Gastric mucin NEW
| Price | $42 |
| Package | 500mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2024-11-19 |
Product Details
| Product Name: Gastric mucin | CAS No.: 84082-64-4 |
| Supply Ability: 10g | Release date: 2024/11/19 |
Product Introduction
Bioactivity
| Name | Gastric mucin |
| Description | Gastric mucin, a large glycoprotein, is thought to play a major role in protecting the gastrointestinal tract from acid, proteases, pathogenic microorganisms, and mechanical trauma. |
| In vitro | Gastric mucin, a large glycoprotein, plays a crucial role in protecting the gastrointestinal tract against acid, proteases, pathogens, and mechanical damage. It is also implicated in gastric injuries caused by Helicobacter pylori, potentially leading to gastritis, peptic ulcers, and gastric cancer. Gastric mucins are classified into two categories based on histochemical properties: surface mucous cell-type mucin, secreted by surface cells, and glandular mucins, secreted by deeper mucosal cells including mucous neck, cardiac gland, and pyloric gland cells. The O-glycans within gastric mucin may act as natural antibiotics, offering protection against H. pylori infection. Additionally, gastric mucin guards the gastrointestinal epithelium by neutralizing oxidants in the lumen, despite reducing its viscoelastic properties. Studies have shown that both unaltered and pronase-treated mucin can effectively neutralize hydroxyl radicals, with no significant difference in their scavenging abilities. A concentration of 10 mg/mL of mucin is required to halve malondialdehyde production, applicable to both mucin types. |
| Storage | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
| Solubility Information | DMSO : < 1 mg/mL (insoluble or slightly soluble) H2O : < 0.1 mg/mL (insoluble) 1M NaOH : < 1 mg/mL (insoluble) |
| Keywords | Antibiotic | inhibit | Inhibitor | Bacterial | Gastric mucin |
| Inhibitors Related | Neomycin sulfate | Dimethyl sulfoxide |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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