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SEN 12333

SEN 12333 Struktur
874450-44-9
CAS-Nr.
874450-44-9
Englisch Name:
SEN 12333
Synonyma:
SEN 12333;WAY 317538;SEN 12333 WAY-317538;N-[4-(3-Pyridinyl)phenyl]-4-MorpholinepentanaMide;5-Morpholino-N-(4-(pyridin-3-yl)phenyl)pentanamide;4-MorpholinepentanaMide, N-[4-(3-pyridinyl)phenyl]-;Neuroprotective,nAChR,Inhibitor,SEN-12333,WAY317538,SEN12333,Alzheimer's Disease,inhibit,WAY 317538,Nicotinic acetylcholine receptors,schizophrenia,WAY-317538
CBNumber:
CB72603004
Summenformel:
C20H25N3O2
Molgewicht:
339.43
MOL-Datei:
874450-44-9.mol

SEN 12333 Eigenschaften

storage temp. 
Store at RT
L?slichkeit
Soluble to 100 mM in DMSO
Aggregatzustand
Powder
Farbe
White to light yellow

Sicherheit

SEN 12333 Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

SEN 12333 is a nicotinic acetylcholine receptor (nAChR) agonist. SEN 12333 displays functional antagonism at histamine H3 receptors (IC50 = 103 nM) and weak agonist activity at human ganglionic α3 nAChRs (IC50 = 8.5 μM). Neuroprotective in a rodent model of quisqualic acid-induced cholinergic degeneration. SEN 12333 is a brain penetrant and orally bioavailable.

SEN 12333 Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


SEN 12333 Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

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  • SEN 12333
  • 4-MorpholinepentanaMide, N-[4-(3-pyridinyl)phenyl]-
  • N-[4-(3-Pyridinyl)phenyl]-4-MorpholinepentanaMide
  • WAY 317538
  • SEN 12333 WAY-317538
  • 5-Morpholino-N-(4-(pyridin-3-yl)phenyl)pentanamide
  • Neuroprotective,nAChR,Inhibitor,SEN-12333,WAY317538,SEN12333,Alzheimer's Disease,inhibit,WAY 317538,Nicotinic acetylcholine receptors,schizophrenia,WAY-317538
  • 874450-44-9
  • Amines
  • Heterocycles
  • Intermediates & Fine Chemicals
  • Pharmaceuticals
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