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Sitagliptin Impurity 12

化學(xué)構(gòu)造式
1803026-54-1
CAS番號.
1803026-54-1
化學(xué)名:
別名:
英語名:
Sitagliptin Impurity 12
英語別名:
Sitagliptin EP Impurity 12;(Z)-1-(3-(trifluoromethyl);(2Z)-1-[5,6-Dihydro-3-(trifluoromethyl)-1;(2Z)-1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-α]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-2-buten-1-one;2-Buten-1-one, 1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-, (2Z)-;(Z)-1-(3-(Trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)but-2-en-1-one (Sitagliptin Impurity)
CBNumber:
CB24842022
化學(xué)式:
C16H12F6N4O
分子量:
390.28
MOL File:
1803026-54-1.mol

Sitagliptin Impurity 12 物理性質(zhì)

沸點 :
517.5±60.0 °C(Predicted)
比重(密度) :
1.52±0.1 g/cm3(Predicted)
溶解性:
soluble in Chloroform, DCM, Methanol
酸解離定數(shù)(Pka):
-0.06±0.20(Predicted)
外見 :
Oil
色:
Light Yellow

安全性情報

Sitagliptin Impurity 12 価格

メーカー 製品番號 製品説明 CAS番號 包裝 価格 更新時間 購入

Sitagliptin Impurity 12 化學(xué)特性,用途語,生産方法

使用

(2Z)-1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-2-buten-1-one is an intermediate in the synthesis of 3-Desamino-2,3-dehydro Sitagliptin (D281985),an impurity of Sitagliptin (S491000). Sitagliptin is a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes.

Sitagliptin Impurity 12 上流と下流の製品情報

原材料

準備製品

Sitagliptin Impurity 12 生産企業(yè)

Global( 11)Suppliers
名前 電話番號 電子メール 國籍 製品カタログ 優(yōu)位度
SHENZHEN PHYSTANDARD BIO-TECH CO.,LTD 0755-0755-0755-83725350 13380397412
 3001280422@qq.com China 10262 58
Energy Chemical 021-58432009 400-005-6266
 marketing@energy-chemical.com China 44918 58
Henan Kehong Biological Technology Co. LTD 0371-55969461； 0371-86658258 19139748274
 info@kehobio.com China 2572 58
Molcoo Chemicals Inc. 18576690171
 3001025734@qq.com China 9628 58
Shanghai YuZn Pharm. Technology Co.,Ltd. 15921286451; 15921286451
 2010681527@qq.com China 5123 58
Shanghai Zerui Biotechnology Co., Ltd. 021-54580889 18321124657
 731997554@qq.com China 10608 58
ShenZhen H&D Pharmaceutical Technology Co., LTD +86-13217415044 18672472998
 zhangweiyue@hdimpurity.com China 7817 58
Hubei Moco Chemical Co., Ltd. 18627753421; 18627756402
 3001051413@qq.com China 19375 58
Taizhou Chuanxu Pharmaceutical Technology Co., Ltd. 13000000000
 974144639@qq.com China 8366 58
Biosynth Biological Technology (Suzhou) Co Ltd 51288865780
 sales@biosynth.com China 233051 58

1803026-54-1()キーワード:

  • 1803026-54-1
  • (Z)-1-(3-(trifluoromethyl)
  • 2-Buten-1-one, 1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-, (2Z)-
  • Sitagliptin EP Impurity 12
  • (2Z)-1-[5,6-Dihydro-3-(trifluoromethyl)-1
  • (Z)-1-(3-(Trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)but-2-en-1-one (Sitagliptin Impurity)
  • (2Z)-1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-α]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-2-buten-1-one
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