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ChemicalBook >> CAS DataBase List >>TP-004

TP-004

CAS No.
1454299-21-8
Chemical Name:
TP-004
Synonyms
TP-004;TP004,TP 004;(3R)-1-[4-Methyl-5-[6-(trifluoromethyl)-1H-indazol-4-yl]pyrimidin-2-yl]pyrrolidin-3-ol;3-Pyrrolidinol, 1-[4-methyl-5-[6-(trifluoromethyl)-1H-indazol-4-yl]-2-pyrimidinyl]-, (3R)-
CBNumber:
CB95867355
Molecular Formula:
C17H16F3N5O
Molecular Weight:
363.34
MDL Number:
MFCD32701911
MOL File:
1454299-21-8.mol
Last updated:2025-04-17 18:22:24

TP-004 Properties

Boiling point 583.2±60.0 °C(Predicted)
Density 1.464±0.06 g/cm3(Predicted)
pka 10.72±0.40(Predicted)
form Solid
color Light yellow to khaki

TP-004 Chemical Properties,Uses,Production

Uses

TP-004 is a potent and reversible inhibitor of methionine aminopeptidase 2 (MetAP2), with an IC50 of 6 nM[1].

References

[1] Cheruvallath, Z., et al. Discovery of potent, reversible MetAP2 inhibitors via fragment based drug discovery and structure based drug design—Part 1. Bioorganic & Medicinal Chemistry Letters, 26(12), 2774–2778.

TP-004 Preparation Products And Raw materials

Raw materials

Preparation Products

TP-004 Suppliers

Global( 10)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32275 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6312 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38664 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6777 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11218 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11973 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 20029 58
Cayman Chemical Company 800-364-9897 sales@caymanchem.com China 27736 58
Biosynth Biological Technology (Suzhou) Co Ltd 51288865780 sales@biosynth.com China 233051 58

View Lastest Price from TP-004 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
TP-004 pictures 2024-10-28 TP-004
1454299-21-8
 US $393.00-1570.00 / mg 10g TargetMol Chemicals Inc.
  • TP-004 pictures
  • TP-004
    1454299-21-8
  • US $393.00-1570.00 / mg
  • TargetMol Chemicals Inc.
TP-004 3-Pyrrolidinol, 1-[4-methyl-5-[6-(trifluoromethyl)-1H-indazol-4-yl]-2-pyrimidinyl]-, (3R)- TP004,TP 004 (3R)-1-[4-Methyl-5-[6-(trifluoromethyl)-1H-indazol-4-yl]pyrimidin-2-yl]pyrrolidin-3-ol 1454299-21-8