-BIS(4-PYRIDINYLMETHYL)-9(10H)-ANTHRACENONE DIHYDROCHLORIDE price.
  • $174 - $1199.42
  • Product name: 10,10-BIS(4-PYRIDINYLMETHYL)-9(10H)-ANTHRACENONE DIHYDROCHLORIDE
  • CAS: 122955-42-4
  • MF: C26H20N2O
  • MW: 376.45
  • EINECS:
  • MDL Number:MFCD05662331
  • Synonyms:10,10-BIS(4-PYRIDINYLMETHYL)-9(10H)-ANTHRACENONE DIHYDROCHLORIDE;XE9912HCl;XE 991;XE 991 DIHYDROCHLORIDE;10-bis(4-Pyridinylmethyl)-9(10H)-anthracenone dihydrochloride;9(10H)-Anthracenone, 10,10-bis(4-pyridinylmethyl)-;10,10-Bis(pyridin-4-ylmethyl)anthracen-9(10H)-one
8 prices
Selected condition：
Brand
  • American Custom Chemicals Corporation
  • Sigma-Aldrich
  • Tocris
  • TRC
  • Usbiological
Package
  • 50
  • 10MG
  • 10
  • 5mg
  • 50MG
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0004436
  • Product descriptionXE-991 95.00%
  • Packaging10MG
  • Price$238.35
  • Updated2021-12-16
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberINB0004436
  • Product descriptionXE-991 95.00%
  • Packaging50MG
  • Price$1199.42
  • Updated2021-12-16
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberX2254
  • Product descriptionXE-991 ≥98% (HPLC)
  • Packaging10mg
  • Price$174
  • Updated2024-03-01
  • Buy
  • ManufacturerSigma-Aldrich
  • Product numberX2254
  • Product descriptionXE-991 ≥98% (HPLC)
  • Packaging50mg
  • Price$738
  • Updated2024-03-01
  • Buy
  • ManufacturerTocris
  • Product number2000
  • Product descriptionXE991dihydrochloride ≥99%(HPLC)
  • Packaging10
  • Price$187
  • Updated2021-12-16
  • Buy
  • ManufacturerTocris
  • Product number2000
  • Product descriptionXE991dihydrochloride ≥99%(HPLC)
  • Packaging50
  • Price$780
  • Updated2021-12-16
  • Buy
  • ManufacturerTRC
  • Product numberX750953
  • Product descriptionXE991
  • Packaging5mg
  • Price$220
  • Updated2021-12-16
  • Buy
  • ManufacturerUsbiological
  • Product number257129
  • Product descriptionXE 991 dihydrochloride
  • Packaging10mg
  • Price$446
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
American Custom Chemicals Corporation INB0004436 XE-991 95.00% 10MG $238.35 2021-12-16 Buy
American Custom Chemicals Corporation INB0004436 XE-991 95.00% 50MG $1199.42 2021-12-16 Buy
Sigma-Aldrich X2254 XE-991 ≥98% (HPLC) 10mg $174 2024-03-01 Buy
Sigma-Aldrich X2254 XE-991 ≥98% (HPLC) 50mg $738 2024-03-01 Buy
Tocris 2000 XE991dihydrochloride ≥99%(HPLC) 10 $187 2021-12-16 Buy
Tocris 2000 XE991dihydrochloride ≥99%(HPLC) 50 $780 2021-12-16 Buy
TRC X750953 XE991 5mg $220 2021-12-16 Buy
Usbiological 257129 XE 991 dihydrochloride 10mg $446 2021-12-16 Buy

Properties

Melting point :231-232 °C
Boiling point :585.0±38.0 °C(Predicted)
Density :1.238±0.06 g/cm3(Predicted)
storage temp. :2-8°C
solubility :DMSO: >20mg/mL
form :solid
pka :6.08±0.10(Predicted)
color :white to beige
Water Solubility :Soluble in water (100mM)

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P271 Use only outdoors or in a well-ventilated area.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

XE 991 dihydrochloride is a potent and selective blocker of KCNQ voltage-gated potassium channels. Blocks KCNQ2+3/M-currents (IC50 = 0.6-0.98 μM) and KCNQ1 homomeric channels (IC50 = 0.75 μM) but is less potent against KCNQ1/minK channels (IC50 = 11.1 μM).

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