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1H-1,4-Diazepine, hexahydro-1-[[4-(1-methylethyl)phenyl]methyl]-4-[2-[2-(4-pyridinyl)-6-(2-thienyl)-4-pyrimidinyl]ethyl]-

CAS No.
2249757-45-5
Chemical Name:
1H-1,4-Diazepine, hexahydro-1-[[4-(1-methylethyl)phenyl]methyl]-4-[2-[2-(4-pyridinyl)-6-(2-thienyl)-4-pyrimidinyl]ethyl]-
Synonyms
FtsZ-IN-2;1H-1,4-Diazepine, hexahydro-1-[[4-(1-methylethyl)phenyl]methyl]-4-[2-[2-(4-pyridinyl)-6-(2-thienyl)-4-pyrimidinyl]ethyl]-
CBNumber:
CB912621975
Molecular Formula:
C30H35N5S
Molecular Weight:
497.7
MDL Number:
MOL File:
2249757-45-5.mol
Last updated:2025-04-18 09:52:59

1H-1,4-Diazepine, hexahydro-1-[[4-(1-methylethyl)phenyl]methyl]-4-[2-[2-(4-pyridinyl)-6-(2-thienyl)-4-pyrimidinyl]ethyl]- Properties

Boiling point 586.0±50.0 °C(Predicted)
Density 1.150±0.06 g/cm3(Predicted)
pka 8.43±0.10(Predicted)

1H-1,4-Diazepine, hexahydro-1-[[4-(1-methylethyl)phenyl]methyl]-4-[2-[2-(4-pyridinyl)-6-(2-thienyl)-4-pyrimidinyl]ethyl]- Chemical Properties,Uses,Production

Uses

FtsZ-IN-2 (Compound 19) is an inhibitor of the bacterial cell division protein FtsZ with GTPase inhibitory activity. FtsZ-IN-2 exhibits anti-staphylococcal activity with MIC values of 2 μg/ml for MSSA and MRSA[1].

References

[1] Buroni S, et al. The cell division protein FtsZ as a cellular target to hit cystic fibrosis pathogens. Eur J Med Chem. 2020 Mar 15;190:112132. DOI:10.1016/j.ejmech.2020.112132

1H-1,4-Diazepine, hexahydro-1-[[4-(1-methylethyl)phenyl]methyl]-4-[2-[2-(4-pyridinyl)-6-(2-thienyl)-4-pyrimidinyl]ethyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

1H-1,4-Diazepine, hexahydro-1-[[4-(1-methylethyl)phenyl]methyl]-4-[2-[2-(4-pyridinyl)-6-(2-thienyl)-4-pyrimidinyl]ethyl]- Suppliers

Global( 2)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+8613564774135 zijue.cai@tsbiochem.com United States 19905 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 20029 58

View Lastest Price from 1H-1,4-Diazepine, hexahydro-1-[[4-(1-methylethyl)phenyl]methyl]-4-[2-[2-(4-pyridinyl)-6-(2-thienyl)-4-pyrimidinyl]ethyl]- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
FtsZ-IN-2 pictures 2025-05-02 FtsZ-IN-2
2249757-45-5
 US $1980.00-2500.00 / mg 10g TargetMol Chemicals Inc.
  • FtsZ-IN-2 pictures
  • FtsZ-IN-2
    2249757-45-5
  • US $1980.00-2500.00 / mg
  • TargetMol Chemicals Inc.
1H-1,4-Diazepine, hexahydro-1-[[4-(1-methylethyl)phenyl]methyl]-4-[2-[2-(4-pyridinyl)-6-(2-thienyl)-4-pyrimidinyl]ethyl]- FtsZ-IN-2 2249757-45-5