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ChemicalBook >> CAS DataBase List >>3,4-O-Isopropylidene shikimic acid

3,4-O-Isopropylidene shikimic acid

CAS No.
183075-03-8
Chemical Name:
3,4-O-Isopropylidene shikimic acid
Synonyms
4-O-Isopropylidene shikimic acid;3,4-O-Isopropylidene shikimic acid;3,4-O-Isopropylidene shikimic acid USP/EP/BP;3,4-O-Isopropylidene-shikimic acid, 10 mM in DMSO;7-Hydroxy-2,2-diMethyl-3a,6,7,7a-tetrahydrobenzo[d][1,3]dioxole-5-carboxylic acid;(3aR,7R,7aS)-7-Hydroxy-2,2-dimethyl-3a,6,7,7a-tetrahydrobenzo[d][1,3]dioxole-5-carboxylic acid;1,3-Benzodioxole-5-carboxylic acid, 3a,6,7,7a-tetrahydro-7-hydroxy-2,2-dimethyl-, (3aR,7R,7aS)-;anti-inflammatory,acid,3,4 O Isopropylidene shikimic acid,antioxidant,3,4OIsopropylideneshikimic acid,Inhibitor,inhibit,shikimic
CBNumber:
CB92519352
Molecular Formula:
C10H14O5
Molecular Weight:
214.22
MDL Number:
MFCD17214943
MOL File:
183075-03-8.mol
MSDS File:
SDS
Last updated:2025-04-28 21:36:36

3,4-O-Isopropylidene shikimic acid Properties

solubility Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
form Powder
color Off-white to light yellow

3,4-O-Isopropylidene shikimic acid price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Arctom CFN99852 3,4-O-Isopropylideneshikimicacid 183075-03-8 5mg $293 2021-12-16 Buy
Crysdot CD32002174 3,4-O-IsopropylideneShikimicAcid 95+% 183075-03-8 5mg $470 2021-12-16 Buy
Product number Packaging Price Buy
CFN99852 5mg $293 Buy
CD32002174 5mg $470 Buy

3,4-O-Isopropylidene shikimic acid Chemical Properties,Uses,Production

Description

3,4-Oxo- isopropylidene-shikimic acid has significant anti-inflammatory effect which may be related to inhibiting the production of prostaglandin E2 and protecting free radical against oxidation. 3,4-Oxo-isopropylidene-shikimic acid has protective effects on experimental colitis induced by trinitrobenzenesulfonic acid in rats, probably due to an antioxidant action. 3. 3,4-Oxo-isopropylidene-shikimic acid has anti-thrombosis effect, it inhibits thrombosis by anti-platelet-aggregation. 4. 3,4-Oxo-isopropylidene shikimic acid relieves the brain edema of rats subjected to MCAT by improving the energy metabolism and Na +, K +-ATPase activity in rat brain tissue. 5. 3,4-Oxo-isopropylidene-shikimic acid can inhibit adhesion of polymorphonuclear leukocyte to TNF-alpha-induced endothelial cells in vitro. 6. 3,4-Oxo-isopropylidene-shikimic acid has analgesic and antioxidant activities, it exhibits moderate antioxidant activity by scavenging the superoxide radical and hydroxyl radical with IC50 values of 0.214 and 0.450 ug/mL, respectively. 7. 3,4-Oxo-isopropylidene-shikimic acid has exhibited ameliorative effect on cognitive impairment in experimental animal models of dementia, it can promote adipogenesis by up-regulating expressions of C/EBP β, PPAR γ, C/EBP α, aP2 and FAS, and also stimulate adipokines during adipocyte differentiation, suggests that stimulation of adipokines and cognitive enhancing effect of 3,4-oxo-isopropylidene-shikimic acid have some relationship.

Uses

3,4-O-Isopropylidene-shikimicn acid is a natural product that can be isolated from the whole plants of Hypericum wightianum. 3,4-O-Isopropylidene-shikimic acid has anti-inflammatory effect and antioxidant activities[1][2].

target

NO | NOS | PGE | TNF-α | PPAR | Sodium Channel | ATPase | Potassium Channel

References

[1] Shu-Hong Tao, et al. Note: A New Flavone from Hypericum Wightianum. Journal of Asian Natural Products Research. 2004. 6(4), 307-310.
[2] Jianfeng Xing, et al. Anti-inflammatory effect of 3,4-oxo-isopropylidene-shikimic acid on acetic acid-induced colitis in rats. Inflammation. 2012 Dec;35(6):1872-9. DOI:10.1007/s10753-012-9509-7

3,4-O-Isopropylidene shikimic acid Preparation Products And Raw materials

Raw materials

Preparation Products

3,4-O-Isopropylidene shikimic acid Suppliers

Global( 73)Suppliers
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Chengdu Biopurify Phytochemicals Ltd. 		+86-28-82633860; +8618080483897 sales@biopurify.com China 3751 58
TargetMol Chemicals Inc. 		+17819995354 marketing@targetmol.com United States 32285 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250 1026@dideu.com China 22866 58
TargetMol Chemicals Inc. 		support@targetmol.com United States 38668 58
Mensura Group Limited 		+8618109034517 1058503172@qq.com China 2900 58
DAYANG CHEM (HANGZHOU) CO.,LTD 		+86-88938639 +86-17705817739 info@dycnchem.com China 53900 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131957 58
Chembest Research Laboratories Limited +86-21-20908456 sales@BioChemBest.com China 6005 61
BioBioPha Co., Ltd. 0871-65217109 13211707573; y.liu@mail.biobiopha.com China 5653 65
Chengdu Biopurify Phytochemicals Ltd. +86-028-82633397 18982077548 cwb1@biopurify.cn China 2376 60

View Lastest Price from 3,4-O-Isopropylidene shikimic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
3,4-O-Isopropylidene-shikimic acid pictures 2025-04-27 3,4-O-Isopropylidene-shikimic acid
183075-03-8
 US $68.00-248.00 / mg 99.47% 10g TargetMol Chemicals Inc.
3,4-O-Isopropylidene shikimic acid 7-Hydroxy-2,2-diMethyl-3a,6,7,7a-tetrahydrobenzo[d][1,3]dioxole-5-carboxylic acid 1,3-Benzodioxole-5-carboxylic acid, 3a,6,7,7a-tetrahydro-7-hydroxy-2,2-dimethyl-, (3aR,7R,7aS)- 4-O-Isopropylidene shikimic acid 3,4-O-Isopropylidene shikimic acid USP/EP/BP anti-inflammatory,acid,3,4 O Isopropylidene shikimic acid,antioxidant,3,4OIsopropylideneshikimic acid,Inhibitor,inhibit,shikimic (3aR,7R,7aS)-7-Hydroxy-2,2-dimethyl-3a,6,7,7a-tetrahydrobenzo[d][1,3]dioxole-5-carboxylic acid 3,4-O-Isopropylidene-shikimic acid, 10 mM in DMSO 183075-03-8