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ChemicalBook >> CAS DataBase List >>N-(3-Chlorophenyl)-N-[[5-[5-(difluoromethyl)-1,3,4-oxadiazol-2-yl]-2-pyridinyl]methyl]methanesulfonamide

N-(3-Chlorophenyl)-N-[[5-[5-(difluoromethyl)-1,3,4-oxadiazol-2-yl]-2-pyridinyl]methyl]methanesulfonamide

CAS No.
2071224-39-8
Chemical Name:
N-(3-Chlorophenyl)-N-[[5-[5-(difluoromethyl)-1,3,4-oxadiazol-2-yl]-2-pyridinyl]methyl]methanesulfonamide
Synonyms
HDAC-IN-58;N-(3-Chlorophenyl)-N-[[5-[5-(difluoromethyl)-1,3,4-oxadiazol-2-yl]-2-pyridinyl]methyl]methanesulfonamide
CBNumber:
CB913686463
Molecular Formula:
C16H13ClF2N4O3S
Molecular Weight:
414.82
MDL Number:
MOL File:
2071224-39-8.mol
Last updated:2025-04-18 09:53:02

N-(3-Chlorophenyl)-N-[[5-[5-(difluoromethyl)-1,3,4-oxadiazol-2-yl]-2-pyridinyl]methyl]methanesulfonamide Properties

Boiling point 570.6±60.0 °C(Predicted)
Density 1.498±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted)
pka 0.29±0.24(Predicted)

N-(3-Chlorophenyl)-N-[[5-[5-(difluoromethyl)-1,3,4-oxadiazol-2-yl]-2-pyridinyl]methyl]methanesulfonamide Chemical Properties,Uses,Production

Uses

HDAC-IN-58 is a HDAC inhibitor. HDAC-IN-58 has HDAC6-specific inhibition activity with an IC50 value of 2.06 nM. HDAC-IN-58 can be used for the research of chronic diseases, including neurodegenerative and psychiatric conditions[1].

References

[1] Motlová L, et al. Comprehensive Mechanistic View of the Hydrolysis of Oxadiazole-Based Inhibitors by Histone Deacetylase 6 (HDAC6). ACS Chem Biol. 2023 Jul 21;18(7):1594-1610. DOI:10.1021/acschembio.3c00212

N-(3-Chlorophenyl)-N-[[5-[5-(difluoromethyl)-1,3,4-oxadiazol-2-yl]-2-pyridinyl]methyl]methanesulfonamide Preparation Products And Raw materials

Raw materials

Preparation Products

N-(3-Chlorophenyl)-N-[[5-[5-(difluoromethyl)-1,3,4-oxadiazol-2-yl]-2-pyridinyl]methyl]methanesulfonamide Suppliers

Global( 6)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
TargetMol Chemicals Inc. 		+8613564774135 zijue.cai@tsbiochem.com United States 19897 58
Shanghai Beckham Medical Technology Co., Ltd 021-13816613772 13816613772 huahero21@sina.com China 993 55
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 6345 55
Shanghai Chaolan Chemical Technology Center 021-QQ：65489617 15618227136 Sales@ATKchemical.com China 9342 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19820 58

View Lastest Price from N-(3-Chlorophenyl)-N-[[5-[5-(difluoromethyl)-1,3,4-oxadiazol-2-yl]-2-pyridinyl]methyl]methanesulfonamide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
HDAC-IN-58 pictures 2024-11-19 HDAC-IN-58
2071224-39-8
 US $2500.00-1520.00 / mg 10g TargetMol Chemicals Inc.
  • HDAC-IN-58 pictures
  • HDAC-IN-58
    2071224-39-8
  • US $2500.00-1520.00 / mg
  • TargetMol Chemicals Inc.
N-(3-Chlorophenyl)-N-[[5-[5-(difluoromethyl)-1,3,4-oxadiazol-2-yl]-2-pyridinyl]methyl]methanesulfonamide HDAC-IN-58 2071224-39-8