Yohimbine-[13C,D3]
![Yohimbine-[13C,D3] Structure](CAS/20180703/GIF/1261254-59-4.gif)
- CAS No.
- 1261254-59-4
- Chemical Name:
- Yohimbine-[13C,D3]
- Synonyms
- Yohimbine-[13C,D3];METHYL-D3 ESTER, 98%);YOHIMBINE (METHYL-13C, 99%;Yohimbine-(methyl-13C,d? ester);Yohimbine-(methyl-13C,d3 ester) >=99 atom %, >=98 atom % (CP);Yohimbine-(methyl-13C,d3 ester)
- CBNumber:
- CB92741449
- Molecular Formula:
- C21H23D3N2O3
- Molecular Weight:
- 358.470225334
- MDL Number:
- MFCD20524891
- MOL File:
- 1261254-59-4.mol
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301+H311+H331 |
| Precautionary statements | P280-P301+P310+P330-P302+P352+P312-P304+P340+P311 |
| RIDADR | UN 1544PSN2 6.1 / PGII |
| WGK Germany | 3 |
Yohimbine-[13C,D3] price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 731242 | Yohimbine-(methyl-13C,d3 ester) ≥99 atom %, ≥98 atom % (CP) | 1261254-59-4 | 5mg | $445 | 2024-03-01 | Buy |
| Sigma-Aldrich | 731242 | Yohimbine-(methyl-13C,d3 ester) ≥99 atom %, ≥98 atom % (CP) | 1261254-59-4 | 10mg | $812 | 2024-03-01 | Buy |
| IsoSciences | 10075 | Yohimbine-[13C,d3] ≥98% | 1261254-59-4 | 5mg | $300 | 2021-12-16 | Buy |
| IsoSciences | 10075 | Yohimbine-[13C,d3] ≥98% | 1261254-59-4 | 10mg | $551 | 2021-12-16 | Buy |
Yohimbine-[13C,D3] Chemical Properties,Uses,Production
Uses
Yohimbine-13C,d3 is the 13C- and deuterium labeled Yohimbine. Yohimbine is a potent and relatively nonselective alpha 2-adrenergic receptor (AR) antagonist, with IC50 of 0.6 μM.
References
[1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. DOI:10.1177/1060028018797110
[2] Saeed SA, et al. Signaling mechanisms mediated by G-protein coupled receptors in human platelets. Acta Pharmacol Sin. 2004 Jul;25(7):887-892. PMID:15210061
[3] Blanchard RJ, et al. Yohimbine potentiates active defensive responses to threatening stimuli in Swiss-Webster mice. Pharmacol Biochem Behav. 1993 Mar;44(3):673-681. DOI:10.1016/0091-3057(93)90185-v
[4] Fuller BB, et al. Downregulation of tyrosinase activity in human melanocyte cell cultures by yohimbine. J Invest Dermatol. 2000 Feb;114(2):268-276. DOI:10.1046/j.1523-1747.2000.00860.x
Yohimbine-[13C,D3] Preparation Products And Raw materials
Raw materials
Preparation Products
Yohimbine-[13C,D3] Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51456 | 80 |
| Alta Scientific Co., Ltd. | 022-6537-8550 15522853686 | sales@altasci.com.cn | China | 4511 | 55 |
| Energy Chemical | 021-58432009 400-005-6266 | marketing1@energy-chemical.com | China | 44814 | 58 |
| Qingdao Tenglong microwave technology co., LTD. | 0532-83818797 18561885118 | market@tlwb.com.cn | China | 3944 | 58 |
| Reer Technology (Shanghai) Co., LTD | 021-64400900 15800436310 | bessey@reertech.com | China | 4105 | 58 |
| Shanghai isotope chemical co.,ltd | 021-51600108 13062666369 | sales@isotopechem.com | China | 4273 | 58 |
| Shanghai Saikerui Biotechnology Co. , Ltd. | 021-58000709 15900491054 | info@scrbio.com | China | 9522 | 58 |
| Shanghai Beiwanta Biotechnology Co., Ltd. | 021-67187366 19901745723 | info@bwtlab.com | China | 9384 | 58 |
| Nanjing Shizhou Biology Technology Co.,Ltd | 17301488900 | judy.xia@synzest.com | China | 12582 | 58 |