Ro 01-6128 Chemische Eigenschaften,Einsatz,Produktion Methoden

Beschreibung

Glutamate, the major excitatory neurotransmitter in the CNS, activates eight known subtypes of metabotropic glutamate receptors (mGluRs). Highly selective modulators designed to act at allosteric sites on certain mGluR subtypes are being developed to preferentially regulate subtype-specific, glutamate-induced receptor activation. Ro 01-6128 is a positive allosteric modulator of mGluR1 that can potentiate glutamate-induced calcium release at rat mGluR1a with an EC₅₀ value of 104 nM. Ro 01-6128 activates ERK1/2 phosphorylation in the absence of exogenously added glutamate with an EC₅₀ value of 248 nM and potentiates glutamate-induced cAMP production with an EC₅₀ value of 21.5 μM.

Verwenden

Ro 01-6128 is an allosteric mGluR-1 activator.

Ro 01-6128 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Ro 01-6128 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Firmenname	Telefon	E-Mail	Land	Produktkatalog	Edge Rate
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32161	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52924	58
TargetMol Chemicals Inc.	+8613564774135	zijue.cai@tsbiochem.com	United States	19885	58
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8447	60
MQ (shanghai) Pharmaceuticals Co., Ltd.	13761635123	1014988033@qq.com	China	4997	55
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	order@med-bio.cn	China	8140	58
JinOu Biomedical (Nanjing) Co., Ltd.	13000000000	jinoupharma@163.com	China	11721	58
TargetMol Chemicals Inc.	4008200310	marketing@tsbiochem.com	China	24644	58
Nanjing Tengyi Biotechnology Co., Ltd	025-58851786 17714337195	sales@tybiochem.com	China	6813	58
Shanghai Yifei Biotechnology Co. , Ltd.	021-65675885 18964387627	customer_service@efebio.com	China	11974	58

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• Ro 01-6128
• ILSZPWZFQHSKLW-UHFFFAOYSA-N
• (Diphenylacetyl)-carbamic acid ethy ester
• ethyl N-[2,2-di(phenyl)acetyl]carbamate
• Ro 01 6128,Ro 016128
• Carbamic acid, N-(2,2-diphenylacetyl)-, ethyl ester
• Ethyl (2,2-diphenylacetyl)carbamate
• 302841-86-7