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ChemicalBook >> CAS DataBase List >> N,O-Bis(trimethylsilyl)acetamide

N,O-Bis(trimethylsilyl)acetamide

N,O-Bis(trimethylsilyl)acetamide price.
  • $18 - $3404.8
  • Product name: N,O-Bis(trimethylsilyl)acetamide
  • CAS: 10416-59-8
  • MF: C8H21NOSi2
  • MW: 203.43
  • EINECS:233-892-7
  • MDL Number:MFCD00008270
  • Synonyms:n-(trimethylsilyl)-acetimidicacitrimethylsilylester ;n-(trimethylsilyl)-ethanimidicacitrimethylsilylester ;Trimethylsilyl N-trimethylsilylacetamidate;NO-Bis (trimethylsilyl) acetamide 90+ % gas chromatography;N,O-Bis(trimethylsilyl)acetamide Kit TMS-BA (25% in Acetonitrile) 1 ml * 8 / Reaction vial, capacity 2 ml * 8;Trimethylsilyl (1E)-N-[(E)-trimethylsilyl]ethanimidoate;Acetimidic acid, N-(trimethylsilyl)-, trimethylsilyl ester;CB2500
46 prices
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Brand
  • AK Scientific
  • Alfa Aesar
  • American Custom Chemicals Corporation
  • Apolloscientific
  • Biosynth Carbosynth
  • Chem-Impex
  • Frontier Specialty Chemicals
  • Matrix Scientific
  • Medical Isotopes, Inc.
  • Oakwood
  • Sigma-Aldrich
  • SynQuest Laboratories
  • TCI Chemical
  • TRC
Package
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  • 1kit
  • ManufacturerAK Scientific
  • Product numberX7204
  • Product descriptionN,O-Bis(trimethylsilyl)acetamide
  • Packaging100g
  • Price$126
  • Updated2021-12-16
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberL00183
  • Product descriptionN,O-Bis(trimethylsilyl)acetamide, 95%
  • Packaging25g
  • Price$43.5
  • Updated2024-03-01
  • Buy
  • ManufacturerAlfa Aesar
  • Product numberL00183
  • Product descriptionN,O-Bis(trimethylsilyl)acetamide, 95%
  • Packaging100g
  • Price$108
  • Updated2024-03-01
  • Buy
  • ManufacturerAmerican Custom Chemicals Corporation
  • Product numberORS0004978
  • Product descriptionN,O-BIS(TRIMETHYLSILYL)ACETAMIDE 95.00%
  • Packaging100G
  • Price$2333.1
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberOR5155A
  • Product descriptionTrimethylsilyl N-(trimethylsilyl)acetimidate
  • Packaging100g
  • Price$21
  • Updated2021-12-16
  • Buy
  • ManufacturerApolloscientific
  • Product numberOR5155A
  • Product descriptionTrimethylsilyl N-(trimethylsilyl)acetimidate
  • Packaging500g
  • Price$57
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB03098
  • Product descriptionN,O-Bis(trimethylsilyl) acetamide
  • Packaging100g
  • Price$55
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB03098
  • Product descriptionN,O-Bis(trimethylsilyl) acetamide
  • Packaging250g
  • Price$95
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB03098
  • Product descriptionN,O-Bis(trimethylsilyl) acetamide
  • Packaging500g
  • Price$130
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB03098
  • Product descriptionN,O-Bis(trimethylsilyl) acetamide
  • Packaging1kg
  • Price$200
  • Updated2021-12-16
  • Buy
  • ManufacturerBiosynth Carbosynth
  • Product numberFB03098
  • Product descriptionN,O-Bis(trimethylsilyl) acetamide
  • Packaging2Kg
  • Price$380
  • Updated2021-12-16
  • Buy
  • ManufacturerChem-Impex
  • Product number30800
  • Product descriptionN,O-Bis(trimethylsilyl)acetamide,≥98%(GC)Hazmat ≥98%(GC)
  • Packaging25G
  • Price$27.66
  • Updated2021-12-16
  • Buy
  • ManufacturerChem-Impex
  • Product number30800
  • Product descriptionN,O-Bis(trimethylsilyl)acetamide,98%(GC) 98%(GC)
  • Packaging100G
  • Price$53.2
  • Updated2021-12-16
  • Buy
  • ManufacturerChem-Impex
  • Product number30800
  • Product descriptionN,O-Bis(trimethylsilyl)acetamide,98%(GC) 98%(GC)
  • Packaging250G
  • Price$95.76
  • Updated2021-12-16
  • Buy
  • ManufacturerChem-Impex
  • Product number30800
  • Product descriptionN,O-Bis(trimethylsilyl)acetamide,≥98%(GC)Hazmat ≥98%(GC)
  • Packaging1KG
  • Price$376.23
  • Updated2021-12-16
  • Buy
  • ManufacturerChem-Impex
  • Product number30800
  • Product descriptionN,O-Bis(trimethylsilyl)acetamide,98%(GC) 98%(GC)
  • Packaging5KG
  • Price$1787.52
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific X7204 N,O-Bis(trimethylsilyl)acetamide 100g $126 2021-12-16 Buy
Alfa Aesar L00183 N,O-Bis(trimethylsilyl)acetamide, 95% 25g $43.5 2024-03-01 Buy
Alfa Aesar L00183 N,O-Bis(trimethylsilyl)acetamide, 95% 100g $108 2024-03-01 Buy
American Custom Chemicals Corporation ORS0004978 N,O-BIS(TRIMETHYLSILYL)ACETAMIDE 95.00% 100G $2333.1 2021-12-16 Buy
Apolloscientific OR5155A Trimethylsilyl N-(trimethylsilyl)acetimidate 100g $21 2021-12-16 Buy
Apolloscientific OR5155A Trimethylsilyl N-(trimethylsilyl)acetimidate 500g $57 2021-12-16 Buy
Biosynth Carbosynth FB03098 N,O-Bis(trimethylsilyl) acetamide 100g $55 2021-12-16 Buy
Biosynth Carbosynth FB03098 N,O-Bis(trimethylsilyl) acetamide 250g $95 2021-12-16 Buy
Biosynth Carbosynth FB03098 N,O-Bis(trimethylsilyl) acetamide 500g $130 2021-12-16 Buy
Biosynth Carbosynth FB03098 N,O-Bis(trimethylsilyl) acetamide 1kg $200 2021-12-16 Buy
Biosynth Carbosynth FB03098 N,O-Bis(trimethylsilyl) acetamide 2Kg $380 2021-12-16 Buy
Chem-Impex 30800 N,O-Bis(trimethylsilyl)acetamide,≥98%(GC)Hazmat ≥98%(GC) 25G $27.66 2021-12-16 Buy
Chem-Impex 30800 N,O-Bis(trimethylsilyl)acetamide,98%(GC) 98%(GC) 100G $53.2 2021-12-16 Buy
Chem-Impex 30800 N,O-Bis(trimethylsilyl)acetamide,98%(GC) 98%(GC) 250G $95.76 2021-12-16 Buy
Chem-Impex 30800 N,O-Bis(trimethylsilyl)acetamide,≥98%(GC)Hazmat ≥98%(GC) 1KG $376.23 2021-12-16 Buy
Chem-Impex 30800 N,O-Bis(trimethylsilyl)acetamide,98%(GC) 98%(GC) 5KG $1787.52 2021-12-16 Buy

Properties

Melting point :24 °C
Boiling point :71-73 °C35 mm Hg(lit.)
Density :0.832 g/mL at 20 °C(lit.)
vapor pressure :10 hPa (50 °C)
refractive index :n20/D 1.417(lit.)
Flash point :53 °F
storage temp. :Store below +30°C.
solubility :Miscible with many nonpolar and polar aprotic solvents.
pka :5.82±0.50(Predicted)
form :Crystalline Powder, Crystals and/or Chunks
Specific Gravity :0.832
color :Light yellow or beige to brown
Sensitive :Moisture Sensitive
Hydrolytic Sensitivity :7: reacts slowly with moisture/water
BRN :1306669
CAS DataBase Reference :10416-59-8(CAS DataBase Reference)
NIST Chemistry Reference :Ethanimidic acid, N-(trimethylsilyl)-, trimethylsilyl ester(10416-59-8)
EPA Substance Registry System :Ethanimidic acid, N-(trimethylsilyl)-, trimethylsilyl ester (10416-59-8)

Safety Information

Symbol(GHS): GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H226 Flammable liquid and vapour Flammable liquids Category 3 Warning
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H314 Causes severe skin burns and eye damage Skin corrosion/irritation Category 1A, B, C Danger GHS hazard pictograms P260,P264, P280, P301+P330+ P331,P303+P361+P353, P363, P304+P340,P310, P321, P305+ P351+P338, P405,P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233 Keep container tightly closed.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P303+P361+P353 IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

N,O-Bis(trimethylsilyl)acetamide is used as a regioselective desulfation reagent as well as a preparatory agent for carbohydrate and alcohol trimethylsilyl ethers. It is also used for the derivatization of polar functional groups such as carboxylic acids, phenols, steroids, amines, alcohols, alkaloids and amides. It is employed in the formation of stable trimethylsilyl derivatives. Further, it is used in analytical chemistry for the derivatization of compounds in analysis to increase their volatility and to introduce the trimethylsilyl protecting group in organic synthesis. In addition to this, it is used in the protection of hydroxyl groups in natural products, functional groups in organic intermediates and derivatization reagent for gas chromatography-Mass spectral analysis of phenolic acids in fruits.

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