モキシフロキサシン塩酸塩
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- CAS番號.
- 186826-86-8
- 化學(xué)名:
- モキシフロキサシン塩酸塩
- 別名:
- モキシフロキサシン塩酸塩;モキシフロキサシン 塩酸塩;塩酸モキシフロキサシン;モキシフロキサシン塩酸塩 (JAN);1-シクロプロピル-6-フルオロ-8-メトキシ-7-[(4aS,7aS)-オクタヒドロ-1H-ピロロ[3,4-b]ピリジン-6-イル]-4-オキソ-1,4-ジヒドロキノリン-3-カルボン酸?塩酸塩;1-シクロプロピル-7-[(1S,6S)-2,8-ジアザビシクロ[4.3.0]ノナン-8-イル]-6-フルオロ-8-メトキシ-4-オキソ-1,4-ジヒドロキノリン-3-カルボン酸?塩酸塩;1,4-ジヒドロ-1-シクロプロピル-6-フルオロ-8-メトキシ-4-オキソ-7-[[(4aα,7aα)-オクタヒドロ-1H-ピロロ[3,4-b]ピリジン]-6-イル]キノリン-3-カルボン酸?塩酸塩;ベガモックス;モキシフロキサシン?塩酸塩;アベロックス;1-シクロプロピル-6-フルオロ-8-メトキシ-7-[(4aS,7aS)-オクタヒドロピロロ[3,4-b]ピリジン-6-イル]-4-オキソ-1,4-ジヒドロキノリン-3-カルボン酸=一塩酸塩
- 英語名:
- Moxifloxacin hydrochloride
- 英語別名:
- MOXIFLOXACIN HCL;Avelox;AVALOX;Moxifloxacin hydrochloride CRS;1-cyclopropyl-6-fluoro-8-methoxy-7-((4aS,7aS)-octahydropyrrolo[3,4-b]pyridin-6-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride;ACTIRA;Actura;MoxifL;PROFLOX;BAY-12-8039
- CBNumber:
- CB3191433
- 化學(xué)式:
- C21H25ClFN3O4
- 分子量:
- 437.8923032
- MOL File:
- 186826-86-8.mol
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モキシフロキサシン塩酸塩 物理性質(zhì)
- 融點(diǎn) :
- Slightly yellow to yellow crystalline powder, mp 324-325°
- 比旋光度 :
- 25D -256° (c = 0.5 in water)
- 沸點(diǎn) :
- 636℃
- RTECS 番號:
- VB1983750
- 閃點(diǎn) :
- >110°(230°F)
- 貯蔵溫度 :
- 2-8°C
- 溶解性:
- H2O: 可溶5mg/mL、透明 (加溫)
- 外見 :
- 粉
- 色:
- 白からベージュ
- 水溶解度 :
- 水にやや溶けにくい。 DMSOに可溶
- BRN :
- 8377447
- InChIKey:
- IDIIJJHBXUESQI-DFIJPDEKSA-N
- SMILES:
- N1(C2CC2)C2=C(C=C(F)C(N3C[C@]4([H])CCCN[C@]4([H])C3)=C2OC)C(=O)C(C(O)=O)=C1.[H]Cl |&1:12,18,r|
- CAS データベース:
- 186826-86-8(CAS DataBase Reference)
モキシフロキサシン塩酸塩 価格
もっと(15)
| メーカー |
製品番號 |
製品説明 |
CAS番號 |
包裝 |
価格 |
更新時(shí)間 |
購入 |
|
富士フイルム和光純薬株式會社(wako)
|
W01LKTM5794 |
モキシフロキサシン塩酸塩
Moxifloxacin Hydrochloride |
186826-86-8 |
100mg |
￥42000 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式會社(wako)
|
W01LKTM5794 |
モキシフロキサシン塩酸塩
Moxifloxacin Hydrochloride |
186826-86-8 |
500mg |
￥161100 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式會社(wako)
|
45796-1A |
Moxifloxacin hydrochloride |
186826-86-8 |
1g |
￥39270 |
2024-07-01 |
購入 |
|
Sigma-Aldrich Japan
|
Y0000703 |
モキシフロキサシン 塩酸塩 European Pharmacopoeia (EP) Reference Standard
Moxifloxacin hydrochloride European Pharmacopoeia (EP) Reference Standard |
186826-86-8 |
y0000703 |
￥24800 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
32477 |
モキシフロキサシン 塩酸塩 VETRANAL?, analytical standard
Moxifloxacin hydrochloride VETRANAL?, analytical standard |
186826-86-8 |
50mg |
￥51400 |
2024-03-01 |
購入 |
モキシフロキサシン塩酸塩 化學(xué)特性,用途語,生産方法
効能
抗菌薬, 核酸合成阻害薬
商品名
アベロックス (バイエル薬品); ベガモックス (ノバルティスファーマ)
説明
Moxifioxacin hydrochlodde is one of the two new fluoroquinolonecarboxylic
acid antibiotics introduced in 1999 for the treatment of
respiratory tract infections such as community-acquired pneumonia, acute
exacerbations of bronchitis or acute sinusitis. Moxifloxacin can be synthesized
through a 12 step sequence from the classical 4-quinolone-3-carboxylic acid
template. Some advantages of Moxifloxacin over Ciprofloxacin, another of
Bayer's launched quinolones, have been shown, i.e. an enhanced activity
against Gram-positive bacteria (Streptococcus pneumoniae, Clostndium
pneumoniae), a favorable pharmacokinetic profile (good tissue penetration and
plasma concentrations above MICs) and a lack of phototoxicity (UVA
irradiation).
化學(xué)的特性
Light yellow to yellow crystalline powder
使用
Moxifloxacin Hydrochloride is an antibacterial agent that inhibits the activities of Topo II (DNA gyrase) and topoisomerase IV.
定義
ChEBI: Moxifloxacin hydrochloride is a hydrochloride comprising equimolar amounts of moxifloxacin and hydrogen chloride. It has a role as an antibacterial drug. It contains a moxifloxacinium(1+).
一般的な説明
Moxifloxacin Hydrochloride is an anti-infectious compound that belongs to the class of fluoroquinolone antibiotics. It is a well-known broad-spectrum antibiotic prescription medicine effective against a variety of Gram-positive and Gram-negative bacteria including the anaerobic type. It is an
S,S-isomer with two chiral centers. It works by preventing the activity of various crucial enzymes involved in the replication, transcription, recombination, and repair of deoxyribonucleic acid in the bacteria such as DNA gyrase (topoisomerase II), topoisomerase IV. It finds its application in the treatment of various ocular and respiratory tract infections.
モキシフロキサシン塩酸塩 上流と下流の製品情報(bào)
原材料
準(zhǔn)備製品
モキシフロキサシン塩酸塩 生産企業(yè)
Global( 783)Suppliers
モキシフロキサシン塩酸塩 スペクトルデータ(1HNMR)
186826-86-8(モキシフロキサシン塩酸塩)キーワード:
- 186826-86-8
- BAY-12-8039
- BAY12-8039 HCl
- Moxifloxacin hydrochloride, >=99%
- 4-dihydroquinoline-3-carboxylic acid hydrochloride
- Moxifloxacin Hydrochloride 1
- (1's,6's)-1-cyclopropyl-7-(2,8-diazabicyclo[4.3.0]non-8-yl)-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride
- Moxifloxacin Hydrochloride Tablets
- Moxifloxacin hydrochlorideUSP,
98.0-102.0% (HPLC)
- Actura
- ACTIRA
- PROFLOX
- MOXIFLOXACIN HYDROCHLORIDE
- 1-CYCLOPROPYL-6-FLUORO-1,4-DIHYDRO- 8-METHOXY-7- [(4AS,7AS)-OCTAHYDRO-6H-PYRROLO[3,4-B]PYRIDIN-6-YL]-4-OXO-3-QUINOLINECARBOXYLIC ACID HYDROCHLORIDE
- 1-CYCLOPROPYL-7-[(S,S)-2,8-DIAZA-BICYCLO[4.3.0]NON-8-YL]-6-FLUORO-8-METHOXY-1,4-DIHYDRO-4-OXO-3-QUINOLINE CARBOXYLIC ACID HYDROCHLORIDE
- MoxifloxacineHCl
- Moxifloxacinehydrochloride
- 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7- [(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-,monohydrochloride
- Moxiflaxacin HCL
- Moxifloxacin Hydrochloride (200 mg)
- 1-Cyclopropyl-6-fluoro-7-((4aS,7aS)-hexahydro-1H-pyrrolo[3,4-b]pyridin-6(2H)-yl)-8-Methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride
- 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-Methoxy-7-(octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl)-4-oxo-, Monohydrochloride, (4aS-cis)-
- 1-Cyclopropyl-6-fluoro-8-Methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride
- Moxifloxacin HCl USP
- Moxifloxacin HCl (Monohydrate)
- Moxifloxacin and intermediates
- Moxifloxacin hydrochloride Solution, 1000ppm
- AVELOX; AVALOX
- 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-3-quinolinecarboxylic acid hydrochloride (1:1)
- Moxifloxacin Hydrochlorideand
- MoxifL
- モキシフロキサシン塩酸塩
- モキシフロキサシン 塩酸塩
- 塩酸モキシフロキサシン
- モキシフロキサシン塩酸塩 (JAN)
- 1-シクロプロピル-6-フルオロ-8-メトキシ-7-[(4aS,7aS)-オクタヒドロ-1H-ピロロ[3,4-b]ピリジン-6-イル]-4-オキソ-1,4-ジヒドロキノリン-3-カルボン酸?塩酸塩
- 1-シクロプロピル-7-[(1S,6S)-2,8-ジアザビシクロ[4.3.0]ノナン-8-イル]-6-フルオロ-8-メトキシ-4-オキソ-1,4-ジヒドロキノリン-3-カルボン酸?塩酸塩
- 1,4-ジヒドロ-1-シクロプロピル-6-フルオロ-8-メトキシ-4-オキソ-7-[[(4aα,7aα)-オクタヒドロ-1H-ピロロ[3,4-b]ピリジン]-6-イル]キノリン-3-カルボン酸?塩酸塩
- ベガモックス
- モキシフロキサシン?塩酸塩
- アベロックス
- 1-シクロプロピル-6-フルオロ-8-メトキシ-7-[(4aS,7aS)-オクタヒドロピロロ[3,4-b]ピリジン-6-イル]-4-オキソ-1,4-ジヒドロキノリン-3-カルボン酸=一塩酸塩